Dr June M McKoy
@drjunejd.bsky.social
Physician Scientist| Health Policy|Bioethicist|GeroOnc researcher| Pharmacovigilance Research| Assoc. Editor JNCCN| Edit Board J Onc Practice (JOP) |Edit Board J Geriatric Onc (JGO) |ABIM Governance Board|Founder & CEO BlackStethoscopes-2, LLC🇯🇲🇬🇧🇺🇸 My views.
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Dr June M McKoy
@drjunejd.bsky.social
· Nov 16
As a Black woman physician I do not have the luxury that my counterparts have of moving seamlessly from formal to informal roles without negative consequences...thus my first name is ALWAYS “Doctor” @drjunejd.bsky.social
Reposted by Dr June M McKoy
Our recent publication in British Journal of Cancer www.nature.com/articles/s41...
Circulating tumour cells are a prognostic indicator in advanced high-grade serous ovarian cancer and are associated with platelets and immune cells following dissemination - British Journal of Cancer
British Journal of Cancer - Circulating tumour cells are a prognostic indicator in advanced high-grade serous ovarian cancer and are associated with platelets and immune cells following dissemination
www.nature.com
November 9, 2025 at 9:50 PM
Our recent publication in British Journal of Cancer www.nature.com/articles/s41...
Reposted by Dr June M McKoy
Is #cancer associated #thrombosis caused predominantly by the tumour or treatment. #chemotherapy has unique effects on the activated protein C pathway which may be important in VTE occuring during chemotherapy doi.org/10.1016/j.th....
January 9, 2025 at 10:59 AM
Is #cancer associated #thrombosis caused predominantly by the tumour or treatment. #chemotherapy has unique effects on the activated protein C pathway which may be important in VTE occuring during chemotherapy doi.org/10.1016/j.th....
Reposted by Dr June M McKoy
The APOE4 allele, present in >20% of the population, is a significant risk marker for #Alzheimers. What if we could flip it to the protective APOE2 allele?
Encouraging results in the experimental model
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Encouraging results in the experimental model
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 11, 2025 at 3:20 PM
The APOE4 allele, present in >20% of the population, is a significant risk marker for #Alzheimers. What if we could flip it to the protective APOE2 allele?
Encouraging results in the experimental model
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Encouraging results in the experimental model
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Congratulations Prof William Brady @williambrady.bsky.social on
being named a recipient of the 2025 Kabiller Science of Empathy Prize. As Dean Cornelli notes, this award “advances the understanding of empathy and celebrates Kellogg’s rigorous approach to the subject” @drjunejd.bsky.social
being named a recipient of the 2025 Kabiller Science of Empathy Prize. As Dean Cornelli notes, this award “advances the understanding of empathy and celebrates Kellogg’s rigorous approach to the subject” @drjunejd.bsky.social
November 2, 2025 at 4:24 AM
Congratulations Prof William Brady @williambrady.bsky.social on
being named a recipient of the 2025 Kabiller Science of Empathy Prize. As Dean Cornelli notes, this award “advances the understanding of empathy and celebrates Kellogg’s rigorous approach to the subject” @drjunejd.bsky.social
being named a recipient of the 2025 Kabiller Science of Empathy Prize. As Dean Cornelli notes, this award “advances the understanding of empathy and celebrates Kellogg’s rigorous approach to the subject” @drjunejd.bsky.social
Happy Halloween MedX and all those who follow and support our work. It’s nice to decompress this evening with my wonderful clinical team @drjunejd.bsky.social
October 31, 2025 at 10:30 PM
Happy Halloween MedX and all those who follow and support our work. It’s nice to decompress this evening with my wonderful clinical team @drjunejd.bsky.social
Stunning Grand Rounds on “Exceptional Longevity: What’s it really like? Centenarians, their Kids, and How They Get There.”
Delivered @medicalcollegeofwi.bsky.social by renowned GeroScientist Dr Thomas Perls an international leader in the field of human exceptional longevity @drjunejd.bsky.social
Delivered @medicalcollegeofwi.bsky.social by renowned GeroScientist Dr Thomas Perls an international leader in the field of human exceptional longevity @drjunejd.bsky.social
October 26, 2025 at 3:39 PM
Stunning Grand Rounds on “Exceptional Longevity: What’s it really like? Centenarians, their Kids, and How They Get There.”
