Doran Goldman
@goldmandoran.bsky.social
940 followers 740 following 13 posts
UW-Madison Microbiology PhD student in the @molabuw.bsky.social, studying phage infection in microbial communities. Microbial ecology & evolution. Fan of birds, books, bacteriophages, and Beckett.
Posts Media Videos Starter Packs
Pinned
goldmandoran.bsky.social
I’m thrilled to share my first ever publication, now published in PNAS! www.pnas.org/doi/10.1073/...

With mentorship from the amazing @ksxue.bsky.social, I looked at how the outcomes of species introductions to microbial communities are influenced by the number of introduced microbes.
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
goldmandoran.bsky.social
Deadline for this is tonight! Now is the time to sign up!!
snapcoalition.bsky.social
SCIENTISTS.

Participate in a congressional home office visit this August to advocate for science funding!

SNAP will set up the meeting, train you, & support your message. Sign up by Aug 1 to join: forms.gle/sqcMeZn5YTsW...

#DefendResearch #ScienceAdvocacy #SciencePolicy
SNAP Congressional District Visit Day Sign Up Form
SNAP (Science Network for Advocacy and Policy) is a grassroots, primarily graduate student-led organization working to build the next generation of science policy leaders. We’re organizing in-district...
forms.gle
Reposted by Doran Goldman
ksxue.bsky.social
The Xue lab at UC Irvine is looking for a staff scientist to support our work investigating how microbes interact and evolve in the gut microbiome! Open to a wide range of previous experience levels, see ad for more.
recruit.ap.uci.edu/JPF09601
Junior, Assistant, or Associate Specialist – Xue Lab
University of California, Irvine is hiring. Apply now!
recruit.ap.uci.edu
Reposted by Doran Goldman
Reposted by Doran Goldman
ksxue.bsky.social
Want to write to your community about the importance of science funding?

Join me on zoom this Friday at 12pm ET / 9am PT to learn to write an op-ed as part of the #McClintockLetters initiative!

Sign up to write a letter and register for the workshop here:
blogs.cornell.edu/asap/events-...
A flyer with the heading McClintock Letter-Writing Workshop. Details are Friday, June 6th, 12pm ET and 9am PT, virtual.
Reposted by Doran Goldman
ksxue.bsky.social
Scientists, reach out to your local communities about the importance of funding science! Write an op-ed to your local newspaper as part of the #McClintockLetters.

Please spread the word and sign up! DM me if you're interested and need help getting started. I'm trained as a writer and happy to help.
isakoditomassi.bsky.social
Yes! Scientists, let's share our work with the public. Write an LTE/op-ed/ or guest column in a LOCAL HOMETOWN PAPER, published June 16! #McClintockLetters #SciComm

Share how we serve the public with fed dollars, & insights into fed funded research. Signup + more info: tinyurl.com/McClintockLetters
goldmandoran.bsky.social
This is a fantastic initiative and I would highly encourage folks to participate!
isakoditomassi.bsky.social
Yes! Scientists, let's share our work with the public. Write an LTE/op-ed/ or guest column in a LOCAL HOMETOWN PAPER, published June 16! #McClintockLetters #SciComm

Share how we serve the public with fed dollars, & insights into fed funded research. Signup + more info: tinyurl.com/McClintockLetters
Reposted by Doran Goldman
ashyeneng.bsky.social
I wrote/interviewed folx shortly after everything started to crumble in Jan, but I was re-reminded that communities prevail. There are amazing people doing beautiful things to improve our communities, and I’m excited to highlight their work. berkeleysciencereview.com/article/2025...
Reposted by Doran Goldman
angeljhv.bsky.social
The 2nd Hablemos de Ciencia Symposium was a success! This event was started last year to create a venue for UW-Madison researchers to communicate science in Spanish. Science is done for and by speakers of different languages. The language(s) that we use to communicate science should reflect that!
goldmandoran.bsky.social
Really honored to read this thoughtful perspective on our paper, thanks so much to @contaminatedsci.bsky.social!
contaminatedsci.bsky.social
Our commentary on the elegant in vitro microbiome coalescence experiments from @goldmandoran.bsky.social @ksxue.bsky.social et al is out.

It was a pleasure to write about one of my favorite microbiome papers of the last few years.

