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Franck Polleux

@franckp.bsky.social

2K followers 1.9K following 59 posts

Neuroscientist and cell biologist. Investigator of the Zuckerman Mind Brain Behavior Institute (ZMBBI) in New York

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Franck Polleux @franckp.bsky.social · Dec 18

Delighted to highlight our new paper in
@natureportfolio.bsky.social entitled 'Synaptic basis of feature selectivity in hippocampal neurons' (thread below 👇): www.nature.com/articles/s41...

Synaptic basis of feature selectivity in hippocampal neurons - Nature

A temporally asymmetric synaptic plasticity kernel results from bidirectional modifications of synaptic weights around the induction of a place field.

www.nature.com

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Reposted by Franck Polleux

🦋Dr. Natalia🕊🌻🪬 @solnatamd.medsky.social · 1d

Six surgeons general...are coming late to the fight.

No paywall: archive.ph/cW4yJ

Opinion | Six surgeons general: It’s our duty to warn the nation about RFK Jr.

We took an oath to declare dangers when we found them. We’re doing that again today.

www.washingtonpost.com

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Khashoggi's Ghost @urocklive1.bsky.social · 5d

The intellectual purge continues.

Last month Marrazzo said she had been silenced when she and her colleagues pushed back against NIH officials who questioned the importance of childhood flu vaccines and canceled long-running clinical trials.

www.cbsnews.com/news/rfk-jr-...

RFK Jr. fires NIH vaccine whistleblower Dr. Jeanne Marrazzo

RFK Jr. fired infectious disease specialist Dr. Jeanne Marrazzo, who told CBS News she was put on leave after questioning actions taken by Trump appointees.

www.cbsnews.com

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Franck Polleux @franckp.bsky.social · 8d

😔

Jeremy Berg @jeremymberg.bsky.social · 8d

Compelling and quite disturbing...

LorennaCleary.bsky.social @lorennacleary.bsky.social · 9d

Land of the free. Home of the brave.

Reposted by Franck Polleux

Yonah Freemark @yonahfreemark.com · 9d

Paris celebrated the opening of its 300th “school street”: landscaped & pedestrianized or semi-pedestrianized blocks situated in front of schools. Most have been completed since 2020.

Paris passe le cap des 300 rues piétonnes près des écoles pour être « plus accueillante aux enfants »

La municipalité, qui a organisé samedi une fête dédiée, tire un bilan positif de ces espaces piétonnisés aux abords des établissements scola

leparisien.fr

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Brad Lander @bradlander.bsky.social · 13d

I was back at 26 Federal Plaza today, where an ICE agent violently threw this bereft woman to the ground in front of her kids. She had not touched him. She did not pose any threat. She had to be taken to the hospital. (🎥: Elias Eliahu)

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Franck Polleux @franckp.bsky.social · 17d

Please repost and share on other platforms!

Franck Polleux @franckp.bsky.social · 17d

Luke Hammond also made a great video tutorial about how to use RESPAN available on Youtube:
www.youtube.com/watch?v=Q6zu...

Automated Analysis of Dendritic Spines using Deep Learning with RESPAN

YouTube video by Cellular Imaging

www.youtube.com

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Franck Polleux @franckp.bsky.social · 17d

This interface is easy to use, robust and outperforms human observer-based mapping of dendritic spines. We want as many lab as possible to try this new open-access approach! Available for free on Github:
github.com/lahammond/re...

GitHub - lahammond/RESPAN: Robust, accurate, and unbiased quantification of neurons and dendritic spines.

Robust, accurate, and unbiased quantification of neurons and dendritic spines. - lahammond/RESPAN

github.com

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Franck Polleux @franckp.bsky.social · 17d

Excited to highlight a new paper from my graduate student Sergio Bernal Garcia who, together withLuke Hammond, developed RESPAN, a new deep-learning pipeline automating the segmentation of neuronal morphology and dendritic spines from fluorescent microscopy images:
www.cell.com/cell-reports...

A deep learning pipeline for accurate and automated restoration, segmentation, and quantification of dendritic spines

Garcia et al. present RESPAN, a pipeline that enables automated dendritic spine analysis through seamless integration of deep learning image restoration and segmentation capabilities with comprehensiv...

www.cell.com

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Julia Schaeffer | Axon regulation and regrowth lab @axonreg2lab.bsky.social · 27d

✨ Post-doc opportunity in axon biology, funded by #ATIP-Avenir!

👀 We are looking for an enthusiastic post-doc to join our team at @ibdm.bsky.social to explore translation dynamics in axon regrowth, using live imaging approaches.

Apply at: emploi.cnrs.fr/Offres/CDD/U...

Thank you for sharing! 👋 🙏

Portail Emploi CNRS - Offre d'emploi - Post-doctoral researcher in axon biology (M/F)

emploi.cnrs.fr

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Carl T. Bergstrom @carlbergstrom.com · Sep 6

Simpering cowards one and all.

This is almost unbearable to watch.

