Lightnews — Scholar-powered news

Guigó Lab @guigolab.bsky.social · 4d

Avui hem obert les portes de la nostra recerca als visitants de l’ #OpenPRBB 🔬🪰🧬 Sempre amb molta il·lusió! @crg.eu @prbb.org

1 3

Reposted by Guigó Lab

Arnau Sebé-Pedrós @arnausebe.bsky.social · 14d

Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...

2 110 220

Guigó Lab @guigolab.bsky.social · 16d

🌍✨ Master’s project in our Lab @crg.eu
🌱🧬 Help build the Biodiversity Long-Read Transcriptomic Catalogue @ebpgenome.bsky.social with @pacbio.bsky.social & @nanoporetech.com

💻 Python/R, Linux, seq data
💶 600€/mo + travel
📩 [email protected] / [email protected]
ℹ️ www.crg.eu/en/content/t...

Centre for Genomic Regulation Website

www.crg.eu

2 3

Guigó Lab @guigolab.bsky.social · Jul 28

🚨 We are hiring a Postdoc @crg.eu! 🧬
 Within the EU-funded #PrecisionTox project. We are developing computational methods to predict toxicity by integrating RNA-seq data from humans and model species 🪱🪰🐸🐠. The project will help replace animal testing.

🔗 Apply now: recruitment.crg.eu/content/jobs...

Post-Doctoral Researcher for Precision Tox | CRG Online Recruitment Portal

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

recruitment.crg.eu

2 6

Guigó Lab @guigolab.bsky.social · Jul 24

🎉 We’ve earned Bronze LEAF Accreditation for our efforts to make lab work more sustainable @crg.eu! By joining @ucl.ac.uk Laboratory Efficiency Assessment Framework, we are committed to improving efficiency and reducing our environmental impact. 🌱🔬

3

Guigó Lab @guigolab.bsky.social · Jul 18

🎓 Huge congrats to our two @bist.eu Master’s students, Igor Trujnara and @rebeccawallis.bsky.social who successfully defended their theses this week!

🧬💻Igor explored Large Language Models for genome annotation, while Rebecca investigated microbial biodiversity in Pyrenean lakes🏔️.

@crg.eu @upf.edu

1 3 7

Guigó Lab @guigolab.bsky.social · Jul 16

🚴🏻🚴🏻‍♀️🚴🏻‍♂️ Read about Ana, Fabio & Nadja’s journey to the LongTREC Summer School in Norwich!
#LongTREC #ScienceOnTheMove #SustainableScience #Bioinformatics #ScienceLife

Conesa Lab @conesalab.bsky.social · Jul 15

Checkout our latest blogpost, with a recap of @anaconesa.bsky.social amazing trip to reach Norwich!

conesalab.uv.es/longtrec_of_...

Sustainability on Action | Genomics of Gene Expression

It all began as the best ideas begin, with a simple yet effective What if… ? One day Ana asked us and herself, What if we were more active towards sustainability when travelling? How can I bring…

conesalab.uv.es

1 2

Guigó Lab @guigolab.bsky.social · Jul 16

Great to see our PhD student Fabio Zanarello sharing his work yesterday at LongTREC summer school!
#LongReadsTranscriptomics #LongTREC #GenomeAnnotation #Bioinformatics #EarthBioGenomeProject
@crg.eu

LongTREC @longtrec.bsky.social · Jul 15

Fabio Zanarello has a goal in his session: explain how #LongReads sequencing is integrated in the non-model genome annotation workflow.

#LongReadsTranscriptomics #LongTREC #GenomeAnnotation #Bioinformatics #EarthBioGenomeProject

2 2

Reposted by Guigó Lab

Ana Conesa @anaconesa.bsky.social · Jul 12

We made it!!!! València-London by train. London-Norwich by bike!!!

4 20

Reposted by Guigó Lab

LongTREC @longtrec.bsky.social · Jul 11

First journey done! 🌟 Our amazing cyclists arrived safely in Cambridge — still smiling! 😄🚴‍♀️ More than the ride: sustainability, team spirit & pushing limits. They’re recharging now… and ready for the next leg! #LongCyclingForScience #TeamSpirit
@anaconesa.bsky.social #LeadingByExample

3 6

Reposted by Guigó Lab

LongTREC @longtrec.bsky.social · Jul 12

Not everyone can or wants to cycle for 2–3 days, but we can all take a moment to ask ourselves:

💡 “How much am I impacting the planet with this trip?”
💡 “What can I do to reduce that impact?”