Delivered @medicalcollegeofwi.bsky.social by renowned GeroScientist Dr Thomas Perls an international leader in the field of human exceptional longevity @drjunejd.bsky.social
Delivered @medicalcollegeofwi.bsky.social by renowned GeroScientist Dr Thomas Perls an international leader in the field of human exceptional longevity @drjunejd.bsky.social
Reposted by Dr June M McKoy
‼️Our latest study, “Loss of STAT3 in acute myeloid leukemia favors tissue infiltration linked to CXCR4 signaling,” is now out in @bloodneoplasia.bsky.social
#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...
#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...
October 15, 2025 at 2:53 PM
‼️Our latest study, “Loss of STAT3 in acute myeloid leukemia favors tissue infiltration linked to CXCR4 signaling,” is now out in @bloodneoplasia.bsky.social
#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...
#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...
I’m having an amazing time at the National Academy of Medicine (NAM) annual mtg in Washington, D.C. today. AI is front and center as physician and nurse scientists discuss AI within the framework of healthcare in all its many facets @nationalacademies.org @drjunejd.bsky.social
October 20, 2025 at 6:30 PM
I’m having an amazing time at the National Academy of Medicine (NAM) annual mtg in Washington, D.C. today. AI is front and center as physician and nurse scientists discuss AI within the framework of healthcare in all its many facets @nationalacademies.org @drjunejd.bsky.social
This Radiation Mask…
My patient graduated from cancer this week.
This mask was his constant companion. Representing struggle and resilience.
Protection and escape.
This ritual transformation.
When words are insufficient …symbols supersede @drjunejd.bsky.social
My patient graduated from cancer this week.
This mask was his constant companion. Representing struggle and resilience.
Protection and escape.
This ritual transformation.
When words are insufficient …symbols supersede @drjunejd.bsky.social
October 17, 2025 at 3:19 AM
This Radiation Mask…
My patient graduated from cancer this week.
This mask was his constant companion. Representing struggle and resilience.
Protection and escape.
This ritual transformation.
When words are insufficient …symbols supersede @drjunejd.bsky.social
My patient graduated from cancer this week.
This mask was his constant companion. Representing struggle and resilience.
Protection and escape.
This ritual transformation.
When words are insufficient …symbols supersede @drjunejd.bsky.social
Reposted by Dr June M McKoy
💉 2024–25 Covid-19 vaccine effectiveness
In U.S. veterans, the updated vaccine reduced 6-month risks of Covid-related ED visits (-29%), hospitalisations (-39%), and deaths (-64%) vs flu-only group.
🔗 doi.org/10.1056/NEJMoa2510226
#SciComm #COVID19 #Vaccines 🧪
In U.S. veterans, the updated vaccine reduced 6-month risks of Covid-related ED visits (-29%), hospitalisations (-39%), and deaths (-64%) vs flu-only group.
🔗 doi.org/10.1056/NEJMoa2510226
#SciComm #COVID19 #Vaccines 🧪
Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans | NEJM
Amid the declining clinical severity of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) infection and diminishing public uptake of annual coronavirus disease
2019 (Covid-19) vaccines, ...
doi.org
October 11, 2025 at 4:10 AM
💉 2024–25 Covid-19 vaccine effectiveness
In U.S. veterans, the updated vaccine reduced 6-month risks of Covid-related ED visits (-29%), hospitalisations (-39%), and deaths (-64%) vs flu-only group.
🔗 doi.org/10.1056/NEJMoa2510226
#SciComm #COVID19 #Vaccines 🧪
In U.S. veterans, the updated vaccine reduced 6-month risks of Covid-related ED visits (-29%), hospitalisations (-39%), and deaths (-64%) vs flu-only group.
🔗 doi.org/10.1056/NEJMoa2510226
#SciComm #COVID19 #Vaccines 🧪
READ OUR COMMENTARY ON PARP DIFFUSION THROUGHOUT THE USA @drjunejd.bsky.social
October 3, 2025 at 3:18 AM
READ OUR COMMENTARY ON PARP DIFFUSION THROUGHOUT THE USA @drjunejd.bsky.social
Exciting! The ABIM @abimcert.bsky.social w/the Accreditation Council for Continuing Medical Education has expanded the # of activities for which physicians can earn MOC credits.