www.pnas.org/doi/10.1073/...
Mixing microbiomes in vitro reveals rules of community assembly | PNAS
Mixing microbiomes in vitro reveals rules of community assembly
www.pnas.org
Reposted by Doran Goldman
maikemorrison.bsky.social
1/ Hey y'all, I'm excited to share my latest paper, which is out now in PNAS! We introduce FAVA, a statistical framework to measure compositional variability across microbiome samples. If you want to measure variability across a stacked bar plot, FAVA is for you! Paper: doi.org/10.1073/pnas...
5 relative abundance plots arranged to have increasing compositional variability (variability across relative abundance samples, here vertical bars)
goldmandoran.bsky.social
Huge thank you to my mentors @ksxue.bsky.social, KC Huang, David Relman, @benjaminhgood.bsky.social, @petrovadmitri.bsky.social, and everyone else involved in the work for their valuable feedback and suggestions throughout, and I’m super excited to finally have this out in the world!
goldmandoran.bsky.social
Overall, our findings demonstrate that initial conditions can have a lasting impact on the outcomes of species introductions, and that these impacts are especially pronounced in diverse communities.
A graphical abstract titled “Introduced species show stronger, longer-lasting dose dependence when they have high niche overlap with resident species.” Below the title are two rows of images. In the top row from left to right are a culture flask labeled “low community diversity”, a Venn diagram labeled “low niche overlap” with two slightly overlapping circles labeled “species 1” and “species 2”, and a plot titled “weak dose dependence” that shows inoculation dose on the x-axis and relative abundance on the y-axis with two flat lines corresponding to the two species. In the bottom row from left to right are a flask labeled “high community diversity”, a Venn diagram titled “high niche overlap” with strongly overlapping circles, and a plot titled “strong dose dependence” with two relative abundance lines that slope strongly in opposite directions.
goldmandoran.bsky.social
Using a consumer-resource model and metabolomics, we identified niche overlap between introduced and resident species as a strong predictor of the importance of initial dose.
A schematic with two rows of images. In the top row on the left are a set of colored bars of different sizes representing the relative resource niche sizes of two species. The bars are mostly non-overlapping and are labeled “low niche overlap, fast equilibration.” On the right is a plot that shows mixture ratio on the x-axis and relative abundance on the y-axis, with a flat line showing a lack of dose dependence for a single species. In the bottom row from left to right are a set of colored bars with greater overlap labeled “high niche overlap, slow equilibration” and a plot showing a sloped line representing stronger dose dependence for a single species.
goldmandoran.bsky.social
The answer? It’s complicated, of course, and depends on the identity of the introduced microbes and which species are already present. Across a set of mixtures of gut microbial communities, we observed a range of species colonization behaviors from dose independence to strong dose dependence.
Three plots with mixture ratio on the x-axis and relative abundance on the y-axis. Each plot shows the relative abundance of a single species at passage 0 and 5 after community mixtures. The plot on the left is labeled “strong colonizer” and shows a species whose relative abundance at passage 5 is flat across mixture ratios and above its passage 0 abundance. The plot in the middle is labeled “weak colonizer” and shows a species whose relative abundance is at passage 5 is flat across mixture ratios and lower than its passage 0 abundance. The plot on the right is labeled “dose dependent” and shows a species whose relative abundances at both passages 0 and 5 are sloped across mixture ratios.
goldmandoran.bsky.social
To do this, we mixed a set of in vitro gut microbial communities together at various initial ratios ranging over six orders of magnitude, and we used 16S sequencing to track the final relative abundances of each species after ~40 generations of growth.
A schematic representing mixtures of gut microbial communities at different ratios. Two culture flasks labeled “parent 1” and “parent 2” flank a set of vertical red and orange bars labeled with ratios 1000:1, 100:1, 10:1, 1:1, 1:10, 1:100, and 1:1000, with relative heights corresponding to these ratios. There are also solid red and orange bars on either side representing 1:0 and 0:1 ratios, respectively. Above the bars are written the number of replicates (2 for 1:0 and 0:1 ratios and 3 for all other ratios), and below the bars is written passage 5× (~40 generations).
goldmandoran.bsky.social
I’m thrilled to share my first ever publication, now published in PNAS! www.pnas.org/doi/10.1073/...

With mentorship from the amazing @ksxue.bsky.social, I looked at how the outcomes of species introductions to microbial communities are influenced by the number of introduced microbes.
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
Reposted by Doran Goldman
oozeley.bsky.social
shoutout to secretarybird, one of the most underrated birds
secretarybird absolutely serving while walking through some dry grass
goldmandoran.bsky.social
I feel incredibly lucky to have gotten to work with Katherine over the last five years, she’s a truly amazing and one of a kind mentor and person! Would highly encourage any interested students or postdocs to reach out to her!
ksxue.bsky.social
Hi friends new and old! I study how microbes interact and evolve in complex communities like the human gut microbiome.🦠🧬💩 I'm thrilled to share that I'm starting a lab at UC Irvine in April 2025 and am recruiting at all levels - please spread the word! kxuelab.com More about my work below...🧵1/n
Xue lab at UC Irvine
Ecology and evolution in the human gut microbiome
kxuelab.com
goldmandoran.bsky.social
I’d love to be added, thanks!
Reposted by Doran Goldman
ravenscimaven.bsky.social
I am mobilizing + giving free weekly science communication workshops in a private community for scientists + media who want to join the battle vs misinformation. I wasn't planning on doing this so soon but this is urgent. ALL scientists "hard" + "soft" DM with your credentials for details.
goldmandoran.bsky.social
I’d love to be added!
Reposted by Doran Goldman
mikeblazanin.bsky.social
Tried to put together a Microbial Evolution starter pack, but there were so many great people I didn't want to leave out it turned into 3 starter packs

Comment or DM me if you were missed or would like to be added!

A thread (1/3)

go.bsky.app/6pkuYhi