Lightnews — Scholar-powered news

Dimitry Tegunov @dtegunov.bsky.social · 4d

It took me several weeks to notice how perfect this arrangement was

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Dimitry Tegunov @dtegunov.bsky.social · 9d

What protein is that?

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Dimitry Tegunov @dtegunov.bsky.social · 14d

The things Apple will do to procrastinate improving Siri

Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 14d

iFold, sorry, SimpleFold, by Apple

arxiv.org/html/2509.18...

SimpleFold: Folding Proteins is Simpler than You Think

arxiv.org

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Dimitry Tegunov @dtegunov.bsky.social · 14d

Ugh, I'm starting to get spam texts with em dashes

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Reposted by Dimitry Tegunov

Guenter Resch @nexperion.net · 15d

Happy to announce "Technical Innovations Using #SerialEM: A Community Meeting", a new format of hybrid meeting David Mastronarde and I are organizing in April 2026. For more info, a preliminary list of speakers, pre-registration etc. visit
www.nexperion.net/semcm2026

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Dimitry Tegunov @dtegunov.bsky.social · 15d

The North Bay is so packed with Porsches that the non-Porsches (Norsches?) are the real exotics there

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Dimitry Tegunov @dtegunov.bsky.social · 18d

I think O1 is initiated by the future employer more often than not. It costs a lot more in lawyer fees, which, to my understanding, is why universities rarely sponsor it. Some postdocs would pass the professional visibility requirement, but it would be hard to argue the flashiness of their position.

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Dimitry Tegunov @dtegunov.bsky.social · 18d

Is H1B prevalent below faculty level? Many faculty hires would easily qualify for O1, and the legal costs for that are well below 100k

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Dimitry Tegunov @dtegunov.bsky.social · 18d

Physicists (and, more recently, techies) are kind of famous for underestimating the effort required for understanding biology. Sure it's easy to look once all the work to make a result visible has been done.

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Dimitry Tegunov @dtegunov.bsky.social · 18d

Sounds like it's just an incentive for more lobbyism and campaign donations

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Dimitry Tegunov @dtegunov.bsky.social · 25d

Important to remember the theoretical size limit is based on assumptions and a model that may or may not be complete. It isn't some indisputable universal truth.

Harry Low’s Lab @lowlab.bsky.social · 25d

‘We expect that this approach may be useful for cryo-EM analysis of other small particles near or below the theoretical size limit.’ 🤯

Oli Clarke @olibclarke.bsky.social · 26d

This one is a bit of a departure from the usual and definitely a work in progress!

We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below.

Read on for details... 1/x

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Dimitry Tegunov @dtegunov.bsky.social · 25d

I'm curious if it's the SGD with minibatches helping here, or just the very slow, controlled increase in assumed resolution.

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Dimitry Tegunov @dtegunov.bsky.social · 25d

Very interesting! Any comments from Ali?

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Dimitry Tegunov @dtegunov.bsky.social · Sep 1

A fun introduction to problems arising from having to do Cartesian things on a sphere: www.bowerbyte.com/posts/blocky...

Blocky Planet — Making Minecraft Spherical

Discover the unique design challenges of creating a spherical planet out of Minecraft-like blocks.

www.bowerbyte.com

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Dimitry Tegunov @dtegunov.bsky.social · Aug 21

You're absolutely right!

Dimitry Tegunov @dtegunov.bsky.social · Aug 15

K-Pop Demon Hunters OST playing on the radio? Cool!

Dimitry Tegunov @dtegunov.bsky.social · Aug 7

I think they were added in the late 2000s to detects falls and quickly park the hard drive heads. At least my old Thinkpad had one for this reason. The hard drive is gone, but the accelerometer remains

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Dimitry Tegunov @dtegunov.bsky.social · Aug 7

I just found out the latest version of MacOS finally implements the motion cue dots iOS has had for a few years now, and it's doing wonders for me when I need to use my laptop on bus rides

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Dimitry Tegunov @dtegunov.bsky.social · Aug 1

I wouldn't blame it

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Dimitry Tegunov @dtegunov.bsky.social · Aug 1

I don't know what cursed token sequence puts Claude into stupid mode, but it's impossible to recover from it and you have to start a new conversation

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Dimitry Tegunov @dtegunov.bsky.social · Jul 20

First flight lesson survived!

Dimitry standing in front of the plane the instructor didn't let him crash despite Dimitry's best efforts

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Dimitry Tegunov @dtegunov.bsky.social · Jul 1

After a lot of averaging, but not reconstructions from raw data

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Dimitry Tegunov @dtegunov.bsky.social · Jul 1

Whoever gets the resolution of raw tomograms to <10 Å within the sampled parts of Fourier space would probably deserve a Nobel. Or they'd get one anyway for the crazy new physics they discovered to achieve that.

Bogdan Toader @btoader.com · Jul 1

“Achieving individual tomograms of cells where any features are at 10 Å resolution or better is well-beyond both current capabilities and reasonable predictions of future improvements.”
:(

Josh Dickerson @joshdcryoem.bsky.social · Jun 28

Check out our recent review discussing the merits of tilt series vs single micrographs for in situ cryo-EM! www.sciencedirect.com/science/arti...

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Dimitry Tegunov @dtegunov.bsky.social · Jun 10

Mine would start with W

Dimitry Tegunov @dtegunov.bsky.social · May 31

I had a dream last night where some online store had the 5090 FE in stock at MSRP. It was a happy dream 🥹

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