Ketan Joshi @ketanjoshi.co · Sep 6

Incredible clip of tech CEOs fawning over Donald Trump. Someone store this clip in the underground archive vault

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Franck Polleux @franckp.bsky.social · Sep 5

fascinating results👇

Maria Antonietta Tosches @matosches.bsky.social · Aug 25

Excited to share our latest work on brain evolution, where we dive into the evolution of Cajal-Retzius cells! If you are interested in cell type evolution and cerebral cortex evo-devo, please read on… www.biorxiv.org/content/10.1... 🧵 1/7

Evolution of Cajal-Retzius Cells in Vertebrates from an Ancient Class of Tp73+ Neurons

In the developing cerebral cortex, Cajal Retzius (CR) cells are early-born neurons that orchestrate the development of mammalian-specific cortical features. However, this cell type has not been conclu...

www.biorxiv.org

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Jenny Frecklington-Jones #IStandWithWatermelon🍉🍉 @joneshowdareyou.bsky.social · Sep 2

I enjoyed this. And what an infectious laugh. ❤️

"Reporter left speechless after witnessing Japan's new $70 million Maglev train in action at 310 mph"

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Carl T. Bergstrom @carlbergstrom.com · Feb 4

Modern-Day Oracles or Bullshit Machines?

Jevin West (@jevinwest.bsky.social) and I have spent the last eight months developing the course on large language models (LLMs) that we think every college freshman needs to take.

thebullshitmachines.com

INTRODUCTION

thebullshitmachines.com

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Carl T. Bergstrom @carlbergstrom.com · Aug 23

In 25 years, every business school in the country will be doing case studies about how a long defunct company known as “Google” once had an unbeatable lock on online information retrieval and then started doing shit like this.

Google
Sign in
is dunkin cereal milk gluten fr

Al Overview

+1
No, Dunkin' Cereal Milk is not gluten-free because it contains milk, which is a common allergen, and as a result, it is not suitable for those with celiac disease or gluten intolerance.
However, coffee drinks, dairy milk, and non-dairy milks like oat, almond, and coconut milk are naturally gluten-free at Dunkin'.

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Franck Polleux @franckp.bsky.social · Jul 8

Watch this video about the new Vera Rubin telescope. Truly remarkable scientific and engineering achievement, so much to learn about our universe! I In these troubled times, it's so refreshing and stimulating to realize how transformative science and human ingenuity can be 👇

Keith Smith @drkeithsmith.bsky.social · Jul 7

What is the Rubin Observatory and why are astronomers so excited about it? My colleague @danclery.bsky.social has been to the telescope and spoken to some of the scientists who will use it. This video is well worth 10mins of your time. 🔭🧪
m.youtube.com/watch?v=2C77...

A new eye on the universe is about to open

YouTube video by Science Magazine

m.youtube.com

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Don Moynihan @donmoyn.bsky.social · Jul 4

New, from me:
The Times published a piece accusing a man born in Africa as claiming to be African-American in a failed college admission.

They viewed this story to be newsworthy enough to grant anonymity to a eugenicist working with hacked personal data.
donmoynihan.substack.com/p/whos-afrai...

Who's Afraid of Zohran Mamdani?

And what it means to be an immigrant on July 4th

donmoynihan.substack.com

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David Roberts @volts.wtf · Jul 2

Elon Musk casually, and illegally, dismantled USAID. According to a new study in the Lancet, that action will lead to *14 million* premature deaths between 2025 and 2030.

Again: Elon Musk is directly responsible for 14 million coming deaths. 4.5 million will be children.

Evaluating the impact of two decades of USAID interventions and projecting the effects of defunding on mortality up to 2030: a retrospective impact evaluation and forecasting analysis

USAID funding has significantly contributed to the reduction in adult and child mortality across low-income and middle-income countries over the past two decades. Our estimates show that, unless the a...

www.thelancet.com

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Dr. Tom Frieden @drtomfrieden.bsky.social · Jun 10

Dissolving ACIP is an absolute mistake. We need accurate information—not fringe theories—guiding government recommendations on which vaccines to give which people.

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Senator Patty Murray @murray.senate.gov · Jun 10

My message to Trump’s NIH Director? No one in America wants us to do LESS cancer research.

No one is asking Trump to make it harder to cure Alzheimer's disease.

Yet Trump is cutting all of this NOW and demanding an $18 BILLION cut to NIH next year. Not on my watch.

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David Rothschild @davmicrot.bsky.social · Jun 10

Trump sends 5,000 military to invade & occupy LA, and NYT headline is literal false-equivalency he-said-she-said.

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Elizabeth Warren @warren.senate.gov · Jun 9

RFK Jr.‘s extreme anti-vax views — and his related conflicts of interest — were a huge problem during his confirmation process.

So he promised not to change the vaccine advisory panel.

Today, he fired every single expert on that panel. It's a public health disaster.

RFK Jr. ousts entire CDC vaccine advisory committee

Health Secretary Robert F. Kennedy Jr. has removed every member of a scientific committee that advises the Centers for Disease Control and Prevention on how to use vaccines.

apnews.com

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WHO @who.int · Jun 10

Vaccines are rigorously tested, they are effective, and they save lives. More than 150 million lives have been saved in the past 50 years thanks to vaccines!

But you may be worried about what's in them?
So, let’s break it down ⬇

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Joris de Wit @synapse-lab.bsky.social · Apr 8

Postdoc opportunity in the heart of Europe! Check out the flyer below.
Join our team on an international project with Anthony Holtmaat exploring synaptic plasticity and specificity in cortical and thalamocortical circuits.

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Joris de Wit @synapse-lab.bsky.social · May 20

Glad to see our new paper finally out! We show how the GPR158 receptor controls synapse maturation and function by silencing an intrinsic inhibitory mechanism.
authors.elsevier.com/a/1l7HS5Sx5g...
Work from Ben Verpoort and colleagues, with special thanks to our collaborators.

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