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Reposted by David L. Stern

Sean Eddy @cryptogenomicon.bsky.social · 11h

In the history of authoritarian regimes promoting pseudoscience for ideological reasons, one that I just learned about: "World Ice Theory" and the Nazis.

www.laphamsquarterly.org/roundtable/s...

A Song of Ice and Fire | Eric Kurlander

World Ice Theory and the supernatural imaginary of the Third Reich.

www.laphamsquarterly.org

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Reposted by David L. Stern

Richard Sever @richardsever.bsky.social · 18h

Very sad to learn of the death of Sir John Gurdon. He made a huge contribution to developmental biology & should be an inspiration to anyone whose potential is dismissed in school. It was a pleasure to work with him when he was Chair of the COB Board. www2.mrc-lmb.cam.ac.uk/john-gurdon-...

John Gurdon (1933 – 2025) - MRC Laboratory of Molecular Biology

Renowned developmental biologist John Gurdon, former Group Leader and Head of the LMB’s Cell Biology Division, has died aged 92.

www2.mrc-lmb.cam.ac.uk

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Reposted by David L. Stern

Fillip Port @crisprflydesign.bsky.social · 4d

High levels of Cas9 are toxic in sensory neurons. Reducing Cas9 levels with uORFs avoids toxicity and is compatible with efficient editing. From @thompsonpeerlab.bsky.social. Fly lines @vdrc-flies.bsky.social

#CRISPR #Drosophila

www.biorxiv.org/content/10.1...

Figure from the preprint showing sensory neuron morphology with different levels of Cas9 expression.

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Reposted by David L. Stern

Andrea Junker @strandjunker.com · 4d

“Terrible things are happening outside. Poor helpless people are being dragged out of their homes. Families are torn apart. Men, women, and children are separated. Children come home from school to find that their parents have disappeared.”

Diary of Anne Frank
January 13, 1943

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Reposted by David L. Stern

FlyBase @flybase.bsky.social · 5d

There's an update on the state of FlyBase on the FlyBase.org front page. You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase...
We express enormous gratitude to the people, labs, groups, and foundations who have already helped us.
#FlyBase #Drosophila

FlyBase Update – October 2025
The termination of the NIH/NHGRI FlyBase grant has placed the long-term sustainability of FlyBase at risk. However, thanks to the generous support of several key individuals and institutions, we are pleased to announce that FlyBase will remain operational through the coming year. We extend our deepest gratitude to Yukiko Yamashita, Cassandra Extavour, Hugo Bellen, Thom Kaufman, the Genetics Society of America / Drosophila Board, the Bloomington Drosophila Stock Center, an anonymous donor and the Wellcome Trust. We are especially thankful for a generous gift from Seemay Chou, Jed McCaleb, and The Navigation Fund. We also greatly appreciate the continued support from the broader Drosophila community – your donations and service fees have been vital in helping us stay afloat. Special thanks also go to Jessica Manning for her tireless administrative work at Harvard, to Ruth Lehmann, Hugo Bellen, and Paul Sternberg for advice and efforts, and to the Board of the European Drosophila Society for all their efforts. Sadly, we must also share that several long-standing FlyBase team members have recently moved on. We are immensely grateful to Susan Russo-Gelbart, Lynn Crosby, Gil dos Santos, Kris Broll, Victoria Jenkins, and TyAnna Lovato for their many years of dedicated service and contributions to FlyBase. Looking ahead, ensuring FlyBase’s sustainability beyond the next year – and successfully integrating with the Alliance – will require new funding sources. We kindly ask for your continued support:
• European labs: Please consider contributing to the Cambridge, U.K. FlyBase group
• U.S. and other non-European labs: Please consider contributing to the U.S. FlyBase groups
• Both U.K. and U.S. FlyBase are working diligently to establish an invoicing system. We appreciate your continued patience.
For more information on how to support us, please visit: Contribute to FlyBase wiki page https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase

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Reposted by David L. Stern

Sweta Agrawal @hokuba.bsky.social · 7d

The Agrawal lab is moving! This January we will be setting up shop at #UBC in Vancouver, in the department of #Zoology! We are actively recruiting at all levels, especially masters and PhD students. These position are #funded! Please send anyone interested my way!

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David L. Stern @gallseeker.bsky.social · 6d

Haha. Part of the lab will be working to shorten their lives. But, yeah!

David L. Stern @gallseeker.bsky.social · 8d

Thanks Arnaud. Sorry to be leaving the DMV, but onward, upward, and westward.

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David L. Stern @gallseeker.bsky.social · 8d

Thanks Fillip!

David L. Stern @gallseeker.bsky.social · 8d

Thanks James. Much closer to Utah...

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David L. Stern @gallseeker.bsky.social · 8d

Thanks Alicia! Very exciting opportunity!

Reposted by David L. Stern

Stowers Institute @stowersinstitute.bsky.social · 8d

(Part 1) Hear from @hhmi_news Investigator David Stern about his research program and what he's uncovering in the lab.

Stern will join the Institute in February 2026, bringing his lab and HHMI appointment to Kansas City. @hhmi.org

Read more: bit.ly/4np96Fb

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Reposted by David L. Stern

Stowers Institute @stowersinstitute.bsky.social · 8d

(Part 2)

“From my first visit, I was struck by the energy and excitement...It feels like being a graduate student again, chasing curiosity wherever it leads."

@hhmi.org Investigator David Stern will join the Stowers Institute in Feb. 2026 from @hhmijanelia.bsky.social.

Read more: bit.ly/4np96Fb

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David L. Stern @gallseeker.bsky.social · 8d

It's official! We are moving to Stowers!
Very exciting opportunity to expand our studies of insect-plant interactions. We have many opportunities available in biochemistry, development, behavior, genetics, evolution, genomics, AI, and even pest control. Interested in any of these things? Reach out!

