Lightnews — Scholar-powered news

Jeremy Borniger @jborniger.bsky.social · 19h

The Pleiades

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Jeremy Borniger @jborniger.bsky.social · 1d

Prem is it known how many of these kids are still alive?

Reposted by Jeremy Borniger

Christophe 🔬 L @christlet.bsky.social · 22d

Our new preprint is up! This is the main postdoc work of @wiesner-t.bsky.social focusing on exocytosis along the axon shaft and its regulation by the sub membrane actin-spectrin scaffold: www.biorxiv.org/content/10.1...
Read the thread below for a summary of our findings 🧵1/11

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Jeremy Borniger @jborniger.bsky.social · 21d

Are you at the meeting? If so come say hi ! 👋

Reposted by Jeremy Borniger

Current Biology @currentbiology.bsky.social · Sep 7

David Baltimore, giant of molecular biology, has died.

Matthew Cobb @matthewcobb.bsky.social · Sep 7

Co-discoverer of reverse transcriptase at 32, Nobel Prize at 37, played a key role at the 1975 Asilomar comference.

David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87

www.nytimes.com

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Jeremy Borniger @jborniger.bsky.social · Sep 6

Mine are in here too. Instead of money, I would accept a complete dismantling of the current world order…if that’s easier.

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Jeremy Borniger @jborniger.bsky.social · Sep 6

www.biorxiv.org/content/10.1... new preprint from the lab where stellar postdoc @alixbattison.bsky.social demonstrates that two common proximity labeling approaches enrich different proteomes when localized to the same cellular compartments. Important implications for discovery proteomics.

APEX2 and TurboID define unique subcellular proteomes

Proximity labeling has emerged as a prominent, reliable tool for obtaining local proteomes from a wide range of cell-types. Two major classes of labeling reagents, peroxidase based (APEX family), or b...

www.biorxiv.org

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Reposted by Jeremy Borniger

Gutmann Lab @gutmannlab.bsky.social · Sep 3

Exciting news! Our new paper is out in Neuron! We discovered how neurons drive brain tumor growth through aberrant glutamate–tyrosine kinase signaling, uncovering novel mechanisms that shape tumor progression. Grateful to our team & collaborators for making this breakthrough possible! 🧠✨

Aberrant coupling of glutamate and tyrosine kinase receptors enables neuronal control of brain-tumor growth

Anastasaki and colleagues establish a previously unknown glutamate growth dependency in pediatric low-grade brain tumors (gliomas). Glioma cells hijack normal neuron-glial molecular circuits present d...

www.cell.com

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Jeremy Borniger @jborniger.bsky.social · Aug 26

Andromeda (M31) in LRGBHa (~24.5h) #astrophotography

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Reposted by Jeremy Borniger

Anonymous @youranoncentral.bsky.social · Aug 11

Thousands of brave people from all over DC have taken to the streets to protest the illegal military occupation by the Jeffrey Epstein associate, 36 time convicted felon and rapist, Donald Trump. #3E #removeTrump #freeDC (📹 @Ronxyz00)

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Reposted by Jeremy Borniger

Kristian G. Andersen @kgandersen.bsky.social · Aug 7

This is literally some of the craziest shit I have ever read.

And that's saying a lot.

www.whitehouse.gov/presidential...

Improving Oversight of Federal Grantmaking

By the authority vested in me as President by the Constitution and the laws of the United States of America, and to improve the process of Federal

www.whitehouse.gov

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Jeremy Borniger @jborniger.bsky.social · Aug 7

Nice synapse from synaptosome prep. From @mayywu.bsky.social :))) can see presynaptic vesicles and clear PSD.

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Reposted by Jeremy Borniger

Megan Ranney MD MPH @meganranney.bsky.social · Jul 29

A little known - but hugely consequential - part of the government’s changes to science funding:

open.substack.com/pub/sciencea...

A Quiet Policy Shift That Could Devastate American Science

Why NIH’s sudden move to multi-year grant funding should alarm every principal investigator and university

open.substack.com

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Jeremy Borniger @jborniger.bsky.social · Jul 28

Evil shithead.

