Lightnews — Scholar-powered news

David Gaboriau @dgaboriau.bsky.social · 4h

Wait what

Cameron Thrash @jcamthrash.bsky.social · 21h

Direct single-molecule detection and super-resolution imaging with a low-cost portable smartphone-based microscope www.nature.com/articles/s41... #jcampubs

Direct single-molecule detection and super-resolution imaging with a low-cost portable smartphone-based microscope - Nature Communications

Loretan and colleagues present a low-cost smartphone-based microscope capable of detecting single-molecule fluorescence. This approach opens doors to personalised and widely distributed applications in diagnostics, biosensing, and science education.

www.nature.com

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David Gaboriau @dgaboriau.bsky.social · 4h

Glad you and your family are ok! Good idea to take the photos!

Reposted by David Gaboriau

Cahir O'Kane @cahirokane.bsky.social · 1d

Sad to hear of the death of John Gurdon this morning, aged 92.

Professor Sir John Gurdon FRS (1933-2025) | Magdalene College

Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.

www.magd.cam.ac.uk

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David Gaboriau @dgaboriau.bsky.social · 1d

Top position in Paris with Jean-Yves @jytinevez.bsky.social

#bioimageanalysis 🔬

Jean-Yves Tinevez @jytinevez.bsky.social · 1d

Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...

Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA

Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...

forum.image.sc

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David Gaboriau @dgaboriau.bsky.social · 2d

Ahead of the Physics Nobel tomorrow, a thread on a Nobel not as famous as others.

Nonetheless, Lippmann had that ace quote:

“Life is short and progress is slow.” 👌

Margaret Harris @drmlharris.bsky.social · 2d

And the funny thing is, Lippmann knew this. He even ended his Nobel Prize lecture by acknowledging that, at over one minute, the exposure times for his method were “too long for the portrait”. Though further improvements were possible, he concluded, “Life is short and progress is slow.” (7/n) 🧪⚛️

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David Gaboriau @dgaboriau.bsky.social · 4d

Antibodies are fickle things!
I hope it works out for your IF!

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David Gaboriau @dgaboriau.bsky.social · 5d

Neat playlists!

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Reposted by David Gaboriau

Christophe 🔬 L @christlet.bsky.social · 5d

Want to hear a mid-career PI pontificate about science, career and cooking? Today's your lucky day thanks to The Microscopists podcast! Thanks Peter @yorkbioimaging.bsky.social for having me 🎙️🎧
themicroscopists.bitesizebio.com/episodes/chr...

The Microscopists | Christophe Leterrier (CNRS & Aix-Marseille Université)

This time on The Microscopists, we're joined by Christophe Leterrier, team leader at NeuroCyto in Marseille and director of a Nikon Center of Excellence for super-resolution microscopy.Christophe r...

themicroscopists.bitesizebio.com

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David Gaboriau @dgaboriau.bsky.social · 5d

Make one a year and give it as part of the best poster prize ☕️

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Reposted by David Gaboriau

Dave Barry @david-j-barry.bsky.social · 6d

I forgot that I had this made. As a prototype that never went into full production, it's the only one in existence and, therefore, highly desirable.

Let's start the bidding at £1,809, £1 for every day since the very first CBIAS.

For an extra 50%, you can have it signed by @martinjones.bsky.social.

Crick BioImage Analysis Symposium 2024 Commemorative Mug

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David Gaboriau @dgaboriau.bsky.social · 6d

Full cell antibody purification!

Clever trick, could also work for IF or FACS

Victor Tatarskiy @greenrat.bsky.social · 6d

Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass...
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky

On the left - western blot of B16F10 cells wt and KO for CDK8. Our in house produced antibodies give a lot of unspecific bands. On the right same probes with antibodies preincubated with fixed CDK8 KO cells - there is a specific band and faint unspecific bands, which can be probably eliminated with increase of amount of KO cells.

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Reposted by David Gaboriau

Dr Rachel Clarke @drrachelclarke.com · 7d

Here I am in 2020 in the flimsiest, most pitful PPE - like so many other NHS staff, some of whom died from the Covid they caught in their hospitals.

Tory peer Michelle Mone - who today lost her legal case & must repay the govt £122m - dares to claim she’s been ‘scapegoated’.