@anaconesa.bsky.social

#LongCyclingForScience #SustainableScience #LongReadsTranscriptomics

4 7

Guigó Lab @guigolab.bsky.social · Jul 11

🚴 From @crg.eu to the roads of Europe, our PhD student Fabio and the #LongTREC team are combining cutting-edge science with sustainable travel.

Now in London, and heading next to Cambridge! #LongCyclingForScience

LongTREC @longtrec.bsky.social · Jul 11

Our #LongTREC cycling superstars have reached London! And they have brought the stunning sunny weather with them ☀️! Next stop : Cambridge.

#LongReadsTranscriptomics #LongCyclingForScience #SustainableScience

3 7

Guigó Lab @guigolab.bsky.social · Jul 11

🚴‍♂️🌍 Excited to see our PhD student Fabio Zanarello featured in the #LongTREC video series! 👏

Don’t miss the video and learn more about #LongTREC #LongReadsTranscriptomics and #LongCyclingForScience.

#SustainableScience #Bioinformatics #PhDLife

@crg.eu

LongTREC @longtrec.bsky.social · Jul 11

Continuing our LongTREC video series, we’re excited to feature Fabio Zanarello from @crg.eu in this next episode.
#LongReadsTranscriptomics #LongCyclingForScience #SustainableScience

2 4

Reposted by Guigó Lab

Ana Conesa @anaconesa.bsky.social · Jul 10

This is going to be so much fun!!! Do not miss our #LongCyclingForSciene adventure! from Valencia to Norwich by train & bike, posting about science and bcsustainability @pacbio.bsky.social @nanoporetech.com @iscb.bsky.social @csic.es @hitseq.bsky.social @bcbhubcsic.bsky.social @sebibc.bsky.social

LongTREC @longtrec.bsky.social · Jul 10

We’re kicking off a video series to showcase our network and its mission.
🎥 Watch @anaconesa.bsky.social introducing our project and why raising sustainability awareness in science is so important.

@i2sysbio.es @csic.es
#LongCyclingForScience 🚴🌎
#LongReadsTranscriptomics 🔬 #Outreach4Science ✍

5 7

Guigó Lab @guigolab.bsky.social · Jul 2

📊 RNA localization matters for gene regulation. We present a method to estimate transcript distributions between nucleus & cytosol using nuclear, cytosolic and whole-cell RNAseq.

🔵🧬 doi.org/10.1093/narg...

@crg.eu @rodericguigo.bsky.social

Studying relative RNA localization from nucleus to the cytosol

Abstract. The precise coordination of important biological processes, such as differentiation and development, relies heavily on the regulation of gene exp

doi.org

1 2

Reposted by Guigó Lab

Pau Clavell-Revelles @pclavell.bsky.social · May 30

I am so happy to learn that I won the Early Career Award for an outstanding presentation at the ESHG!!
Thanks to @melelab.bsky.social, @guigolab.bsky.social and to my awesome colleagues that also attended the conference for their support @rubenchazarra.bsky.social @ramirezjmiguel.bsky.social

2 3

Guigó Lab @guigolab.bsky.social · May 14

Our lab had dual presence at #BoG25 @cshlmeetings.bsky.social!
🧬 Silvia González-López spoke on chromatin dynamics & transcriptional regulation.
🌍 @fairlie.bsky.social presented ancestry-aware gene annotations — a @guigolab.bsky.social × @melelab.bsky.social collab:
www.biorxiv.org/content/10.1...

