Bilal Haider
@haiderlab.bsky.social
1.7K followers 290 following 88 posts
Neurons, circuits, visual perception | Associate Professor, Georgia Tech & Emory University, Atlanta, USA | haider.gatech.edu Posting about #neuroscience research, mentoring, science advocacy.
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haiderlab.bsky.social
(1/10) Happy to share a science update! 🧠🧪
Our @natureneuro.bsky.social article shows how inhibitory neurons calculate “subtraction” or “division” to adjust visual sensitivity!
This one has it all – behavior, optogenetics, modeling, cell types, subthreshold mechanisms. Quick thread 🧵below
Lateral inhibition in V1 controls neural and perceptual contrast sensitivity - Nature Neuroscience
The role of lateral inhibition for perception and neural computation remains unsolved. Del Rosario et al. show that distinct types of cortical interneurons in V1 drive lateral inhibition that causes s...
doi.org
Reposted by Bilal Haider
roordalab.bsky.social
This paper is the result of >20 yrs of hard work by talented students, postdocs and collaborators, but none more than my co-author Ren Ng and his team in EECS.
1/n
Novel color via stimulation of individual photoreceptors at population scale | Science Advances www.science.org/doi/10.1126/...
Novel color via stimulation of individual photoreceptors at population scale
Image display by cell-by-cell retina stimulation, enabling colors impossible to see under natural viewing.
www.science.org
Reposted by Bilal Haider
pjsjostrom.bsky.social
🧪 The Sjöström Lab in Montreal is looking for a postdoc! We study cortical circuits, synaptic plasticity, and NMDAR signalling using custom 2-photon microscopy and optogenetics. We seek candidates with strong patch-clamp and/or 2-photon imaging expertise, and a relevant publication track record.
We are looking for an outstanding postdoctoral researcher to join our team at McGill University. The Sjöström lab studies neocortical circuits, with a focus on synaptic plasticity, NMDA receptor signaling, 2-photon optogenetics, and advanced 2-photon imaging. We are particularly interested in candidates with strong expertise in whole-cell patch-clamp electrophysiology and/or 2-photon imaging, and a solid track record of relevant publications.
Applicants should be experienced with whole-cell recordings and/or cutting-edge imaging approaches. Responsibilities will include performing experiments, analyzing and presenting data locally and internationally, writing manuscripts, and occasionally mentoring junior lab members.
Our lab is based at the Research Institute of the McGill University Health Centre, in vibrant, multicultural Montreal—a city that offers exceptional quality of life. McGill and its neighbouring universities form one of the most dynamic neuroscience communities in the world.
For examples of our current directions, see:
•	Chou et al The Innovation 2025, www.cell.com/the-innovation/fulltext/S2666-6758(24)00173-5
•	Wong et al Neuron 2024, www.cell.com/neuron/fulltext/S0896-6273(23)00767-5
The position is fully funded with a competitive salary. Candidates are also expected to apply for external funding, for which we provide strong support. Opportunities are available for both Canadian and international applicants.
To apply, please send a Letter of Intent, CV, brief research statement, and contact information for three referees to Dr. Jesper Sjöström (jesper.sjostrom@mcgill.ca). In the subject line, include "Postdoc" followed by your name.
Application deadline: July 31, 2025. 
Website: http://plasticity.muhc.mcgill.ca
McGill University is committed to diversity and equity in employment.
Reposted by Bilal Haider
Reposted by Bilal Haider
caswell.bsky.social
Anyone looking for a PhD in NeuroAI (models of the visual system to spatial system)? @amansaleem.bsky.social and I are looking for someone to start in October. More details here: www.findaphd.com/phds/project...

Get in touch with either of us if you’ve got questions!
Computational Neuroscience, NeuroAI PhD at UCL at University College London on FindAPhD.com
PhD Project - Computational Neuroscience, NeuroAI PhD at UCL at University College London, listed on FindAPhD.com
www.findaphd.com
Reposted by Bilal Haider
bita137.bsky.social
FDA plans to phase out animal testing requirement for drug testing and replace it with “AI-based computational models of toxicity” and organoid toxicity testing www.fda.gov/news-events/...
FDA Announces Plan to Phase Out Animal Testing Requirement for Monoclonal Antibodies and Other Drugs
FDA Plans to Phase Out Animal Testing Requirement
www.fda.gov
Reposted by Bilal Haider
drannabellesinger.bsky.social
Check out our latest paper today in Nature: “Goal specific hippocampal inhibition gates learning” www.nature.com/articles/s41...
By Nuri Jeong, Xiao Zheng, Abby Paulson, Steph Prince and colleagues.
Reposted by Bilal Haider
alleninstitute.org
How does the brain work?

Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵

🧠📈
Reposted by Bilal Haider
avisfavaro.bsky.social
Brain gain? Toronto's @UHN hospital system will announce a strategy to attract U.S. health scientists - plan to be unveiled Monday.
Website isn't up yet, but U.S scientists interested check here Monday. Hopefully other hospitals & universities follow UHNCanadaleads.ca
a canadian flag with a red maple leaf in the middle
ALT: a canadian flag with a red maple leaf in the middle
media.tenor.com
Reposted by Bilal Haider
alexkwan.bsky.social
This was a difficult thread to write..