What, Michelle? 🧵

Rachel wearing very flimsy looking apron, mask and visor in NHS setting

140 1.2K 3K

Reposted by David Gaboriau

Cahir O'Kane @cahirokane.bsky.social · 7d

When BCE (before the confocal era) turned into CE (confocal era) - 1987

Nature Reviews Molecular Cell Biology @natrevmcb.nature.com · 8d

New Online! The advent of confocal laser scanning microscopy in biological research

The advent of confocal laser scanning microscopy in biological research

Nature Reviews Molecular Cell Biology, Published online: 01 October 2025; doi:10.1038/s41580-025-00905-5The advent of laser-scanning confocal microscopy revolutionized cell biology, offering unprecedented resolution and depth and enabling scientists to visualize cellular structures in 3D.

bit.ly

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Reposted by David Gaboriau

Mayor of London, Sadiq Khan @london.gov.uk · 8d

184 years earlier than predicted, London has met the legal limits for toxic NO2 for the first time.

This historic milestone proves that bold action like expanding ULEZ works, protecting children’s health and giving millions cleaner air to breathe.

London Ulez reduced nitrogen dioxide to legal limit, mayor says

The mayor of London says the fall in airborne toxins is due to the Ultra low emission zone expansion.

www.bbc.co.uk

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Reposted by David Gaboriau

Siân Culley @superresolusian.bsky.social · 10d

BioImage analysis friends - King's are recruiting for a full-time, permanent facility position! Come and work with fun microscopes and fun people (and me!) - please share! www.kcl.ac.uk/jobs/126345-...

Bioimage Analysis Specialist | King's College London

www.kcl.ac.uk

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Reposted by David Gaboriau

Imperial Medicine @imperialmed.bsky.social · 10d

For the first time, @imperialcollegeldn.bsky.social, @ucl.ac.uk & @uniofnottingham.bsky.social scientists have captured in detail how life-saving #antibiotics break through bacterial armour.

The findings could help tackle deadly drug-resistant infections.

www.imperial.ac.uk/news/269074/...

Amazing images show how antibiotics pierce bacterial armour | Imperial News | Imperial College London

UK researchers have shown for the first time in stunning detail how life-saving antibiotics act against harmful bacteria.

www.imperial.ac.uk

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David Gaboriau @dgaboriau.bsky.social · 10d

Not science, but important:
If there is a fishy smell next to a power socket, it might be the smell of electric cables melting!
We did not know, so I’m sharing this.
If you do smell this (reminded me of salmon skin after roasting), call an electrician straight away.
⚡️⚡️⚡️

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David Gaboriau @dgaboriau.bsky.social · 12d

Wow that’s super cool!

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Reposted by David Gaboriau

AIR @airfrenchband.bsky.social · 12d

Happy 25th anniversary to the Virgin Suicides soundtrack – 25 years of spacey, dark, scary music !

The Virgin Suicides Redux is out everywhere today !

→ air.lnk.to/TVSRedux

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Reposted by David Gaboriau

Christophe 🔬 L @christlet.bsky.social · 13d

#FluorescenceFriday: getting ready for #GEF25, playing with Ciarán's stunning ExM data

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Reposted by David Gaboriau

Matthew Cobb @matthewcobb.bsky.social · 13d

And here we are. Another damn’d thick, square book. A real wrist-sprainer. UK edition (pictured) has endpapers showing Crick and Brenner’s blackboard and colour plates. Both U.K. and US editions have sections heralded by a double page photo as here. Loads of illustrations. Out in November!

Cover and spine of CRICK, my biography of Francis Crick

Double page photo of Crick at blackboard with section title The Central Problem

Colour plate showing Crick at Cold Spring Harbor in 1954.

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Reposted by David Gaboriau

Fabrice Senger @senger.bsky.social · 13d

We see past time in a telescope and present time in a microscope. Hence the apparent enormities of the present.

Victor Hugo

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Reposted by David Gaboriau

jmutterer.bsky.social @jmutterer.bsky.social · 13d

Reply with cool microscopy quotes, Jules Girard, 1877, "les plantes étudiées au microscope"

La science est redevable au microscope et à l'art de s'en servir d'un grand nombre de découvertes.

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David Gaboriau @dgaboriau.bsky.social · 13d

Biscuits, someone has left oil on the 10x again…

Myself

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David Gaboriau @dgaboriau.bsky.social · 13d

B y the means of Telescopes, there is nothing so far distant but may be represented to our view; and by the help of Microscopes, there is nothing so small, as to escape our enquiry.

Robert Hooke

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