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Reposted by Elana Fertig, PhD

PhysiCell Project. @physicell.bsky.social · Jul 29

Major PhysiCell paper in Cell using a new, intuitive model grammar to create complex multicellular systems models with "plain language" cell hypotheses! 🧪

@cellpress.bsky.social @cp-cell.bsky.social @mathcancer.bsky.social @fertiglab.bsky.social #mathonco #mathbio #abm #opensource

Paul Macklin @mathcancer.bsky.social · Jul 28

Really excited to share our new @cellpress.bsky.social Cell paper with @fertiglab.bsky.social and colleagues. 1/n

www.cell.com/cell/fulltex...

@jktgfoundation.bsky.social @itcrtraining.bsky.social @smbmathbiology.bsky.social #mathbio #mathonco @mathonco.bsky.social @deniswirtz.bsky.social

Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories

We developed a plain text modeling language—a cell behavior hypothesis grammar—to easily build virtual cell models and connect them to data, helping scientists to unlock the hidden dynamics of tissues...

www.cell.com

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Reposted by Elana Fertig, PhD

Paul Macklin @mathcancer.bsky.social · Jul 29

Excited for this @cp-cell.bsky.social article co-led by @fertiglab.bsky.social and Genevieve Stein-O'Brien, on creating a plain language "grammar" to easily write simulation models as virtual laboratories for complex systems like cancer.

Fully open access and open source! 🧪 #mathonco #mathbio

Cell - a Cell Press journal @cp-cell.bsky.social · Jul 25

Now online! Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories

Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories

We developed a plain text modeling language—a cell behavior hypothesis grammar—to easily build virtual cell models and connect them to data, helping scientists to unlock the hidden dynamics of tissues. We provide examples showing how to use them in virtual experiments exploring how cancer responds to the cells in its environment and how the brain forms layers in development.

dlvr.it

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Reposted by Elana Fertig, PhD

Paul Macklin @mathcancer.bsky.social · Jul 28

Really excited to share our new @cellpress.bsky.social Cell paper with @fertiglab.bsky.social and colleagues. 1/n

www.cell.com/cell/fulltex...

@jktgfoundation.bsky.social @itcrtraining.bsky.social @smbmathbiology.bsky.social #mathbio #mathonco @mathonco.bsky.social @deniswirtz.bsky.social

Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories

We developed a plain text modeling language—a cell behavior hypothesis grammar—to easily build virtual cell models and connect them to data, helping scientists to unlock the hidden dynamics of tissues...

www.cell.com

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Reposted by Elana Fertig, PhD

Edna Cukierman - Tumor Microenvironment @tme-caf-ecm.bsky.social · Apr 29

#AACR25 #AACR2025 @theaacr.bsky.social following the plenary session, at 10:15 in S105, we will showcase possible means to preventing cancer onset by intercepting its #TME
@fertiglab.bsky.social
#BarbaraVanderhyden and yours truly

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Reposted by Elana Fertig, PhD

University of Maryland School of Medicine @medschool.umaryland.edu · Apr 25

Researchers at UMSOM are pioneering a new approach to precision medicine by combining AI with mathematical modeling.🌟🔬

@fertiglab.bsky.social and @genomescience.bsky.social
colleagues share the importance of ethically sharing health data to ensure reproducible and trustworthy scientific outcomes.

2025 News - While AI Could Be the Game Changer in Predicting Health Outcomes It Should Not Be the Only Method | University of Maryland School of Medicine

bit.ly

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Reposted by Elana Fertig, PhD

Erna Magnúsdóttir @e-rna.bsky.social · Apr 22

Join our lab to study transcriptional regulation in mouse germ cells and embryonic stem cells at @haskoliislands.bsky.social in beautiful Reykjavík!
Apply here: tinyurl.com/34y6jcrd
#epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency

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Elana Fertig, PhD @fertiglab.bsky.social · Apr 20

I can't understand why foundation models are thought to be the source of "virtual cells". AI and foundation models are good for many things, but they seem far more likely to predict cell labels or phenotypic effects of perturbations than to trace cells in systems virtually.

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Reposted by Elana Fertig, PhD

Karen Attiah @karenattiah.bsky.social · Apr 17

Call it what it is: a race/ gender purge.

The Washington Post @washingtonpost.com · Apr 16

Thirty-eight of 43 experts cut last month from the boards that review the science and research that happens in laboratories at the National Institutes of Health are female, Black or Hispanic, according to an analysis by the chairs of a dozen of the boards.

Women, minorities fired in purge of NIH science review boards

Scientists, with expertise in fields that include mental health, cancer and infectious disease, typically serve five-year terms and were not given a reason for their dismissal.

www.washingtonpost.com

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Reposted by Elana Fertig, PhD

Nature Biotechnology @natbiotech.nature.com · Apr 16

Virtual cells for predictive immunotherapy - @fertiglab.bsky.social @genomescience.bsky.social go.nature.com/4jfqM3Y

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Elana Fertig, PhD @fertiglab.bsky.social · Apr 15

Proud of our new perspective describing the role of mathematical biology for immunotherapy www.nature.com/articles/s41... @natbiotech.nature.com

Virtual cells for predictive immunotherapy - Nature Biotechnology

Synergizing advances in artificial intelligence with mathematical modeling will improve our ability to computationally predict immunotherapy outcomes.

www.nature.com

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Elana Fertig, PhD @fertiglab.bsky.social · Apr 11

Any mamma of a kid with autism knows exactly where a quick claim of its cause / blame will go…..

