Gordon Matthewson
@gordonmatthewson.bsky.social
Dartmouth neurology PGY1 learning how to be a doc. Neuroimaging, neurophysiology/pathophysiology, new therapeutics, & proper techno music✌️
The precipitous drop in number of emails I need to pay attention to as a post-interview season but pre-match medical student feels a bit like being in the eye of a hurricaine. I'll take it
March 9, 2025 at 7:23 AM
The precipitous drop in number of emails I need to pay attention to as a post-interview season but pre-match medical student feels a bit like being in the eye of a hurricaine. I'll take it
Reposted by Gordon Matthewson
Metacognition of medical knowledge in LLMs: “Models consistently failed to recognize their knowledge limitations and provided confident answers even when correct options were absent.”
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Large Language Models lack essential metacognition for reliable medical reasoning - Nature Communications
Large Language Models demonstrate expert-level accuracy in medical exams, supporting their potential inclusion in healthcare settings. Here, authors reveal that their metacognitive abilities are under...
www.nature.com
February 12, 2025 at 8:23 PM
Metacognition of medical knowledge in LLMs: “Models consistently failed to recognize their knowledge limitations and provided confident answers even when correct options were absent.”
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Gordon Matthewson
A tour de force review of the connections between between the nervous and immune systems
www.nature.com/articles/s41...
www.nature.com/articles/s41...
February 12, 2025 at 4:29 PM
A tour de force review of the connections between between the nervous and immune systems
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Gordon Matthewson
jamanetwork.com/journals/jam...
Thread below👇
Thread below👇
Mapping Lesions That Cause Psychosis
This case-control study analyzes published cases of lesion-induced psychosisTo assess whether lesions that cause secondary psychosis have functional connections to a common brain circuit
jamanetwork.com
February 12, 2025 at 9:47 PM
jamanetwork.com/journals/jam...
Thread below👇
Thread below👇
Don't despair! Organize
February 3, 2025 at 8:20 AM
Don't despair! Organize
Reposted by Gordon Matthewson
I hope you will all join me in expressing your thanks to the NIH and NSF staff who are working in an impossibly difficult and chaotic environment to keep science going in our country.
February 3, 2025 at 1:45 AM
I hope you will all join me in expressing your thanks to the NIH and NSF staff who are working in an impossibly difficult and chaotic environment to keep science going in our country.
Reposted by Gordon Matthewson
US drug agency approves potent painkiller — the first non-opioid in decades
#MedSky 🧪
@nature.com
www.nature.com/articles/d41...
#MedSky 🧪
@nature.com
www.nature.com/articles/d41...
US drug agency approves potent painkiller — the first non-opioid in decades
The FDA’s nod for suzetrigine bolsters confidence in the pharmaceutical industry’s strategy to target sodium channels.
www.nature.com
January 31, 2025 at 7:05 AM
US drug agency approves potent painkiller — the first non-opioid in decades
#MedSky 🧪
@nature.com
www.nature.com/articles/d41...
#MedSky 🧪
@nature.com
www.nature.com/articles/d41...
Reposted by Gordon Matthewson
Every once in a while we publish a paper that moves a whole field forward. I think that's the case for this one from the Bugaj lab, where they describe proteins for THERMOGENETIC control of cellular behavior. www.nature.com/articles/s41...
A temperature-inducible protein module for control of mammalian cell fate - Nature Methods
The Melt (Membrane localization using temperature) protein translocates to the plasma membrane upon temperature shift. Melt variants with a range of switching temperatures enable straightforward therm...
www.nature.com
January 23, 2025 at 6:34 PM
Every once in a while we publish a paper that moves a whole field forward. I think that's the case for this one from the Bugaj lab, where they describe proteins for THERMOGENETIC control of cellular behavior. www.nature.com/articles/s41...
Reposted by Gordon Matthewson
A collaborative #openaccess review on how electrophysiological brain recording and imaging at multiple scales, from cells to large-scale brain networks, contribute to defining neurostimulation targets. #parkinson
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Electrophysiological approaches to informing therapeutic interventions with deep brain stimulation - npj Parkinson's Disease
npj Parkinson's Disease - Electrophysiological approaches to informing therapeutic interventions with deep brain stimulation
www.nature.com
January 24, 2025 at 2:50 AM
A collaborative #openaccess review on how electrophysiological brain recording and imaging at multiple scales, from cells to large-scale brain networks, contribute to defining neurostimulation targets. #parkinson
www.nature.com/articles/s41...
www.nature.com/articles/s41...
If/when I can afford a house, maybe moving to Pennsylvania, western New York, or Minnesota? shh #climatechange
Insurance cancellations, or 'non-renewals' in industry talk, are affecting homeowners across the country. The Senate Budget Committee forced insurers to disclose their data, so we now have a map of where the cancellations are happening. 🎁 link: www.nytimes.com/interactive/...
Insurers Are Dropping Homeowners as Climate Shocks Worsen
Without insurance, it’s impossible to get a mortgage; without a mortgage, most Americans can’t buy a home.
www.nytimes.com
December 28, 2024 at 6:57 AM
If/when I can afford a house, maybe moving to Pennsylvania, western New York, or Minnesota? shh #climatechange
Reposted by Gordon Matthewson
Honey, stop what you're doing, new hyponatremia research just dropped!
What's it say?
It looks like slow correction is associated with worse outcomes, like death and length of stay!
Was it just a small study?
No, it was a meta-analysis of almost 12,000 patients!
jamanetwork.com/journals/jam...
What's it say?
It looks like slow correction is associated with worse outcomes, like death and length of stay!
Was it just a small study?
No, it was a meta-analysis of almost 12,000 patients!
jamanetwork.com/journals/jam...
Correction Rates and Clinical Outcomes in Hospitalized Adults With Severe Hyponatremia
This systematic review and meta-analysis evaluates the association of sodium correction rates with mortality among hospitalized adults with severe hyponatremia.
jamanetwork.com
November 19, 2024 at 4:51 AM
Honey, stop what you're doing, new hyponatremia research just dropped!
What's it say?
It looks like slow correction is associated with worse outcomes, like death and length of stay!
Was it just a small study?
No, it was a meta-analysis of almost 12,000 patients!
jamanetwork.com/journals/jam...
What's it say?
It looks like slow correction is associated with worse outcomes, like death and length of stay!
Was it just a small study?
No, it was a meta-analysis of almost 12,000 patients!
jamanetwork.com/journals/jam...
Reposted by Gordon Matthewson
SUPER excited to share this opening for a senior (Assoc/Full) Professor of Psychiatry + endowed Chair at Dartmouth! You: a translational research scientist using imaging (fMRI, fNIRS, fUS) and/or neurostimulation (TMS, tTIS, tACS/DCS, tFUS). Please apply and repost!
tinyurl.com/dartmouthneuro
tinyurl.com/dartmouthneuro
DHMC and Clinics
providers-dartmouth-hitchcock.icims.com
December 18, 2024 at 1:48 AM
SUPER excited to share this opening for a senior (Assoc/Full) Professor of Psychiatry + endowed Chair at Dartmouth! You: a translational research scientist using imaging (fMRI, fNIRS, fUS) and/or neurostimulation (TMS, tTIS, tACS/DCS, tFUS). Please apply and repost!
tinyurl.com/dartmouthneuro
tinyurl.com/dartmouthneuro