Stowers Institute @stowersinstitute.bsky.social · 8d

NEWS🎉 We’re excited to announce @hhmijanelia.bsky.social Investigator David Stern will join the Institute from Janelia Research Campus. His lab studies how aphids transform plants at the genetic level, uncovering secrets of #evolution & new strategies for pest control. @hhmi.org bit.ly/4np96Fb

Stowers Institute recruits renowned developmental and evolutionary…

David Stern, Ph.D., brings groundbreaking research on insect–plant interactions for next-generation pest control to the Institute.

bit.ly

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Reposted by David L. Stern

Rebecca R Helm @rebeccarhelm.bsky.social · 14d

I get that the news cycle is packed right now, but I just heard from a colleague at the Smithsonian that this is fully a GIANT SQUID BEING EATEN BY A SPERM WHALE and it’s possibly the first ever confirmed video according to a friend at NOAA

10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)

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Reposted by David L. Stern

Daniel Kronauer @danielkronauer.bsky.social · 19d

The final version of our paper on how ants and possibly other insects use a crazy mechanism involving extensive transcriptional interference to regulate odorant receptor expression is now open access in my favorite journal, @currentbiology.bsky.social

authors.elsevier.com/sd/article/S...

ScienceDirect.com | Science, health and medical journals, full text articles and books.

authors.elsevier.com

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Reposted by David L. Stern

Timothy Bredy @twbredy.bsky.social · 19d

How do neurons deal with fitting large regulatory proteins into small spaces to control plasticity and memory? By generating micropeptides via local translation of circRNAs, of course! Here’s to shedding new light on the ‘dark’ proteome in the brain.

www.biorxiv.org/cgi/content/...

Local translation of circular RNAs is required for synaptic activity and memory

Circular RNAs (circRNAs) are enriched in synapses and implicated in cognitive processes, and recent studies have shown that circRNAs can encode micropeptides, which suggests that there may be novel sy...

www.biorxiv.org

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Reposted by David L. Stern

Nature Methods @natmethods.nature.com · 20d

GPU-accelerated MMseqs2 offers tremendous speedup for homology retrieval, protein structure prediction with ColabFold, and protein structure search with Foldseek. @martinsteinegger.bsky.social @milot.bsky.social @machine.learning.bio

www.nature.com/articles/s41...

GPU-accelerated homology search with MMseqs2 - Nature Methods

Graphics processing unit-accelerated MMseqs2 offers tremendous speedups for homology retrieval from metagenomic databases, query-centered multiple sequence alignment generation for structure predictio...

www.nature.com

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Reposted by David L. Stern

Stowers Institute @stowersinstitute.bsky.social · 20d

#PhD applications are NOW OPEN! Hear from an alum⬇️

Stowers Grad School @stowersgrad.bsky.social · 20d

“Support. Connection. Coffee.” ☕ Three words Melvin Noe Gonzalez uses to describe their Stowers #PhD experience. Independently fully funded, hands-on, and collaborative, join a community that fuels curiosity.

Apply now: bit.ly/44VM6DI

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Reposted by David L. Stern

Audrey Truschke @audreytruschke.bsky.social · May 22

Recalling this bit of history — When the shooting of a German diplomat in 1938 was used by the Nazis as a pretext for Kristallnacht.

Individual violence doesn’t justify state bigotry and oppression, ever.

www.history.com/articles/kri...

Kristallnacht Started When This Diplomat Was Murdered in Cold Blood | HISTORY

Ernst vom Rath’s murder triggered a two-day pogrom against German Jews.

www.history.com

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Reposted by David L. Stern

Chris Jiggins @chrisjiggins.bsky.social · 28d

Looking for a PhD? I am advertising two industry sponsored PhD projects. One on black soldier fly genetics with #betabugs and another on searching insect biodiversity for novel enzymes #Syngenta. Get in touch if you are interested!! bbsrcdtp.lifesci.cam.ac.uk/available-ic...

Available iCASE projects | Cambridge Biosciences DTP PhD Programme

iCASE projects for academic year 2026-2027 line_divider.png Project: Understanding cellulose digestion by cryo-EM structure of cellulose microfibril-enzyme complexes Project reference: ICS-BIO-PD26 S...

bbsrcdtp.lifesci.cam.ac.uk

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Reposted by David L. Stern

Dr. Aaron Thierry @thierryaaron.bsky.social · 28d

As the world rapidly heads into #climate #overshoot I've noticed a disturbing pattern in journal articles recently.

I'll summarize it quickly in this thread 🧵

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Reposted by David L. Stern

Heng Li @lh3lh3.bsky.social · 29d

minimap2.com is potentially a phishing site. Please don't use anything from that website.
github.com/lh3/minimap2...

Phishing site : minimap2.com · Issue #1316 · lh3/minimap2

Not sure how to label this one, but I have come across a website minimap2.com which appears to be AI generated but is serving it's own copy of the Github repository. If you search the address or em...

github.com

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Reposted by David L. Stern

Kevin Mitchell @wiringthebrain.bsky.social · Sep 7

We're going to see a lot of bullshit in the coming days and weeks about "causes of autism", and most will be based on flawed, over-interpreted observational studies (1/n)

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David L. Stern @gallseeker.bsky.social · Sep 6

Just imagine, to these ants, giving birth to individuals of only one species is weird.

Nature @nature.com · Sep 5

The discovery of an unusual reproductive system for one ant species solves a long-standing puzzle

go.nature.com/47mxGkM

Ant queens produce sons of two distinct species

The discovery of an unusual reproductive system for one ant species solves a long-standing puzzle about a missing population of another ant species.

go.nature.com

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