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Reposted by Jeremy Borniger

Hannah Meyer @hannahvmeyer.bsky.social · Jul 25

Check out how we tackled one of the fundamental challenges in immunology, out today @cp-cellsystems.bsky.social: www.cell.com/cell-systems.... Our major innovations are BATCAVE and BATMAN, two new players to get us closer to solving TCR-pMHC predictions!

T cell receptor cross-reactivity prediction improved by a comprehensive mutational scan database

Banerjee et al. present a comprehensive T cell receptor cross-reactivity database and a hierarchical Bayesian framework to predict T cell receptor targets. Together, they reveal structural and biochem...

www.cell.com

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Reposted by Jeremy Borniger

Ashani Weeraratna @ashi-w.bsky.social · Jul 24

May the odds be ever in your favor.
4% payline at the NCI.

www.cancer.gov/grants-train...

Funding Policy - Research Grants

NCI funding policy for research project grant (RPG) awards reflects the funding goals of the institute, NIH, and HHS.

www.cancer.gov

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Reposted by Jeremy Borniger

Jose M. Adrover @adrover.bsky.social · Jul 17

I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...

Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature

Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.

www.nature.com

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Reposted by Jeremy Borniger

Dr James Morris @drjamesmorris.bsky.social · Jul 15

Prasad is UCSFs failure

Jonathan Howard @joho.bsky.social · Jul 15

An oncologist who botches basic facts and thinks temporary vaccine side effects are worse than death is imposing his will on millions of Americans.

July 15, 2025 01:50 PM EDT-Pharma, FDA+, Coronavirus
Prasad again overrode
FDA vaccine reviewers, this time on Moderna's Covid shot for young kids
Max Bayer
Pharma Reporter
The FDA's vaccines and biologics chief Vinay Prasad overrode the agency's vaccine reviewers for a third time in recent

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Reposted by Jeremy Borniger

Jeremy Berg @jeremymberg.bsky.social · Jul 15

A discussion of the use of animals in research.

www.youtube.com/watch?v=iSvk...

1/n

(Warning: Rant coming)

Director’s Desk: The Future of Animal Models in Research | NIH’s Dr. Nicole Kleinstreuer

YouTube video by National Institutes of Health (NIH)

www.youtube.com

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Reposted by Jeremy Borniger

John Tuthill @tuthill.bsky.social · Jul 14

i wrote an essay for @thetransmitter.bsky.social about what it feels like to serve on an NIH grant review panel (study section) right now

www.thetransmitter.org/craft-and-ca...

Fear and loathing on study section: Reviewing grant proposals while the system is burning

As grants are canceled, delayed and subject to general uncertainty, participating in study sections can feel futile. But it’s more important than ever.

www.thetransmitter.org

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Reposted by Jeremy Borniger

Angela Collier @acollierastro.bsky.social · Jul 11

immigration is good actually.

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Jeremy Borniger @jborniger.bsky.social · Jul 11

Visiting Santiago Ramon y Cajal’s house in Barcelona featuring @erikherzog.bsky.social , Charo Robles & Luis de Lecea :))) neuroscience pilgrimage

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Reposted by Jeremy Borniger

Democracy Now! @democracynow.org · Jul 11

Former NOAA official Monica Medina says the scale of death and destruction from catastrophic flooding in Texas was "entirely preventable," faulting budget cuts for hampering preparedness.

"Many of those lost lives could have been saved if links in our disaster response chain hadn't been broken."

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Jeremy Borniger @jborniger.bsky.social · Jul 9

#chronobiologyGRC in Barcelona

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Reposted by Jeremy Borniger

BWJones @bwjones.bsky.social · Jul 3

ICE now has a budget bigger than the United States Marine Corps.

ICE now has a budget bigger than what we spend on biomedical research in America.

This is sociopathic to the extreme.

Alexandria Ocasio-Cortez @aoc.bsky.social · Jul 3

I don’t think anyone is prepared for what they just did w/ ICE.

This is not a simple budget increase. It is an explosion - making ICE bigger than the FBI, US Bureau of Prisons, DEA,& others combined.

It is setting up to make what’s happening now look like child’s play. And people are disappearing.

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