@drkbretz.bsky.social
Reposted
Keep this in mind as we start seeing more and more large scale outages from AWS, Cloudflare, Github, etc. These are the companies hoping to increasingly automate their systems with AI
![https://en.wikipedia.org/wiki/Automation
Paradox of automation
edit
The paradox of automation says that the more efficient the automated system, the more crucial the human contribution of the operators. Humans are less involved, but their involvement becomes more critical. Lisanne Bainbridge, a cognitive psychologist, identified these issues notably in her widely cited paper "Ironies of Automation."[49] If an automated system has an error, it will multiply that error until it is fixed or shut down. This is where human operators come in.[50] A fatal example of this was Air France Flight 447, where a failure of automation put the pilots into a manual situation they were not prepared for.[51]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:byjjq67p7iau6qufzjmizpbn/bafkreie4ootzzyowpylsxjg7gxsp63iujxh4qceuuxxhwm63yrm2qffa4e@jpeg)
November 18, 2025 at 9:37 PM
Keep this in mind as we start seeing more and more large scale outages from AWS, Cloudflare, Github, etc. These are the companies hoping to increasingly automate their systems with AI
Reposted
Masks, sound, speech, and accessibility, a thread! 🧵
I'm a professor. I teach in a mask. I do math with researchers and students with hearing and auditory processing disabilities. This is a thread on my solution for lip reading and audio quality all in one.
I'm a professor. I teach in a mask. I do math with researchers and students with hearing and auditory processing disabilities. This is a thread on my solution for lip reading and audio quality all in one.
January 29, 2025 at 9:41 PM
Masks, sound, speech, and accessibility, a thread! 🧵
I'm a professor. I teach in a mask. I do math with researchers and students with hearing and auditory processing disabilities. This is a thread on my solution for lip reading and audio quality all in one.
I'm a professor. I teach in a mask. I do math with researchers and students with hearing and auditory processing disabilities. This is a thread on my solution for lip reading and audio quality all in one.
Reposted
Harvard Psychiatrist Says Mental Illness Starts in Your Cells #Science #HealthandMedicine #MentalHealth #MentalHealthAwareness #CellBiology #Psychiatry
Harvard Psychiatrist Says Mental Illness Starts in Your Cells
Groundbreaking research is revealing that mental illness may start deep within the brain’s cells, where problems in energy production disrupt how neurons function and communicate. This shift in understanding...
purescience.news
October 25, 2025 at 9:45 PM
Harvard Psychiatrist Says Mental Illness Starts in Your Cells #Science #HealthandMedicine #MentalHealth #MentalHealthAwareness #CellBiology #Psychiatry
Reposted
Trazodone is very effective at improving sleep quality in #depression, concludes new review:
www.ncbi.nlm.nih.gov/pubmed/41081...
That’s something we can’t say for most antidepressants (serotonergics can make sleep worse), nor for most sleep meds (orexins are an exception).
#psychiatry #pmhnp
www.ncbi.nlm.nih.gov/pubmed/41081...
That’s something we can’t say for most antidepressants (serotonergics can make sleep worse), nor for most sleep meds (orexins are an exception).
#psychiatry #pmhnp
October 25, 2025 at 12:02 PM
Trazodone is very effective at improving sleep quality in #depression, concludes new review:
www.ncbi.nlm.nih.gov/pubmed/41081...
That’s something we can’t say for most antidepressants (serotonergics can make sleep worse), nor for most sleep meds (orexins are an exception).
#psychiatry #pmhnp
www.ncbi.nlm.nih.gov/pubmed/41081...
That’s something we can’t say for most antidepressants (serotonergics can make sleep worse), nor for most sleep meds (orexins are an exception).
#psychiatry #pmhnp
Reposted
I haven’t seen anyone talk about how Jane Doe - an Epstein survivor - just sued the Bank of New York Mellon for funding Epstein and failing to file a Suspicious Activity Report. A Mellon heir is the one who gave $130M to pay the troops. Seems bribey to me.