Dr. Lucky Tran @luckytran.com · Apr 10

Science does not work like this. The only way you can set a timeline is if you have rigged the results in advance.

RFK Jr. says HHS will determine the cause of autism by September

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Elana Fertig, PhD @fertiglab.bsky.social · Apr 6

Omg!!!! So proud of my baby cousin!!!!!!

Musical Theatre Review @musicaltheatrer.bsky.social · Apr 6

No sinking feeling for Titanique tonight. The show currently running at the Criterion Theatre, has won the award for Best New Entertainment or Comedy Play! @olivierawards.bsky.social

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Reposted by Elana Fertig, PhD

David Basanta @cancerevo.org · Apr 4

Unexpected treat today @moffittnews.bsky.social Innovator's of Tomorrow symposium with Jeanette Johnson, working with @fertiglab.bsky.social and developing on @physicell.bsky.social to create an #ABM for #pancreatic #cancer forecasting

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Elana Fertig, PhD @fertiglab.bsky.social · Apr 5

So good to see you Rob!! Exited to be at the same institution again :)

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Reposted by Elana Fertig, PhD

Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · Mar 15

as I tell my Genetics class every year, this breakthrough is based on 70 years of NIH-funded, basic research, commercialized by biotech
bsky.app/profile/need...

Freeyore @mewefree.bsky.social · Mar 15

Looks like we've got a cure for sickle cell. www.cbsnews.com/newyork/news...

Long Island man is first in New York history to be cured of sickle cell anemia

A patient on Long Island is the first in New York to be cured of sickle cell anemia, doctors say.

www.cbsnews.com

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Elana Fertig, PhD @fertiglab.bsky.social · Mar 10

Homecoming seminar @ummedschool.bsky.social

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Elana Fertig, PhD @fertiglab.bsky.social · Mar 10

Thank you to the #EACR!

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Reposted by Elana Fertig, PhD

Johanna Joyce @johannajoyce.bsky.social · Mar 10

Cancer knows no borders, and setbacks in one part of the world can have lasting consequences for #patients everywhere

The #EACR, and all co-signing national #cancer societies & foundations, stand in solidarity and offer our full support to our friends and colleagues in the US

#StandUpForScience 🧪

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Reposted by Elana Fertig, PhD

Scott Johnson @scottjohnson.wtf · Mar 1

Cleveland on the Ukraine invasion anniversary

Photo of the upper floors of The Terminal Tower in Cleveland, lit in blue and gold on the anniversary of the Russian invasion of Ukraine

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Reposted by Elana Fertig, PhD

Jamie Carter @jctheresistance.demcast.com · Feb 28

I am ashamed to be an American today.

I stand with Ukraine.

I stand with Canada.

I stand with Panama.

I stand with Greenland.

I stand with Europe.

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Elana Fertig, PhD @fertiglab.bsky.social · Mar 1

My kids thoughts and our hearts to everyone at NOAA @benfertig.bsky.social

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Reposted by Elana Fertig, PhD

OpenCravat.bsky.social @opencravat.bsky.social · Feb 22

🧬 We Want Your Feedback! 🧬\

Do you use variant annotation software? We’re gathering insights from the genomics community to improve OpenCRAVAT and understand what features matter most to you.💡 Take this quick survey (it takes less than 2 minutes!): https://shorturl.at/iOvMt

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Elana Fertig, PhD @fertiglab.bsky.social · Feb 28

Heatbreaking. Absolutely heartbreaking

Dr. Larissa @rissarwx.bsky.social · Feb 27

All probationary federal employees at NOAA’s EMC that’s responsible for keeping all US weather model systems running have been fired with 1 hours notice. And that includes me and colleagues. We will not go quietly because we care about the NOAA mission to protect the public.

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Reposted by Elana Fertig, PhD

Cell Systems @cp-cellsystems.bsky.social · Feb 26

We asked J. Moffitt, M. Li, Q., K. Kanemaru, S. Teichmann, D. Dar, S. Itzkovitz, R. Vento-Tormo, @ltkagohara.bsky.social @itaiyanai.bsky.social @fertiglab.bsky.social @fabiantheis.bsky.social about bottlenecks facing Spatial Transcriptomics www.cell.com/cell-systems/abstract/S2405-4712(25)00033-X

What is the main bottleneck in deriving biological understanding from spatial transcriptomic profiling?

Image-based approaches to single-cell transcriptomics offer the exciting ability to directly image gene expression at the transcriptome scale within intact tissue slices, defining, discovering, and ma...

www.cell.com

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