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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · 1d

Congratulations to @volkerhaucke-lab.bsky.social for receiving the prestigious Reinhart Koselleck Grant by the @dfg.de (German Research Foundation) once again! 🎉

www.linkedin.com/feed/update/...

Another award for Volker Haucke, Director at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and Professor at Freie Universität Berlin: The Deutsche Forschungsgemeinschaft (DFG) -… ...

Another award for Volker Haucke, Director at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and Professor at Freie Universität Berlin: The Deutsche Forschungsgemeinschaft (DFG) - G...

www.linkedin.com

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · 15d

Congrats to Volker Haucke, Director at the Leibniz-FMP on being awarded the Ernst Schering Prize 2025 for his pioneering work on the function of signaling lipids that control how cells respond to hormones, nutrients and messengers.

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Reposted by Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)

Vince Arafiles @vincearafiles.bsky.social · 21d

🔥After years of hard work, it's finally out in @natchem.nature.com🔥 The Hackenberger group @fmp-berlin.de developed #🎯DarT-labeling, a #photocatalyticproximitylabeling method using deazaflavin - a ✅ biocompatible ✅ easily synthesized ✅ chemically benign #photocatalyst

www.nature.com/articles/s41...

Energy-transfer photoproximity labelling in live cells using an organic cofactor - Nature Chemistry

Current photoproximity labelling methods often require metal-based catalysts to map protein interactomes but, owing to their toxicity, they have limited intracellular applicability. A deazaflavin cofa...

www.nature.com

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · Sep 1

Daniel Roderer and his group revealed the first high-res structure of Fap2 from Fusobacterium nucleatum (cryo-EM/ET). Fap2 binds immune cells (TIGIT) and colorectal cancer cells (Gal-GalNAc), showing how Fusobacteria colonize tumors and escape the immune system.
www.nature.com/articles/s41...

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Max Ruwolt @mruwolt.bsky.social · Aug 20

Brace yourselves! Arif from the Fiedler lab discovered+characterized in collaboration with us & other groups within the @fmp-berlin.de a novel PTM: autocatalytic oligophosphorylation (up to 6 Phosphates 😲). Still mysterious in origin, function & regulation.

www.nature.com/articles/s41...

Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation - Nature Chemistry

Our understanding of how post-translational modification—protein phosphorylation—impacts the complexity of eukaryotic signalling pathways is continuously expanding. Now, protein oligophosphorylation h...

www.nature.com

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Sigrid Milles @millessigrid.bsky.social · Aug 21

I am happy to share our new article on dynamic Eps15 and Dab2 networks in endocytosis studied by #NMR, and forming #LLPS. Research was done at @fmp-berlin.de and at the Institut de Biologie Structurale (IBS).

www.nature.com/articles/s41...

Promiscuous and multivalent interactions between Eps15 and partner protein Dab2 generate a complex interaction network - Nature Communications

Eps15, a protein involved in endocytosis initiation, uses small folded EH domains to bind disordered partner proteins and its own disordered tail, thus forming a dynamic network via phase separation t...

www.nature.com

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · Aug 19

Great work by @broichhagenj.bsky.social at Leibniz-FMP, David Hodson at @rdm.ox.ac.uk and the whole team!

Radcliffe Department of Medicine @rdm.ox.ac.uk · Aug 19

A team of scientists has used fluorescent versions of next-generation diabetes & obesity drugs like Ozempic and Wegovy to reveal, for the first time, exactly which cells they target in the pancreas and brain.

#diabetes #obesity #Ozempic #Wegovy

@fmp-berlin.de

www.rdm.ox.ac.uk/news/scienti...

Scientists reveal how new diabetes and obesity drugs work

A team led by scientists at the University of Oxford and the Leibniz-Forschungsinstitut für Molekulare Pharmakologie in Berlin has used fluorescent versions of next-generation diabetes and obesity dru...

www.rdm.ox.ac.uk

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · Aug 14

⏰Join us for the NMR Symposium, Nov 26–27, 2025, celebrating our new 1.2 GHz NMR spectrometer. To present a poster, send your abstract to [email protected]. Registrations are open until September 15th!

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · Aug 13

Great cover art by @barthvanrossum.bsky.social for @jacs.acspublications.org: Influenza lifecycle showing M2’s roles, from activation in the low-pH endosome to viral uncoating, RNA release, and budding of new particles. View the article from the Lange lab here: pubs.acs.org/doi/10.1021/...

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · Aug 12

Thanks to Yanwei Su from @volkerhaucke-lab.bsky.social, we have a new scientific image of the month: When morphology gets romantic 🫶- this is a U2OS cell overexpressing Sec61b (ER), stained with LAMP1 (lysosome) and DAPI (nuclei), to test lysosome–ER membrane contact sites.

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Magnetic Resonance News @nmr900.bsky.social · Aug 11

PhD position on studying intrinsically disordered proteins by NMR and single molecule FRET, Dr. Sigrid Milles, The Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de Berlin, Germany leibniz-fmp.softgarden.io/job/58144047... #NMRjobs #NMRchat #NMR 🧲

PhD position on studying intrinsically disordered proteins by NMR and single molecule FRET (f/m/d) at Leibniz-Forschungsinstitut für Molekulare Pharmakologie

We're looking for: PhD position on studying intrinsically disordered proteins by NMR and single molecule FRET (f/m/d) (Part Time) • Berlin, Deutschland

leibniz-fmp.softgarden.io

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · Jul 4

Our scientific image of the month July comes from Kati Fischermanns, @broichhagenj.bsky.social lab and is titled: "96 wells celebrate diversity" 🌈 It was created by scaling up tunable photocontrol over cells.