October 25, 2025 at 5:07 PM
I haven’t seen anyone talk about how Jane Doe - an Epstein survivor - just sued the Bank of New York Mellon for funding Epstein and failing to file a Suspicious Activity Report. A Mellon heir is the one who gave $130M to pay the troops. Seems bribey to me.
Reposted
Cancer is striking millennials younger than ever.
Possible culprits: ultra-processed food, toxic chemicals, microplastics, sleepless screens. Modern life is rewriting our biology. shorturl.at/Zhmkr #BlueSky #MedSky #NewsSky #EMSky #SciSky #IDSky #PedsSky #NurseSky #ObSky
Possible culprits: ultra-processed food, toxic chemicals, microplastics, sleepless screens. Modern life is rewriting our biology. shorturl.at/Zhmkr #BlueSky #MedSky #NewsSky #EMSky #SciSky #IDSky #PedsSky #NurseSky #ObSky
What researchers suspect may be fueling cancer among millennials
Studies suggest modern life may be fueling the rise of cancer in younger adults, with factors like ultra-processed foods and chemicals under scrutiny.
shorturl.at
September 29, 2025 at 5:55 PM
Reposted
Reposted
Yes. I have been practicing law for 40 years. I had the best Con Law teachers at UVA law school. But I can find no evidence of any unifying theory describing how this Court has ruled except to say that they have decided to discard the Constitution and anoint Trump dictator.
September 8, 2025 at 8:42 PM
Yes. I have been practicing law for 40 years. I had the best Con Law teachers at UVA law school. But I can find no evidence of any unifying theory describing how this Court has ruled except to say that they have decided to discard the Constitution and anoint Trump dictator.
Reposted
September 8, 2025 at 6:46 PM
Reposted
This. Thread.
August 28, 2025 at 4:00 AM
This. Thread.
Reposted
So we're not going to vaccinate kids this year. Ofc we're not going to mask or put HEPA filters in classrooms.
In a class of 33, every kid will get COViD at least once.
Every case results in cognitive impairment.
At least 3 kids will develop Long Covid. (1:11 is current thinking)
In a class of 33, every kid will get COViD at least once.
Every case results in cognitive impairment.
At least 3 kids will develop Long Covid. (1:11 is current thinking)
August 28, 2025 at 3:53 AM
So we're not going to vaccinate kids this year. Ofc we're not going to mask or put HEPA filters in classrooms.
In a class of 33, every kid will get COViD at least once.
Every case results in cognitive impairment.
At least 3 kids will develop Long Covid. (1:11 is current thinking)
In a class of 33, every kid will get COViD at least once.
Every case results in cognitive impairment.
At least 3 kids will develop Long Covid. (1:11 is current thinking)
Reposted
The teacher will have Covid at least once, with some degree of cognitive impairment and a higher risk of Long Covid and/or death.
COVID killed more than 47K Americans last year. Some 4 million of us have been disabled by Long Covid.
This is insanity. Madness.
COVID killed more than 47K Americans last year. Some 4 million of us have been disabled by Long Covid.
This is insanity. Madness.
August 28, 2025 at 4:02 AM
The teacher will have Covid at least once, with some degree of cognitive impairment and a higher risk of Long Covid and/or death.
COVID killed more than 47K Americans last year. Some 4 million of us have been disabled by Long Covid.
This is insanity. Madness.
COVID killed more than 47K Americans last year. Some 4 million of us have been disabled by Long Covid.
This is insanity. Madness.
Reposted
Elevated systemic inflammation (CRP) is one pathway through which heightened vigilance may contribute to CVD risk for African Americans adults.
Free to read for the week: journals.lww.com/bsam/fulltex...
#disparities #psychscisky #healthpsych #healthdisparities #affectivescience
Free to read for the week: journals.lww.com/bsam/fulltex...