🎙️ Hear more from leaders at ACCME and ABIM in their recent podcast conversation: lnkd.in/gQQDZQhy @drjunejd.bsky.social
🎙️ Hear more from leaders at ACCME and ABIM in their recent podcast conversation: lnkd.in/gQQDZQhy @drjunejd.bsky.social
September 30, 2025 at 12:59 PM
Exciting! The ABIM @abimcert.bsky.social w/the Accreditation Council for Continuing Medical Education has expanded the # of activities for which physicians can earn MOC credits.
🎙️ Hear more from leaders at ACCME and ABIM in their recent podcast conversation: lnkd.in/gQQDZQhy @drjunejd.bsky.social
🎙️ Hear more from leaders at ACCME and ABIM in their recent podcast conversation: lnkd.in/gQQDZQhy @drjunejd.bsky.social
Congratulations to my dear friend and colleague Dr David Bentrem! @luriecancer.bsky.social A fantastic pancreatic surgeon, he has incomparable skills in the operating room and practices the art of medicine at the bedside…always prioritizing his patients needs @drjunejd.bsky.social
September 28, 2025 at 3:53 PM
Congratulations to my dear friend and colleague Dr David Bentrem! @luriecancer.bsky.social A fantastic pancreatic surgeon, he has incomparable skills in the operating room and practices the art of medicine at the bedside…always prioritizing his patients needs @drjunejd.bsky.social
Reposted by Dr June M McKoy
Cancer cells hijack neurons to promote their growth. Here (and how) neurons form pseudo-synapses to promote pancreatic cancer's growth cell.com/cancer-cell/...
September 25, 2025 at 8:04 PM
Cancer cells hijack neurons to promote their growth. Here (and how) neurons form pseudo-synapses to promote pancreatic cancer's growth cell.com/cancer-cell/...
Reposted by Dr June M McKoy
Checkpoint inhibitors are the mainstay of cancer immunotherapy. Here's a new review article for the current state of the science and where we're headed www.science.org/doi/10.1126/...
September 26, 2025 at 7:10 PM
Checkpoint inhibitors are the mainstay of cancer immunotherapy. Here's a new review article for the current state of the science and where we're headed www.science.org/doi/10.1126/...
Reposted by Dr June M McKoy
Discovery of the number of ways cancer cell hijack other cells to promote their growth and spread keeps proliferating www.cell.com/cell/fulltex...
Tumors hijack macrophages for iron supply to promote bone metastasis and anemia
Tumor cells mimic erythroblasts by hijacking a specialized macrophage population for
iron supply, thereby promoting metastasis through enhanced adaptation to hypoxia and
contributing to anemia by impa...
www.cell.com
September 3, 2025 at 4:22 PM
Discovery of the number of ways cancer cell hijack other cells to promote their growth and spread keeps proliferating www.cell.com/cell/fulltex...
Reposted by Dr June M McKoy
How can we reawaken the body’s own anti-viral defenses to fight brain cancer?
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏
#BrainTIME 🧠🦠🧪
🧵
www.sciencedirect.com/science/arti...
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏
#BrainTIME 🧠🦠🧪
🧵
www.sciencedirect.com/science/arti...
September 3, 2025 at 12:56 PM
How can we reawaken the body’s own anti-viral defenses to fight brain cancer?
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏
#BrainTIME 🧠🦠🧪
🧵
www.sciencedirect.com/science/arti...
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏
#BrainTIME 🧠🦠🧪
🧵
www.sciencedirect.com/science/arti...
Reposted by Dr June M McKoy
One more diabolical trick of cancer cells: transferring their mitochondria to fibroblasts to promote their growth
nature.com/articles/s43...
nature.com/articles/s43...
Cancer-derived mitochondria fuel fibroblasts to become pro-tumorigenic - Nature Cancer
Cancer-associated fibroblasts represent a functionally diverse and heterogeneous entity within the solid tumor microenvironment. Mitochondrial transfer from cancer cells to fibroblasts is now shown to...
nature.com
August 28, 2025 at 4:10 PM
One more diabolical trick of cancer cells: transferring their mitochondria to fibroblasts to promote their growth
nature.com/articles/s43...
nature.com/articles/s43...