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · Jul 3

With his exceptional work, Prof. Dr. Volker Haucke @volkerhaucke-lab.bsky.social has made it onto the #FallingWallsFoundation shortlist for the #ScienceBreakthrough of the Year 2025 in the #LifeSciences category. Congratulations!

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · Jul 2

The #LongNightoftheSciences at @fmp-berlin.de was a great success: Many visitors took a look behind the scenes during the lab tours and were inspired by research.

Thanks to everyone who came and see you around next year!

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Reposted by Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)

Leibniz-Gemeinschaft @leibniz-gemeinschaft.de · Jun 24

Kampf dem Kunststoff!
In der Forschung fallen Unmengen #Plastikmüll an. Lässt sich das ändern?
www.leibniz-magazin.de/alle-artikel...
#LeibnizMagazin #Müll #Nachhaltigkeit #Forschung @fmp-berlin.de

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · Jun 23

New in @jacs.acspublications.org:

New insights into the flu virus: The Lange lab used proton-detected solid-state NMR combined with the Sun lab's expertise in QM/MM+MD simulations to reveal how pH changes drive conformational shifts in the influenza A M2 channel.

pubs.acs.org/doi/10.1021/...

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Reposted by Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)

chrischmied.bsky.social @chrischmied.bsky.social · Jun 6

Wonderful to present my work leading a large European consortium around @fmp-berlin.de and @eu-openscreen.bsky.social at #ELMI2025. We produce large-scale #open-source high quality Cell Painting data for drug discovery 💊. First dataset published: doi.org/10.1016/j.is...

Stay tuned for more!

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · May 28

Get ready for this upcoming event:

Lecture series on Allostery in Drug Discovery 💊

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Get ready for this upcoming event, a lecture series on Allostery in Drug… | Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)

Get ready for this upcoming event, a lecture series on Allostery in Drug Discovery (ALLODD) - hosted by Prof. Dr. Marc Nazaré from Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and Dr....

www.linkedin.com

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · May 26

The lab of noalipstein.bsky.social introduced a new mouse line to label presynaptic terminals with chemical dyes, enabling imaging of fixed & live neurons at confocal & super-res. They synthesized & validated a cell-impermeable dye, BG-SiR-d12, improving image quality!

pubs.acs.org/doi/10.1021/...

Endogenous SNAP-Tagging of Munc13-1 for Monitoring Synapse Nanoarchitecture

Synaptic function is governed by highly regulated protein machineries, whose abundance and spatial localization change continually. Studies to determine dynamic changes in synaptic protein nanoarchit...

pubs.acs.org

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Reposted by Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)

chrischmied.bsky.social @chrischmied.bsky.social · May 14

Big step for open science! 🎉 Our @eu-openscreen.bsky.social consortium drops their first open Cell Painting dataset.

Wolff et al. 2025: doi.org/10.1016/j.is...

FAIR, high-quality & ready to power AI in drug discovery. 100K+ compounds coming in 2025!
#OpenData #CellPainting #DrugDiscovery

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · Apr 29

FMP-Director Volker Haucke in @tagesspiegel.de: Why we should not accept the US government's attack on science.

www.tagesspiegel.de/wissen/gleic... (article behind paywall)

Gleichschaltung in den USA : Solidarität mit US-Forschenden!

Die US-Regierung will Wissenschaft ideologisch kontrollieren. Das gefährdet die Grundprinzipien freier Forschung, die am besten in internationaler Kooperation gedeiht. Der Zellbiologe und Leibniz-Prei...

www.tagesspiegel.de

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Reposted by Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)

chrischmied.bsky.social @chrischmied.bsky.social · Apr 14

Join us for the CytoData Symposium and Hackathon: cytodata25.eu-openscreen.eu

Registration open now!

Symposium November 20–21, 2025
Hackathon November 17–19, 2025

@eu-openscreen.bsky.social @mdc-berlin.bsky.social @fmp-berlin.de @cytodata.bsky.social

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · Apr 3

Today was #GirlsDay 2025: An opportunity to show girls at @fmp-berlin.de what science has in store for them:

www.linkedin.com/feed/update/...

#girlsday #naturalsciences #lightandelectronmicroscopy #nmrspectroscopy… | Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)

Today was #GirlsDay 2025: An opportunity to show girls about professions or study subjects in which the proportion of women is below 40 percent, e.g. in the fields of #naturalsciences. 🔬👩‍🔬 12 school...

www.linkedin.com

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Reposted by Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)

Leibniz-Gemeinschaft @leibniz-gemeinschaft.de · Mar 31

🎉 Freie Wissenschaft. Starke Forschung. 30 Jahre Leibniz-Gemeinschaft. 🎉 Am 31.3.1995 wurden wir unter dem Namen „Wissenschaftsgemeinschaft Blaue Liste“ gegründet – ein Ergebnis der deutschen Wiedervereinigung & ein erfolgreicher Beitrag zum Zusammenwachsen der Wissenschaft in Ost und West. (1/4)

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) @fmp-berlin.de · Mar 25

Congratulations to @volkerhaucke-lab.bsky.social for receiving the Gottfried Wilhelm Leibniz Prize 2025 by @dfg.de
The award recognises Haucke's research on lipid signaling and synaptic transmission in the nervous system. Insights into his work can be found here:
www.youtube.com/watch?v=rl8m...

Volker Haucke - Gottfried Wilhelm Leibniz-Preisträger 2025 im Portrait

YouTube video by DFG bewegt

www.youtube.com

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