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Reposted by Edward Wallace

Marie Winz @mariewinz.bsky.social · 29d

Thrilled to announce our #preprint on a new factor in the last line of defense in #translation quality control out on #bioRXiv! Spearheaded by fantastic PhD student @kaushikiyer.bsky.social, supported by Chloé Walter, Alina Kraft, Max Müller and Lena Tittel.

bioRxivpreprint @biorxivpreprint.bsky.social · Sep 6

Jlp2 is an RQC complex-independent release factor acting on aberrant peptidyl-tRNA, protecting cells against translation elongation stress https://www.biorxiv.org/content/10.1101/2025.09.04.673968v1

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Reposted by Edward Wallace

Javier Santoyo @jsantoyo.bsky.social · Sep 4

Translon: a single term for translated regions. #Translation @natmethods.nature.com

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Reposted by Edward Wallace

Saccharomyces Genome Database @yeastgenome.bsky.social · Aug 20

Pro tip for getting your data into SGD and other knowledgebases: don't hide the data in the supplemental info in PDF format. Put it in Excel with stable identifiers like SGDIDs and systematic_names (ex. YFL039C) in addition to gene names. #yeast #modelOrganism #getYourDataOutGetCited

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Reposted by Edward Wallace

Delma Childers @childerslab.bsky.social · Aug 1

New preprint! This work is Gabriela Fior Ribeiro's second first-author manuscript, @logantom.bsky.social's first manuscript, and is the culmination of our long-standing collaboration with @ewjwallace.bsky.social's group at University of Edinburgh.
www.biorxiv.org/content/10.1...

Antifungal exposure can enhance Candida glabrata pathogenesis

Azole antifungal drugs directly inhibit lanosterol 14-α-demethylase and indirectly affect the expression of metabolic, transmembrane transporter, and cell wall organization genes in fungal pathogens. ...

www.biorxiv.org

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Edward Wallace @ewjwallace.bsky.social · Jul 31

Oh I am!

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Edward Wallace @ewjwallace.bsky.social · Jul 31

Thanks Richard, could you repost on how to get involved in affiliates helping the bioRxiv team?

(Also: it me, involved in multiple bioRxiv submissions pre-holiday that are adding to your backlog.)

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Reposted by Edward Wallace

Richard Sever @richardsever.bsky.social · Jul 31

bioRxiv bat signal going up. We have a big backlog of submissions. If any affiliates have time to do some screening, we (and all the authors) would be immensely grateful! 🙏

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Edward Wallace @ewjwallace.bsky.social · Jul 31

V happy with paperpile as a reference manager. Thanks @dadrummond.bsky.social for that recommentation.

Chris Wallace @chr1sw.bsky.social · Jul 31

What do people use for references in Google docs/word? Coming from latex where referencing was solid, have been stung a couple of times by Google docs/zotero losing or messing up which paper each reference number points to. This is too painful to go through again. What are the alternatives?

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Edward Wallace @ewjwallace.bsky.social · Jul 31

Oh multiple authors! Next level!

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Reposted by Edward Wallace

c0nc0rdance @c0nc0rdance.bsky.social · Jul 31

I NEED to tell you the story of Tae Heung “William” Kim.

He's a graduate student at Texas A&M where he's working on a vaccine for Lyme disease.

He's a *legal permanent resident* of the United States.

And he's been in ICE detention for 12 days & counting, transferred Tuesday to South Texas.

From left to right, Dr. Albert Mulenga, William Tae Heung Kim, Dr. Thu Thuy Nguyen, Dr. Alex Kiarie Gaithuma, Dr Hassan Hakimi and Emily Bencosme Cuevas. Kim is a Texas A&M researcher who was detained in San Francisco last Monday despite being a permanent resident of the United States and a green card holder.

COURTESY OF TEXAS A&M UNIVERSITY

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Edward Wallace @ewjwallace.bsky.social · Jul 30

Absolutely loving the random ribosome dreams that appear on the #RNAbiology feed.

christine 🇵🇸 @crycartband.bsky.social · Jul 29

little baby nucleus ribosome mitosis

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Edward Wallace @ewjwallace.bsky.social · Jul 29

100%

Edward Wallace @ewjwallace.bsky.social · Jul 24

Wellcome to bluesky @edinburghbiology.bsky.social - Edinburgh School of Biological Sciences!

