Lightnews — Scholar-powered news

Meng Wang @drmengwang.bsky.social · Sep 8

Our lab road trip to #EMGS2025 at Rochester NY. Thank you to @emgsus.bsky.social for travel awards and poster presentations by postdoc Chris Mellor, grads Brandon James and Nick Cheng. A friendly and inviting community to bring trainees!

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Meng Wang @drmengwang.bsky.social · Aug 21

New publication from our lab! It was really fun writing this review @jcb.org with my postdoc Dr. Chris Mellor and graduate student Elisabeth Larson. We explore how folate deficiency trigger DNA damage that disrupt genome stability.

Journal of Cell Biology @jcb.org · Aug 18

New review: Mellor, Larson, and @drmengwang.bsky.social discuss the molecular mechanisms of mammalian genomic instability arising from folate deficiency and how this impacts genome biology in health and disease. rupress.org/jcb/article/...

#CellMetabolism

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Meng Wang @drmengwang.bsky.social · May 26

Cornell NCAA 2025 D1 Champions! 13-10 Win over Maryland. What a game! @cornelluniversity.bsky.social @ncaa.bsky.social

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Meng Wang @drmengwang.bsky.social · May 23

Many congratulations to Saeideh Azad, our talented Cornell undergraduate student who is graduating today @cornelluniversity.bsky.social. Saeideh has done a tremendous job working in our lab! We wish her all the best in her future endeavours!

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Meng Wang @drmengwang.bsky.social · May 1

Many congratulations Stephanie! Looking forward to the discoveries from the Xie lab!

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Meng Wang @drmengwang.bsky.social · Apr 26

Ok #AACR25, I’m truly impressed. A live sign-language interpreter translating Inigo’s @imartincorena.bsky.social plenary talk on somatic tissue mutational landscape. I want to learn the sign for ‘clonal’.

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Meng Wang @drmengwang.bsky.social · Apr 26

Exciting talk #AACR2025 @theaacr.bsky.social from my colleague and friend Dr. Karuna Ganesh! insights into why colon cancer is rising in young. A cool DNA damage mechanism! @karunamdphd.bsky.social @mskcancercenter.bsky.social

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Meng Wang @drmengwang.bsky.social · Apr 9

Many congratulations to our newest PhD student Emma Kosmeder @cornelluniversity.bsky.social for achieving an Honorable Mention in this year’s #NationalScienceFoundation GRFP! Considering only 1000 GRFP awarded this yr versus >2000 awards in past yrs, I am so proud to be mentoring Emma in her PhD.

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Meng Wang @drmengwang.bsky.social · Apr 9

Absolute delight and privilege to host Dr. Anna Beaudin @beaudinlab.bsky.social from @utah.edu. Very exciting work on fetal folate🥑metabolism rewiring 🩸blood stem cells. Thank you for visiting Cornell and passing your wisdom to our trainees and assistant profs!

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Reposted by Meng Wang

Rosado lab @rosadolab.bsky.social · Mar 27

Thrilled to share our latest work. Great collab with Costanzo, Masson, Freire and Reyes' labs. Congrats to María José and coauthors

HMCES corrupts replication fork stability during base excision repair in homologous recombination–deficient cells | Science Advances www.science.org/doi/10.1126/...

HMCES corrupts replication fork stability during base excision repair in homologous recombination–deficient cells

HMCES binding to nascent DNA blocks replication and kills homologous recombination–deficient cancer cells.

www.science.org

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Meng Wang @drmengwang.bsky.social · Mar 28

Congratulations Rosado lab! Great to see this work out in print!

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Meng Wang @drmengwang.bsky.social · Mar 22

Many congratulations!

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Reposted by Meng Wang

Sarah Caddy @drsarahcaddy.bsky.social · Mar 21

The maternal antibody paradox: how are these antibodies both good and bad? Excited to share our new insights for rotavirus vaccines
www.biorxiv.org/content/10.1...