#disparities #psychscisky #healthpsych #healthdisparities #affectivescience
Vigilance and Systemic Inflammation Among Middle-Aged to... : Biopsychosocial Science and Medicine
, threats related to discrimination), has previously been linked to markers of CVD risk among African Americans. However, the link between vigilance and inflammation remains underexplored in this popu...
journals.lww.com
August 27, 2025 at 10:43 PM
Elevated systemic inflammation (CRP) is one pathway through which heightened vigilance may contribute to CVD risk for African Americans adults.
Free to read for the week: journals.lww.com/bsam/fulltex...
#disparities #psychscisky #healthpsych #healthdisparities #affectivescience
Free to read for the week: journals.lww.com/bsam/fulltex...
#disparities #psychscisky #healthpsych #healthdisparities #affectivescience
Reposted
Are vaccines safe? Let’s ask a guy who has put live animals in a blender to make food for his hawks and injects an illicit tanning drug that the pharmaceutical industry chose not to try to take to market for humans because it caused sexual aggression in rodents.
Are vaccines safe? Let's ask this guy who sounds like a dying refrigerator compressor
August 28, 2025 at 4:00 AM
Are vaccines safe? Let’s ask a guy who has put live animals in a blender to make food for his hawks and injects an illicit tanning drug that the pharmaceutical industry chose not to try to take to market for humans because it caused sexual aggression in rodents.
Reposted
#MedSky #Covid The neat split between “people with long COVID” and “everyone else” never did line up with clinical realities. Truly never-infected people are now rare. We’re walking around with more inflammation, and with immune systems that don’t work quite as well as they did in the beforetime
Why scientists are rethinking the immune effects of SARS-CoV-2
“Immunity debt,” a theory to explain the global surge in non-covid infections since pandemic restrictions were lifted, is increasingly being challenged by emerging evidence. Nick Tsergas reports
Myco...
tinyurl.com
August 28, 2025 at 3:45 AM
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From CDC: How to get a 2025 Covid shot. "Physical inactivity" for the win! (Although I am plenty old enough to qualify, anyway.) Question for #medsky, including pharmacists: how long will my younger relatives have to sit quietly, to qualify for a shot?
Hang onto this image of CDC's full list of underlying conditions tied to severe risk of COVID.
If you're an adult aged 18-64, RFK Jr. is now making you show some proof of one of these underlying conditions in order to get a COVID vaccine.
If you're an adult aged 18-64, RFK Jr. is now making you show some proof of one of these underlying conditions in order to get a COVID vaccine.
August 28, 2025 at 3:49 AM
From CDC: How to get a 2025 Covid shot. "Physical inactivity" for the win! (Although I am plenty old enough to qualify, anyway.) Question for #medsky, including pharmacists: how long will my younger relatives have to sit quietly, to qualify for a shot?
Reposted
#MedSky "Studies in mice suggest that gene-editing technology, which has shown promise in treating diseases of the blood, liver and eyes, could also treat devastating brain disorders. The targets of the treatment are mutations that can cause neurological conditions such as Huntington’s disease."
Brain editing now ‘closer to reality’: the gene-altering tools tackling deadly disorders
Stunning results in mice herald gene-editing advances for neurological diseases.
tinyurl.com
August 28, 2025 at 3:49 AM
#MedSky "Studies in mice suggest that gene-editing technology, which has shown promise in treating diseases of the blood, liver and eyes, could also treat devastating brain disorders. The targets of the treatment are mutations that can cause neurological conditions such as Huntington’s disease."
Reposted
Donald Trump has no power over states as to how they conduct elections.
None.
None.
August 18, 2025 at 9:23 PM
Donald Trump has no power over states as to how they conduct elections.
None.
None.
Reposted
America Is Abandoning One of the Greatest Medical Breakthroughs
MRNA saved 20M lives, a million+ in US, reduced hospitalization & deaths, lowered long covid risk
mRNA
can be adapted for new viruses & is being tested for cancer vaccines, autoimmune therapies -
www.nytimes.com/2025/08/18/o...
