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γδ T cell Forum @forum-gd.bsky.social · 20h

IL-17-producing γδ T cells in the tumor microenvironment promote radioresistance in mice

#gdTcells @jci.org

JCI - IL-17-producing γδ T cells in the tumor microenvironment promote radioresistance in mice

www.jci.org

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γδ T cell Forum @forum-gd.bsky.social · 3d

A triple take on antigen receptor recognition of PE

#gdTcells

A triple take on antigen receptor recognition of PE

In this issue of Structure, Rashleigh et al. used cryoelectron microscopy to assess recognition of the model foreign antigen phycoerythrin (PE) by a γδTCR, an αβTCR, and an antibody. With potential re...

www.cell.com

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γδ T cell Forum @forum-gd.bsky.social · 3d

Antibody-like recognition of a γδ T cell receptor toward a foreign antigen

#gdTcells

Antibody-like recognition of a γδ T cell receptor toward a foreign antigen

Rashleigh et al. utilized phycoerythrin, a bacterial derived protein, to explore immune reactivity of B cells, αβ T cells, and γδ T cells. All lymphocytes directly recognized PE, while T cell recognit...

www.cell.com

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γδ T cell Forum @forum-gd.bsky.social · 12d

Microbial metabolic pathways guide response to immune checkpoint blockade therapy

#gdTcells

Microbial metabolic pathways guide response to immune checkpoint blockade therapy

Abstract. Studies have identified a link between specific microbiome-derived bacteria and immune checkpoint blockade (ICB) efficacy. However, these species lack consistency across studies and their im...

doi.org

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Reposted by γδ T cell Forum

Edelblum Lab @edelblumlab.bsky.social · Aug 28

👀 We're on the lookout for a talented immunologist to join us for a postdoc at Mount Sinai! If you are a recent PhD graduate, love spectral flow and want to join our γδ T cell crew, apply below! Livable wage + subsidized housing + Central Park. Help us spread the word! #gdTcells #Immunosky #GISky

Post Doctoral Fellow-MSH-20093-003 in New York, NY | Mount Sinai Health Systems

Mount Sinai is hiring a Post Doctoral Fellow-MSH-20093-003 in New York, NY. Review all of the job details and apply today!

careers.mountsinai.org

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Monika Wolkers @monikawolkers.bsky.social · Sep 3

our study on #gdTcells in pediatric neuroblastoma is out! In contrast to adult tumors, it is the gdTcells that not only expand, but that are the most tumor reactive #TILs.

#immunology #tumorimmunology

funded by KIKA, Sanquin and supported by Oncode

www.life-science-alliance.org/content/8/11...

γδ T cells are the prime antitumoral T cells in pediatric neuroblastoma

High-risk pediatric neuroblastoma patients have a dismal survival rate despite intensive treatment regimens. New treatment options are thus required. Even though HLA expression in neuroblastoma is low...

www.life-science-alliance.org

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Seth Coffelt @coffeltlab.bsky.social · Sep 9

check out our new commentary on 2 recently published papers about #gdTcells in breast cancer
www.sciencedirect.com/science/arti...

γδT cells and breast cancer: wicked allies

Metastatic disease and therapy resistance pose significant challenges in the treatment of breast cancer. Recent studies by Rozalén et al. and Petroni …

www.sciencedirect.com

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Eberl Lab 👨🏻‍🔬👩🏽‍💻🔬🧫 @eberllab.bsky.social · 15d

"Microbe-responsive human γδ T cells: The peculiar case of Staphylococcus aureus"

To Armin and Martin. 🕯️

#gdTcells

<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library

Human Vγ9/Vδ2 T cells display a unique responsiveness towards microbial organisms producing the metabolite HMB-PP. However, Staphylococcus aureus does not possess HMB-PP but can induce activation, cy...

onlinelibrary.wiley.com

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Neil McCarthy @neilemccarthy.bsky.social · 17d

📚 NEW #gdT-cell PAPER from our team @QMUL.bsky.social! 🥳 'Bacterial suppression of intestinal fungi via activation of human gut γδ T-cells' out now on @biorxiv-immuno
www.biorxiv.org/content/10.1... Here's my first attempt at a 'Bluetorial'... 🧵 1/10 #gastrosky #IBDsky

Bacterial suppression of intestinal fungi via activation of human gut γδ T-cells

Gut symbionts condition mucosal immunity to resist infection by enteropathogens, but the specific microbes and mechanisms involved differ significantly between host species. In higher primates, bacter...

www.biorxiv.org

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γδ T cell Forum @forum-gd.bsky.social · 20d

If you missed today's seminars by Drs. Inacio and Gonzalez, please see the recorded sessions here:

nyulangone.zoom.us/rec/share/Ai...
Passcode: GDTcellclub_Sept2025

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γδ T cell Forum @forum-gd.bsky.social · 20d

Our next speaker is Dr Octavio Gonzalez, sharing his work on the impact of aging on gingival gd T cells.

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γδ T cell Forum @forum-gd.bsky.social · 20d

Our second speaker, Dr. Octavio Duque will talk about the effect of aging on gingival gdTs. Please join us! #GDTcells

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γδ T cell Forum @forum-gd.bsky.social · 20d

Join us now to hear from Dr Daniel Inácio about the molecular control of gd T cell subset differentiation and effector function.