Our research on antidepressants has been supported by NIMH for 10 years. Until the last moment, their comms team was still trying to put out a press piece about this work for us. I’m so sorry.
alexkwan.bsky.social
Our latest study identifies a specific cell type and receptor essential for psilocybin’s long-lasting neural and behavioral effects 🍄🔬🧠🧪

Led by Ling-Xiao Shao and @ItsClaraLiao

Funded by @NIH @NIMHgov

📄 Read in @nature.com - www.nature.com/articles/s41...

1/12
Psilocybin’s lasting action requires pyramidal cell types and 5-HT2A receptors - Nature
A pyramidal cell type and the 5-HT2A receptor in the medial frontal cortex have essential roles in psilocybin’s long-term drug action.
www.nature.com
Reposted by Bilal Haider
katejj.bsky.social
OK here it is, the moment you have all been waiting for! Our advert for 5 posts here at Glasgow: Cognitive neuroscience/psychology. Closing date May 12 - please spread the word
www.nature.com/naturecareer...
haiderlab.bsky.social
Agreed - most units should be many synapses away from V1, but some still fire as quickly (see S4e: av. latency includes long 'tail' of slower units). Lots to figure out!
Reposted by Bilal Haider
gbouvier.bsky.social
Interesting work by Tony Lien & @haiderlab.bsky.social. They reveal how some frontal cortex neurons mirrors V1 neurons. Responses lag visual cortex (VC) by ~25ms, with strikingly similar receptive fields—yet lacking a topographic map. Crucially, silencing VC abolishes these responses. Congrats
haiderlab.bsky.social
Exciting new results from the lab -- *visual* receptive fields in motor and cingulate cortex! Great work from Tony Lien 🧠🧪
haiderlab.bsky.social
Congrats to Kayla Peelman on publishing her paper AND defending her thesis in the same week ✨🎉
Click 👇 to see how the environment shapes the timing and selectivity of vision 👁️🧠🧪
www.cell.com/current-biol...
Reposted by Bilal Haider
jeremymberg.bsky.social
Compelling pushback from @jmgrohneuro.bsky.social and the Board of Scientific Counselors at the National Institute on Mental Health (NIMH) regarding termination of tenure-track investigators driven by DOGE.

1/2
Reposted by Bilal Haider
deisseroth.bsky.social
Congratulations to these two outstanding physician-neuroscientists! Many people now are familiar with the fascinating fundamental research of @michellemonje.bsky.social but most people probably don't know she is a truly great physician. I'm fortunate to be inspired by her every day, in every way.
brainprize.org
Congratulations to winners of The Brain Prize 2025!
Professors @michellemonje.bsky.social, @stanfordmedicine.bsky.social and @hhmi.org Investigator, and Frank Winkler, Heidelberg University Hospital, have pioneered the field of Cancer Neuroscience.

Learn more: brainprize.org/winners/canc...
haiderlab.bsky.social
Super interesting... phenotyping social behavior + touch in 7 monogenic rat models of autism
olveczky.bsky.social
Excited to present the latest from the lab out today in Cell www.cell.com/cell/fulltex.... See Thread! 1/8
haiderlab.bsky.social
just noticed @jdelrosario.bsky.social has joined us here - welcome and congrats on a great study 👇
haiderlab.bsky.social
(1/10) Happy to share a science update! 🧠🧪
Our @natureneuro.bsky.social article shows how inhibitory neurons calculate “subtraction” or “division” to adjust visual sensitivity!
This one has it all – behavior, optogenetics, modeling, cell types, subthreshold mechanisms. Quick thread 🧵below
Lateral inhibition in V1 controls neural and perceptual contrast sensitivity - Nature Neuroscience
The role of lateral inhibition for perception and neural computation remains unsolved. Del Rosario et al. show that distinct types of cortical interneurons in V1 drive lateral inhibition that causes s...
doi.org
haiderlab.bsky.social
This study was a huge collaborative effort led by former grad student Joseph Del Rosario in collab w/ Hannah Choi’s group in the GT Math Dept.
All made possible by *four* #NIH awards (training grants, pathway to independence, and R01s) 🙏
haiderlab.bsky.social
(10/10) We think these circuits could be used to adjust “background” visual signals in highly specific ways and improve visual sensitivity in different environments and conditions (like when one part of the visual field becomes the focus of attention while irrelevant locations become suppressed).
haiderlab.bsky.social
(9/10) Finally, we found SST neurons send long-range axons (> 1mm away!) across the V1 retinotopic map, branching from the site we stimulated to the site we recorded. The anatomy supports the subthreshold and spiking effects of cell-type specific lateral inhibition on perceptual sensitivity.
haiderlab.bsky.social
(8/10) Whole-cell patch-clamp recordings from excitatory neurons in awake mice showed that activating SST lateral inhibition (~1mm away) caused greater hyperpolarization – and this was because of larger synaptic inhibition from SST neurons!
haiderlab.bsky.social
(7/10) The model showed that a higher probability of SST lateral connections was the key factor.

The model predicts that SST lateral inhibition should be stronger than lateral PV inhibition… is this true in V1?