Please RT:
We have an opening for a junior group leader position in „Phage Biology & Biotechnology“.
www.fz-juelich.de/de/karriere/...

Interested candidates are encouraged to contact me via email for further details.

@spp2330.bsky.social; @mibinet.bsky.social

Really excited to share our latest work led by @mattiaubertini.bsky.social and @nesslfy.bsky.social: we report that cohesin loop extrusion creates rare but long-lived encounters between genomic sequences which underlie efficient enhancer-promoter communication.
www.biorxiv.org/content/10.1...
A🧵👇

Apply now for FBM #PhD #Fellowships in #Life #Sciences – join one of the Faculty’s leading laboratories.

🚨 Application deadline for fellowships: October 6, 2025.
➡️ www.unil.ch/news/en/1756...

@unil.bsky.social @dmf-unil.bsky.social @dee-unil.bsky.social @dib-unil.bsky.social #fbm #unil

Hey hey hey!
Tomorrow, September 16th at 16:00 UTC, don’t miss the next ISPB virtual seminar!
This session will focus on plasmid elimination with great speakers lined up.

#Plasmid #ISPB #MGEs

Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer

We are hiring-join us!

Thanks to all the reviewers and the editor for their constructive comments and support.

Our Wadjet-II paper by @roisnehamelinf.bsky.social is out in polished form: www.cell.com/structure/fu...

With a great preview by @kevincorbett.bsky.social & @amardeeep.bsky.social highlighting the potential of Wadjets:

Wadjet—Keeping a watchful eye on circular DNA.

www.cell.com/structure/fu...

Congratulations Rotem Sorek @soreklab.bsky.social on receiving the Gruber prize today in Stockholm

#phagesky

I am looking for phages infecting Streptococcus pneumoniae to test a phenotype - does anyone have some and willing to share ?

Repost appreciated :)

Recurrent acquisition of nuclease-protease pairs in antiviral immunity https://www.biorxiv.org/content/10.1101/2025.07.28.667249v1

🧬 Ever wonder how metres of #DNA 🧬 fit into a single cell?

@gruberlab.bsky.social, working at @unil.bsky.social uncovered how protein machines fold DNA into loops – key for cell division & genome stability.

Learn more 👉 buff.ly/PrfdXnr

#BioTech #Chromosomes #Crystallography #GeneEditing 🧪

Excited to share a new preprint from the lab with @ryandhindsa.bsky.social ! www.biorxiv.org/content/10.1...

Led by @sherrynyeo.bsky.social, @erinmayc.bsky.social, and friends, we continue our journey to find viral DNA in our favorite place-- the overlooked and discarded reads in existing data! 1/

🔔Paper alert! Extremely excited to share a preprint from our lab! Spearheaded by @axel-schmidt.bsky.social, a super talented medical & computational geneticist, we studied latent Epstein-Barr virus (EBV) infection at population-scale.

Interested in how this works & what we found? Read along! 👇

Still a spicy question! Cohesin rings can hold sister mini-chromosomes (CEN plasmids isolated from yeast) together by "embracing" them. See beautiful work by Kim Nasmyth lab...

What happens on real chr is less clear & maybe more complicated... Calling in the real expert @dnatopologylab.bsky.social

BPS is in San Francisco next year! www.biophysics.org/2026meeting

AI just cracked de novo antibody design with a 100x leap! 🧪

Chai-2, a next-gen multimodal generative model, is shaking up protein design. With a 16% hit rate in fully de novo antibody design—over 100 times better than previous methods—it’s making drug discovery faster and more precise than ever.

🚨New preprint🚨We developed a transverse flow imaging approach to directly visualize bacterial replisomes challenged by topological barriers and discovered a fast rotational mode of replisome operation. Fantastic work by thomasmretzer.bsky.social and Hamdan Lab! tinyurl.com/replisomerot...

Structural insights into type I and type II Lamassu anti-phage systems https://www.biorxiv.org/content/10.1101/2025.06.23.660979v1

Dear Mobile DNA Researchers,

The 8th Woods Hole Mobile Genetic Elements meeting will be held Aug 28 to Aug 30, 2025, at the MBL in Woods Hole, Massachusetts.

Info, registration, and abstract submission: www.eventsquid.com/event/28372

#MobileDNA #MobileGeneticElements

Great job opportunity at The Center for Integrative Genomics, Lausanne University, Switzerland unil.ch/cig/en/home....
For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareer...

Ah, thanks for letting me know. I have preposted with the correct link.

This reveals parallels with DNA end protection in eukaryotes and highlights the challenges of having linear chromosomes as well as functional repair of DNA double strand break.

www.biorxiv.org/cgi/content/...

Maya, with help from Ania and Nicolas, figured out that the phage-encoded telomere resolvase TelN, which generates hairpin telomeres in the first place, also protects them from degradation by E. coli MR nuclease (but not B. subtilis MR). TelN associates with telomeric DNA and directly inhibits MR.