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Reposted by Simon Grelet

bioRxivpreprint @biorxivpreprint.bsky.social · 9d

Identification of optimal fluorophores for use in the Drosophila embryo https://www.biorxiv.org/content/10.1101/2025.09.29.678560v1

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Simon Grelet @greletlab.bsky.social · Jul 28

Our work on intercellular transfer of mitochondria and cancer metastasis has been featured in Cancer Discovery, a journal of the American Association for Cancer Research @theaacr.bsky.social

📖 Read it here: aacrjournals.org/cdnews/news/...

Neurons Can Transfer Mitochondria to Cancer Cells

Cancer-associated neurons can transfer their mitochondria to cancer cells, boosting their metabolism and function. Mitochondria might also serve as a measure of risk of metastases. Future therapies co...

aacrjournals.org

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Simon Grelet @greletlab.bsky.social · Jul 22

🎉 NIH-MERIT Award (R37): I have received the NOA for my first R01 grant from the NIH. I am honored that it has been selected for conversion into an R37 MERIT Award, which allows funding for up to seven years! Learn more: grants.nih.gov/funding/acti...

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Simon Grelet @greletlab.bsky.social · Jul 3

🧠⚡ Check out this article about our work on mitochondrial transfers from nerves to cancer cells, recently featured in New Scientist.

www.newscientist.com/article/2485...

Cancer cells steal mitochondria from nerve cells to fuel their spread

Cancer cells can acquire energy-generating structures called mitochondria from nearby nerve cells, which seems to aid their spread, a discovery that could lead to new treatments

www.newscientist.com

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Simon Grelet @greletlab.bsky.social · Jul 1

Thanks for sharing!

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Reposted by Simon Grelet

Albert and Mary Lasker Foundation @laskerfdn.bsky.social · Jun 30

The @greletlab.bsky.social show enhanced metastatic capabilities of cancer cells that receive mitochondria from neurons in primary tumors, shedding new light on how the nervous system supports cancer metabolism and metastatic dissemination.

Nerve-to-cancer transfer of mitochondria during cancer metastasis

A study reports the development of a method to trace intercellular transfer of mitochondria, and demonstrates that cancer cells that receive mitochondria from neurons have enhanced metastatic capabilities.

www.nature.com

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Reposted by Simon Grelet

Diana Fulmer @dianafulmer.bsky.social · Jun 27

Did you know that sea slugs steal chloroplasts from algae as portable snacks?! Neither did I, but a new Cell paper demonstrates that they do. 🐌🧪

My favorite part is the researchers called the storage for these stolen hors d’oeuvres “kleptosomes” 😂🥰

Summary from Nature & Cell paper linked below.

‘Wildest thing’: solar-powered slug steals chloroplasts and stores them for emergencies

Marine creatures house contraband structures in special organelles, which the animal raids for food in times of need.

www.nature.com

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Reposted by Simon Grelet

Jeremy Borniger @jborniger.bsky.social · Jun 27

Center of Rho ophiuchi cloud complex, 7.5h LRGB. #astrophotography

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Simon Grelet @greletlab.bsky.social · Jun 27

Thanks Jeremy! Hope to see you soon. I enjoyed our discussions in Houston last year.

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Simon Grelet @greletlab.bsky.social · Jun 27

Here is an interesting and detailed highlight of our work.
"Neuronal transfer of mitochondria to tumour cells promotes cancer spread"
- News and views - section of Nature.
www.nature.com/articles/d41...

Neuronal transfer of mitochondria to tumour cells promotes cancer spread

Neurons often receive organelles called mitochondria from other cells. It emerges that neurons donate mitochondria that support cancer-cell spread.

www.nature.com

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Simon Grelet @greletlab.bsky.social · Jun 27

Check out our work highlight in the "News" section of Nature.
"Cancer cells get power boost by stealing mitochondria from nerves"
www.nature.com/articles/d41...

Cancer cells get power boost by stealing mitochondria from nerves

The theft probably helps the cells to spread around the body, and preventing it could provide a path to treatment, researchers say.

www.nature.com

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Simon Grelet @greletlab.bsky.social · Jun 26

www.science.org/content/arti...

Tumors may get supercharged by acquiring powerhouses of nerve cells

Scientists spot mitochondria traveling through “bridges” into nearby cancer cells

www.science.org

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Reposted by Simon Grelet

Jean Nakhle @jeannakhle.bsky.social · Jun 26

When I began studying mitochondria transfer during my master's internship in 2016, a committee member dismissed it as artificial and irrelevant to (patho)physiology. It's great to see growing evidence from recent studies proving otherwise 😊

Nature @nature.com · Jun 25

Nature research paper: Nerve-to-cancer transfer of mitochondria during cancer metastasis

https://go.nature.com/46c474I

Nerve-to-cancer transfer of mitochondria during cancer metastasis - Nature

A study reports the development of a method to trace intercellular transfer of mitochondria, and demonstrates that cancer cells that receive mitochondria from neurons have enhanced metastatic capabilities.

go.nature.com

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Simon Grelet @greletlab.bsky.social · Jun 26

Happy to share our latest study is now out in Nature!

Cancer cells steal mitochondria from neurons to boost metabolism, resist stress & spread.

www.nature.com/articles/s41...

#CancerGetsNervous #Metastasis #Mitochondria #Neuron #CancerResearch #Nature