Reposted by Dr June M McKoy
Exposure to heat waves and accelerated biological aging
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Long-term impacts of heatwaves on accelerated ageing - Nature Climate Change
Ageing is linked to environmental factors. This study shows that although participants gradually adapted to heat over time, cumulative exposure to heatwaves had stable and adverse impacts on ageing, e...
www.nature.com
August 25, 2025 at 3:39 PM
Exposure to heat waves and accelerated biological aging
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Dr June M McKoy
How plasma p-Tau markers can predict if and when there will be transition to mild cognitive impairment and Alzheimer’s disease in cognitively unimpaired individuals, along staging of the disease
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Plasma tau biomarkers for biological staging of Alzheimer’s disease - Nature Aging
Montoliu-Gaya, Salvadó et al. develop a blood-based model using tau biomarkers measured in a single analysis enabling biological staging of Alzheimer’s disease to support the diagnosis, prognosis and ...
www.nature.com
August 22, 2025 at 6:21 PM
How plasma p-Tau markers can predict if and when there will be transition to mild cognitive impairment and Alzheimer’s disease in cognitively unimpaired individuals, along staging of the disease
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Gero-onc matters. “Effectiveness of comprehensive geriatric assessment with extensive patient coaching for improving quality of life in older patients with solid tumours receiving systemic therapy (G-oncoCOACH): a multicentre randomised controlled trial” - The Lancet @drjunejd.bsky.social
August 21, 2025 at 1:29 AM
Gero-onc matters. “Effectiveness of comprehensive geriatric assessment with extensive patient coaching for improving quality of life in older patients with solid tumours receiving systemic therapy (G-oncoCOACH): a multicentre randomised controlled trial” - The Lancet @drjunejd.bsky.social
A great review of what I’ll refer to as “glymphatic physiology.” As Cajal has said, “The brain is a world consisting of a number of unexplored continents and great stretches of unknown territory.” @drjunejd.bsky.social
How your brain's metabolic waste products get cleared during sleep, featuring the pivotal 2012 discovery of glymphatics www.scientificamerican.com/article/how-...
August 20, 2025 at 12:26 AM
A great review of what I’ll refer to as “glymphatic physiology.” As Cajal has said, “The brain is a world consisting of a number of unexplored continents and great stretches of unknown territory.” @drjunejd.bsky.social
Congratulations! Wishing you every success on this new journey, Dr Pennell @drjunejd.bsky.social
After 17 years at Cleveland Clinic I am starting today as Senior Vice President and Worldwide Head of Hematology and Oncology Medical Affairs at Bristol-Myers Squibb. I am so thankful to all my colleagues, friends, and patients at the Clinic and will be forever grateful for my experiences there.
August 18, 2025 at 10:08 PM
Congratulations! Wishing you every success on this new journey, Dr Pennell @drjunejd.bsky.social
My mentee, Fares Siddig, is now a meritorious medical student at Columbia University Vagelos College of Physicians and Surgeons @columbiamed.bsky.social He is an outstanding young man w/ a bright future ahead. I can hardly wait to see the impact he will have on our profession @drjunejd.bsky.social
August 9, 2025 at 11:08 PM
My mentee, Fares Siddig, is now a meritorious medical student at Columbia University Vagelos College of Physicians and Surgeons @columbiamed.bsky.social He is an outstanding young man w/ a bright future ahead. I can hardly wait to see the impact he will have on our profession @drjunejd.bsky.social
Reposted by Dr June M McKoy
One in 4 people carry one copy of the APOE4 allele, the strongest known genetic risk factor for Alzheimer's disease. We've just learned how that risk is mediated—the immune system
erictopol.substack.com/p/our-braini...
erictopol.substack.com/p/our-braini...
August 4, 2025 at 9:09 PM
One in 4 people carry one copy of the APOE4 allele, the strongest known genetic risk factor for Alzheimer's disease. We've just learned how that risk is mediated—the immune system
erictopol.substack.com/p/our-braini...
erictopol.substack.com/p/our-braini...