3 7

Guigó Lab @guigolab.bsky.social · May 12

Exciting day in the lab, congratulations to Dr. Ntasis on successfully defending! 🎓🥳

2

Reposted by Guigó Lab

Rebecca Wallis D @rebeccawallis.bsky.social · May 8

Had a great time at the Computational Symposium- such a valuable opportunity to connect with colleagues, hear about exciting projects, and share progress on my master’s research! Presenting my work on the Pyrenean Lake microbiome has been invaluable for gathering feedback and ideas for my analysis 🙂

Guigó Lab @guigolab.bsky.social · Apr 30

This week, we had a great time attending the 19th Computational Genomics Symposium at @prbb.org, a very nice opportunity to catch up with colleagues 💻🧬☀️
@crg.eu

1 3

Guigó Lab @guigolab.bsky.social · Apr 30

This week, we had a great time attending the 19th Computational Genomics Symposium at @prbb.org, a very nice opportunity to catch up with colleagues 💻🧬☀️
@crg.eu

3

Reposted by Guigó Lab

UCSC Genome Browser @genomebrowser.bsky.social · Mar 25

A new hub has been added to the Public Hubs listing, EPIration - an atlas of candidate enhancer-gene interactions in human tissues and cell lines.

View this hub using the following URL:
genome.ucsc.edu/cgi-...

We want to thank the @guigolab.bsky.social for making this data available.

1 1

Guigó Lab @guigolab.bsky.social · Mar 22

🚀 Our new paper is out! The BioGenome Portal: an open-source customizable platform for managing biodiversity genomics data 🧬🌍

doi.org/10.1093/narg...

@crg.eu @rodericguigo.bsky.social

#genomics #biodiversity

The BioGenome Portal: a web-based platform for biodiversity genomics data management

Abstract. Biodiversity genomics projects are underway with the aim of sequencing the genomes of all eukaryotic species on Earth. Here we describe the BioGe

academic.oup.com

6 12

Reposted by Guigó Lab

Marta Melé @martamele.bsky.social · Mar 20

This has been a fantastic collaboration with @guigolab.bsky.social and led by @pclavell.bsky.social & @fairlie.bsky.social where we show something we suspected for some time: human gene annotations are European-biased, read this thread to know more about this work @bsc-cns.bsky.social @crg.eu

Melé Lab @melelab.bsky.social · Mar 20

Do you work in 💫human genetics💫?
Have you ever worried about what’s inside your gene annotation GTF⁉️

WELL, YOU SHOULD! 😱
Especially when studying a genetically diverse 🌍 cohort!

🔴We discover that gene annotations are European-biased 👉 impacting downstream analyses!

Don't miss this thread🧵⬇️
1/13

Long-read transcriptomics of a diverse human cohort reveals widespread ancestry bias in gene annotation

Accurate gene annotations are fundamental for interpreting genetic variation, cellular function, and disease mechanisms. However, current human gene annotations are largely derived from transcriptomic...

www.biorxiv.org

2 10

Reposted by Guigó Lab

Pau Clavell-Revelles @pclavell.bsky.social · Mar 20

I never thought that I would wear again the lab coat 🥼 but I did it to sequence RNA with @nanoporetech.com at @guigolab.bsky.social . Thanks to @scarbonells.bsky.social , Carme and Zighi for their great teachings and patience in the wetlab. They definitely have solutions for everything!

Melé Lab @melelab.bsky.social · Mar 20

Do you work in 💫human genetics💫?
Have you ever worried about what’s inside your gene annotation GTF⁉️

WELL, YOU SHOULD! 😱
Especially when studying a genetically diverse 🌍 cohort!

🔴We discover that gene annotations are European-biased 👉 impacting downstream analyses!

Don't miss this thread🧵⬇️
1/13

Long-read transcriptomics of a diverse human cohort reveals widespread ancestry bias in gene annotation

Accurate gene annotations are fundamental for interpreting genetic variation, cellular function, and disease mechanisms. However, current human gene annotations are largely derived from transcriptomic...

www.biorxiv.org

2 5

Reposted by Guigó Lab

Melé Lab @melelab.bsky.social · Mar 20

Do you work in 💫human genetics💫?
Have you ever worried about what’s inside your gene annotation GTF⁉️

WELL, YOU SHOULD! 😱
Especially when studying a genetically diverse 🌍 cohort!

🔴We discover that gene annotations are European-biased 👉 impacting downstream analyses!

Don't miss this thread🧵⬇️
1/13

Long-read transcriptomics of a diverse human cohort reveals widespread ancestry bias in gene annotation

Accurate gene annotations are fundamental for interpreting genetic variation, cellular function, and disease mechanisms. However, current human gene annotations are largely derived from transcriptomic...

www.biorxiv.org

3 13 30