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γδ T cell Forum @forum-gd.bsky.social · 20d

Starting up with Dr. Daniel P. Inacio from Univ. of Lisbon about effector functions of #GDTcells.. join us!

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Payal Yokota @payalyokota.bsky.social · 21d

Please join us for the upcoming September #GDTcellclub Virtual talks by Drs. Daniel P. Inacio and Octavio A. Gonzalez on Sept 18 at 12pm NY/5pm Lisbon

Bookmark for up-to-date announcements 👇
payalyokota.com/gamma-delta-...

Zoom: nyulangone.zoom.us/j/9589051706...

@forum-gd.bsky.social

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γδ T cell Forum @forum-gd.bsky.social · 21d

Join us tomorrow for our next #GDTcellclub webinar, where we are delighted to host Drs Octavio Gonzalez and Daniel Inácio.

Date: September 18, 2025
Time: 12pm (New York) | 5pm (London, UK)

nyulangone.zoom.us/j/9589051706...

*Talks will be recorded* for those who are unable to attend live.

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γδ T cell Forum @forum-gd.bsky.social · 22d

TLR2 supports γδ T cell IL-17A response to ocular surface commensals by metabolic reprogramming

#gdTcells @jem.org

TLR2 supports γδ T cell IL-17A response to ocular surface commensals by metabolic reprogramming

Ocular commensal C. mast induces IL-17 responses from Vγ6 T cells, helping to maintain mucosal barrier function of the conjunctiva. Mechanistically, Vγ6 T

rupress.org

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γδ T cell Forum @forum-gd.bsky.social · 29d

Cytotoxic CX3CR1+ Vδ1 T cells clonally expand in an interplay of CMV, microbiota, and HIV-1 persistence in people on antiretroviral therapy

#gdTcells

Cytotoxic CX3CR1+ Vδ1 T cells clonally expand in an interplay of CMV, microbiota, and HIV-1 persistence in people on antiretroviral therapy

Author summary Vδ1 T cells are key immune cells, particularly in the intestinal mucosa, which is a major site of HIV-1 persistence during antiretroviral therapy. Disruption of the gut microenvironment...

journals.plos.org

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γδ T cell Forum @forum-gd.bsky.social · 29d

Metabolic control of innate-like T cells

#gdTcells @natrevimmunol.nature.com

Metabolic control of innate-like T cells - Nature Reviews Immunology

Functional and metabolic properties of innate-like T cells — namely, iNKT cells, MAIT cells and some γδ T cells — differ from those of conventional T cells. This Review describes how metabolic pathway...

www.nature.com

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γδ T cell Forum @forum-gd.bsky.social · Aug 30

Phenoscaping Reveals Multimodal γδ T Cell Cytotoxicity as a Strategy to Overcome Cancer Cell-Mediated Immunomodulation Open Access

#gdTcells @aacrjournals.bsky.social

Phenoscaping Reveals Multimodal γδ T Cell Cytotoxicity as a Strategy to Overcome Cancer Cell-Mediated Immunomodulation

Abstract. γδ T cells can kill cancer cells via antibody-independent cytotoxicity (AIC) and antibody-dependent cellular cytotoxicity (ADCC). A better understanding of how these cytotoxic mechanisms are...

aacrjournals.org

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γδ T cell Forum @forum-gd.bsky.social · Aug 29

MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines

#gdTcells

MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines

Memory T cells drive early reactogenic responses to mRNA boosters via MAIT/innate-like T cells, which are tempered by dosing interval.

www.science.org

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γδ T cell Forum @forum-gd.bsky.social · Aug 26

Don't miss the upcoming #Globalimmunotalk by Prof Adrian Hayday on August 27. I am sure it will be an absolute treat!

Talk Title: Lymphoid stress-surveillance, normality sensing, and integrated immunology.

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γδ T cell Forum @forum-gd.bsky.social · Aug 21

Thank you again for joining us for the August 21, #GDTcellclub seminars by Drs. Amit Sharma and Xiaoyan Xu.

Here's a recording from today's talks:
nyulangone.zoom.us/rec/share/Wq...

Passcode: #GDTcellclubAug2125

Please feel free to post your questions by replying to this thread!

γδ T cell Forum @forum-gd.bsky.social · Aug 21

Starting in less than 30min, join us for two fantastic talks by Drs. Amit Sharma and Xiaoyan Xu today for our August #GDTcellclub seminar.

We can't wait to *see* you!
zoom information below

γδ T cell Forum @forum-gd.bsky.social · Aug 16

We are excited to host Drs. Amit Sharma and Xiaoyan Xu for our upcoming #GDTcellclub virtual talks.

Date: August 21, 2025
Time: 12pm (New York) | 5pm (London, UK)

nyulangone.zoom.us/j/9589051706...

*Talks will be recorded* for those who are unable to attend live.

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γδ T cell Forum @forum-gd.bsky.social · Aug 21

Next up today, we have Dr. Amit Sharma presenting his work on gd T cells in aging and fibrosis.

γδ T cell Forum @forum-gd.bsky.social · Aug 21

Our first speaker today is Dr. Xiaoyan Xu talking about the ocular gd T cell response to Corynebacterium mastitidis.

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