Francisco Falcon
@ffalcon.bsky.social
Bioinformatics Enthusiast. I like transposons. PhD student at IMBA, part of Vienna BioCenter
Reposted by Francisco Falcon
Thrilled to share our new review in Current Opinion in Genetics & Development on TE driven innovation in gene regulation🤘. I am honored to be part of this with two major TE aficionados @cedricfeschotte.bsky.social and @trono-lab.bsky.social
#TEsky #TEworldwide
authors.elsevier.com/c/1m6MC,LqAZ...
#TEsky #TEworldwide
authors.elsevier.com/c/1m6MC,LqAZ...
November 15, 2025 at 5:23 PM
Thrilled to share our new review in Current Opinion in Genetics & Development on TE driven innovation in gene regulation🤘. I am honored to be part of this with two major TE aficionados @cedricfeschotte.bsky.social and @trono-lab.bsky.social
#TEsky #TEworldwide
authors.elsevier.com/c/1m6MC,LqAZ...
#TEsky #TEworldwide
authors.elsevier.com/c/1m6MC,LqAZ...
Reposted by Francisco Falcon
Grateful and excited to launch the Otsuki Regeneration Group at the Hubrecht Institute!
🔗 www.hubrecht.eu/research-gro...
We study how tissues regenerate - and use those principles to build 3D tissues in vitro.
Full announcement: www.linkedin.com/in/leo-otsuk...
@hubrechtinstitute.bsky.social
🔗 www.hubrecht.eu/research-gro...
We study how tissues regenerate - and use those principles to build 3D tissues in vitro.
Full announcement: www.linkedin.com/in/leo-otsuk...
@hubrechtinstitute.bsky.social
July 25, 2025 at 7:30 AM
Grateful and excited to launch the Otsuki Regeneration Group at the Hubrecht Institute!
🔗 www.hubrecht.eu/research-gro...
We study how tissues regenerate - and use those principles to build 3D tissues in vitro.
Full announcement: www.linkedin.com/in/leo-otsuk...
@hubrechtinstitute.bsky.social
🔗 www.hubrecht.eu/research-gro...
We study how tissues regenerate - and use those principles to build 3D tissues in vitro.
Full announcement: www.linkedin.com/in/leo-otsuk...
@hubrechtinstitute.bsky.social
Reposted by Francisco Falcon
Exactly two weeks left to submit your abstract to the EMBO Mobile Genome Workshop.
☝️this year we will select from abstracts 2 “long” talks to highlight last minute breakthrough from early career scientists. Apply! July 29th
☝️this year we will select from abstracts 2 “long” talks to highlight last minute breakthrough from early career scientists. Apply! July 29th
⏰ Abstract deadline for 'The mobile genome' is 29 July!
👉 https://s.embl.org/mge25-01-bl
Join us 4–7 Nov 2025 at EMBL Heidelberg (or online) to explore the impact of TEs across biology. 🧬🔍
⭐🧑🏼🔬 24 talks + 15 flash talks from posters – don't miss out!
#EMBOMobileGenome
👉 https://s.embl.org/mge25-01-bl
Join us 4–7 Nov 2025 at EMBL Heidelberg (or online) to explore the impact of TEs across biology. 🧬🔍
⭐🧑🏼🔬 24 talks + 15 flash talks from posters – don't miss out!
#EMBOMobileGenome
July 15, 2025 at 12:35 PM
Exactly two weeks left to submit your abstract to the EMBO Mobile Genome Workshop.
☝️this year we will select from abstracts 2 “long” talks to highlight last minute breakthrough from early career scientists. Apply! July 29th
☝️this year we will select from abstracts 2 “long” talks to highlight last minute breakthrough from early career scientists. Apply! July 29th
Reposted by Francisco Falcon
Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature Genetics
Activation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype c...
www.nature.com
July 9, 2025 at 10:05 AM
Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Reposted by Francisco Falcon
REFEREE 1: “I conclude with a simple, direct statement - this is the best paper I have read all year!”
#TransparentPeerReview
Co-evolving infectivity and expression patterns drive the diversification of endogenous retroviruses
@juliusbrennecke.bsky.social et al
www.embopress.org/doi/full/10....
#TransparentPeerReview
Co-evolving infectivity and expression patterns drive the diversification of endogenous retroviruses
@juliusbrennecke.bsky.social et al
www.embopress.org/doi/full/10....
June 6, 2025 at 2:18 PM
REFEREE 1: “I conclude with a simple, direct statement - this is the best paper I have read all year!”
#TransparentPeerReview
Co-evolving infectivity and expression patterns drive the diversification of endogenous retroviruses
@juliusbrennecke.bsky.social et al
www.embopress.org/doi/full/10....
#TransparentPeerReview
Co-evolving infectivity and expression patterns drive the diversification of endogenous retroviruses
@juliusbrennecke.bsky.social et al
www.embopress.org/doi/full/10....
Reposted by Francisco Falcon
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
May 21, 2025 at 3:05 PM
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
Reposted by Francisco Falcon
1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. 🧬
But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯
Our new study reveals how retrotransposons invade the germline directly from somatic cells.
www.biorxiv.org/content/10.1...
A short thread 🧵👇
But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯
Our new study reveals how retrotransposons invade the germline directly from somatic cells.
www.biorxiv.org/content/10.1...
A short thread 🧵👇
March 17, 2025 at 11:56 AM
1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. 🧬
But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯
Our new study reveals how retrotransposons invade the germline directly from somatic cells.
www.biorxiv.org/content/10.1...
A short thread 🧵👇
But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯
Our new study reveals how retrotransposons invade the germline directly from somatic cells.
www.biorxiv.org/content/10.1...
A short thread 🧵👇
My first post in bsky and my first pre-print as well. Hope you enjoy this brief highlight made by @alexdemendoza.bsky.social and team!
Breaking paradigms: Finding 6mA DNA methylation in eukaryotes
Francisco Falcon @ffalcon.bsky.social highlights research from @alexdemendoza.bsky.social and team on 6mA in eukaryotes.
#preprint #preLights
👀⤵️
prelights.biologists.com/highlights/a...
Francisco Falcon @ffalcon.bsky.social highlights research from @alexdemendoza.bsky.social and team on 6mA in eukaryotes.
#preprint #preLights
👀⤵️
prelights.biologists.com/highlights/a...
Adenine DNA methylation associated to transcription is widespread across eukaryotes - preLights
Breaking paradigms: Finding 6mA DNA methylation in eukaryotes.
prelights.biologists.com
January 15, 2025 at 2:35 PM
My first post in bsky and my first pre-print as well. Hope you enjoy this brief highlight made by @alexdemendoza.bsky.social and team!