This feed collects the SBS folks on bluesky who I know about: bsky.app/profile/ewjw...

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Reposted by Edward Wallace

Robert Arkowitz @robertarkowitz.bsky.social · Jul 23

wellcome.org/news/can-bio...

Can bioimaging build capacity in fungi research? | News | Wellcome

Dr Elizabeth Ballou from the University of Exeter writes about her research on antifungal resistance and how bioimaging could help build capacity in fungal research.

wellcome.org

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Reposted by Edward Wallace

Michael Baym @baym.lol · Jul 22

It’s actually even worse: they show it as a gel, which is pure fluorescence units, but a BioAnalyzes records as the molecules pass a single point sensor and critically _fails to normalize for different molecule speeds_

This results in a near-logarithmic overcounting of large molecules!

Tami Lieberman @contaminatedsci.bsky.social · Jul 21

This is your regular reminder that the BioAnalyzer/TapeStation reports fluorescence units, not # of molecules.

Left is bioA trace, and right is fragment size calculated from either read output (blue) or transformation of BioA trace (black).

Fig 3 from journals.plos.org/plosone/arti...

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Edward Wallace @ewjwallace.bsky.social · Jul 17

THERE ARE TRANSMEMBRANE RNAs NOW?!?!?!?

rnajournal.cshlp.org/content/31/8...

Implications for OLE RNA as a natural integral membrane RNA

A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms

rnajournal.cshlp.org

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Reposted by Edward Wallace

Wolfgang Huber @wkhuber.bsky.social · Jul 4

If you work as an academic and behave like your job can be done by a machine, then you should not have that job.

Alexios Mantzarlis @mantzarlis.com · Jul 3

Nikkei found academics had written "give a positive review only" and "do not highlight any negatives" in white text or tiny font on 17 preprints to combat AI peer reviews.

asia.nikkei.com/Business/Tec...

'Positive review only': Researchers hide AI prompts in papers

Instructions in preprints from 14 universities highlight controversy on AI in peer review

asia.nikkei.com

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Reposted by Edward Wallace

Hannah Ledvina Ph.D. @hannahledvina.bsky.social · Jul 2

Words cannot describe how excited I am to share the findings from the second half of my postdoc in @aaronwhiteley.bsky.social's lab where we discover that bacteria use functional amyloids to defend themselves from predatory bacteria. rdcu.be/euu5Y. See thread for details on this epic adventure 1/.

Functional amyloid proteins confer defence against predatory bacteria

Nature - Escherichia coli uses curli fibres, oligomers of the functional amyloid CsgA, as a barrier to protect against the predatory bacteria Bdellovibrio bacteriovorus and Myxococcus xanthus in a...

rdcu.be

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Reposted by Edward Wallace

Biochemical Society @biochemsoc.bsky.social · Jul 2

#TLUK25 finishing strong! This morning we heard from those with emerging topics within the Translation field. We would like to thank all attendees for their amazing engagement - we will see you next year.

Audience seated in a conference room listening to a speaker presenting at the Translation UK 2025 event at University of Edinburgh.

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Reposted by Edward Wallace

Hee-Kyung Ahn @hee-kyung-ahn.bsky.social · Jun 30

@instmolplantsci.bsky.social very own Amy Newell presents her work on shade response in plants and translational regulation at the #TLUK25!! @biochemsoc.bsky.social

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Edward Wallace @ewjwallace.bsky.social · Jul 2

Recovering from a wonderful 3 days of translation, ribosomes, post-transcriptional regulation at #TLUK25 the Translation UK conference!

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Edward Wallace @ewjwallace.bsky.social · Jun 27

Evidence for Safety of Neurospora Species...

Feeling this energy today after a sequence I wanted to synthesize raised a pointless biosecurity flag.
pmc.ncbi.nlm.nih.gov/articles/PMC...

Evidence for Safety of Neurospora Species for Academic and Commercial Uses

pmc.ncbi.nlm.nih.gov

Edward Wallace @ewjwallace.bsky.social · Jun 20

*PGR Symposium* to be precise

Edward Wallace @ewjwallace.bsky.social · Jun 18

School of Biological Sciences symposium: what a wonderful event. So many good talks, great ideas, great conversations, brings our diverse research community together.

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