Mechanisms of maternal antibody interference to rotavirus vaccination

Maternal antibodies (MatAbs) are transferred transplacentally during pregnancy and through breast milk after birth to provide protection whilst the neonatal immune response is immature. However, MatAb...

www.biorxiv.org

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Meng Wang @drmengwang.bsky.social · Feb 24

During this chaotic time, I take satisfaction doing little things that improve the lab. Today I rigged an argon gas blower for our chemical hood. #labrat

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Reposted by Meng Wang

Scott Delaney @scott-delaney.bsky.social · Feb 21

NIH indirects case update:

Hearing ongoing now, and I'll try to live tweet some notable exchanges.

Prior to more detailed arguments, Judge Kelley starts off with a few point questions to both sides:

(I'm paraphrasing here)

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Meng Wang @drmengwang.bsky.social · Feb 14

Many congratulations Will! Beautiful work!

Reposted by Meng Wang

Immunominutes @cindyleifer.bsky.social · Feb 10

It’s day 1 of the cut to NIH indirects and universities are scrambling to adapt. I’m going to post a series of videos on all the things I take for granted, but are both vital to research and covered by indirects for research grants.

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Reposted by Meng Wang

Carl T. Bergstrom @carlbergstrom.com · Feb 8

1. Today the NIH director issued a new directive slashing overhead rates to 15%.

I want to provide some context on what that means and why it matters.

grants.nih.gov/grants/guide...

NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD

grants.nih.gov

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Reposted by Meng Wang

Alt NIH Bluesky 🧪 @altnih4science.bsky.social · Feb 7

🚨RED ALERT for 🧪:

The Trump NIH just gashed indirect costs. This is a direct attack on universities.

“Pursuant to this Supplemental Guidance, there will be a standard rate of 15% across all NIH grants for indirect costs.” 😮

Just a devastating Friday night news dump. #scicomm #academicaky

Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
Notice Number:
NOT-OD-25-068
Key Dates
Release Date:
February 7, 2025

Related Announcements
None

Issued by
Office of The Director, National Institutes of Health (OD)

Purpose

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Meng Wang @drmengwang.bsky.social · Feb 4

Yes, doubleplusgood. Me writing my untruth grant in 2025.

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Meng Wang @drmengwang.bsky.social · Dec 20

Merry Christmas and Happy New Year from the Wang Lab! I’m so thankful to my lab, discussing and doing science with you guys is the best part of the job!

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Meng Wang @drmengwang.bsky.social · Dec 12

Many congratulations Ana and team!

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Reposted by Meng Wang

Ana Tufegdzic Vidakovic @anatv.bsky.social · Dec 11

The first paper from our lab is online! A wonderful collaboration with @scottbscience.bsky.social lab. We discover that Pol II is extensively regulated by Ubiquitin at the beginning of the transcription cycle!
www.cell.com/molecular-ce...

CRL3ARMC5 ubiquitin ligase and Integrator phosphatase form parallel mechanisms to control early stages of RNA Pol II transcription

Cacioppo, Gillis, Shlamovitz, Zeller, et al. show that CRL3ARMC5 ubiquitylates RNA Pol II at early stages of transcription as part of a major homeostatic RNA Pol II turnover mechanism. CRL3ARMC5 and the Integrator phosphatase act as complementary pathways, monitoring the quantity and quality of RNA Pol II complexes before they are licensed into elongation.

www.cell.com

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Meng Wang @drmengwang.bsky.social · Dec 2

Many congratulations to @rockefelleruniv.bsky.social MDPhD student and soon-to-be Dr Nicky Blobel from Smogorzewska Lab for passing his PhD defense today! It was my pleasure to be your external examiner and share our passion on endogenous DNA 🧬damage!

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Meng Wang @drmengwang.bsky.social · Nov 28

Can someone please rank my emotional stability compared to all undergraduates in their institution? I think my lab deserves to know.

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