MRNA saved 20M lives, a million+ in US, reduced hospitalization & deaths, lowered long covid risk
mRNA
can be adapted for new viruses & is being tested for cancer vaccines, autoimmune therapies -
www.nytimes.com/2025/08/18/o...
Opinion | America Is Abandoning One of the Greatest Medical Breakthroughs
www.nytimes.com
August 18, 2025 at 1:42 PM
America Is Abandoning One of the Greatest Medical Breakthroughs
MRNA saved 20M lives, a million+ in US, reduced hospitalization & deaths, lowered long covid risk
mRNA
can be adapted for new viruses & is being tested for cancer vaccines, autoimmune therapies -
www.nytimes.com/2025/08/18/o...
MRNA saved 20M lives, a million+ in US, reduced hospitalization & deaths, lowered long covid risk
mRNA
can be adapted for new viruses & is being tested for cancer vaccines, autoimmune therapies -
www.nytimes.com/2025/08/18/o...
Reposted
Hallmarks of brain aging from a comprehensive single-cell sequencing of 1.2 million cells
Specific cell-type pattern, role of immune response, inflammation, and a potential hypothalamus (near 3rd ventricle) hot spot for aging
www.nature.com/articles/s41... @nature.com @alleninstitute.bsky.social
Specific cell-type pattern, role of immune response, inflammation, and a potential hypothalamus (near 3rd ventricle) hot spot for aging
www.nature.com/articles/s41... @nature.com @alleninstitute.bsky.social
January 1, 2025 at 4:47 PM
Hallmarks of brain aging from a comprehensive single-cell sequencing of 1.2 million cells
Specific cell-type pattern, role of immune response, inflammation, and a potential hypothalamus (near 3rd ventricle) hot spot for aging
www.nature.com/articles/s41... @nature.com @alleninstitute.bsky.social
Specific cell-type pattern, role of immune response, inflammation, and a potential hypothalamus (near 3rd ventricle) hot spot for aging
www.nature.com/articles/s41... @nature.com @alleninstitute.bsky.social
Reposted
Our assessment of a person's epigenetic ("biological") age has been centered on DNA methylation. A new report shows that a set of 7 histone markers has comparable accuracy and also uncovers new pathways of aging biology
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
January 1, 2025 at 8:36 PM
Our assessment of a person's epigenetic ("biological") age has been centered on DNA methylation. A new report shows that a set of 7 histone markers has comparable accuracy and also uncovers new pathways of aging biology
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted
A new study this week showed how the most common blood test performed-—the CBC, complete blood count—contains a treasure chest of information that we are missing in reporting out to patients and doctors.
erictopol.substack.com/p/your-lab-t...
erictopol.substack.com/p/your-lab-t...
December 14, 2024 at 7:55 PM
A new study this week showed how the most common blood test performed-—the CBC, complete blood count—contains a treasure chest of information that we are missing in reporting out to patients and doctors.
erictopol.substack.com/p/your-lab-t...
erictopol.substack.com/p/your-lab-t...
Reposted
The XEC variant continues to show growth advantage in the latest US genomic SARS-CoV-2 surveillance, accounting for 44% of new cases
covid.cdc.gov/covid-data-t...
covid.cdc.gov/covid-data-t...
December 6, 2024 at 3:33 PM
The XEC variant continues to show growth advantage in the latest US genomic SARS-CoV-2 surveillance, accounting for 44% of new cases
covid.cdc.gov/covid-data-t...
covid.cdc.gov/covid-data-t...
Reposted
Vaccination significantly reduced #LongCovid in children and adolescents among ~300,000 kids and teens
www.thelancet.com/journals/ecl...
www.thelancet.com/journals/ecl...
December 7, 2024 at 2:39 PM
Vaccination significantly reduced #LongCovid in children and adolescents among ~300,000 kids and teens
www.thelancet.com/journals/ecl...
www.thelancet.com/journals/ecl...