Hanneke Vlaming
@hannekevlaming.bsky.social
260 followers
160 following
10 posts
Assistant Prof at Utrecht University, studying the process of transcription elongation vs early termination. (she/her)
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Reposted by Hanneke Vlaming
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Lucas Farnung
@lucas.farnunglab.com
· Aug 29
IWS1 positions downstream DNA to globally stimulate Pol II elongation - Nature Communications
Although IWS1 has been implicated in transcription-coupled processes, its direct role in RNA polymerase II function remained undefined. Here, the authors demonstrate that IWS1 enhances Pol II elongati...
www.nature.com
Reposted by Hanneke Vlaming
Reposted by Hanneke Vlaming
Reposted by Hanneke Vlaming
Reposted by Hanneke Vlaming
Suyang Zhang
@suyangzhang.bsky.social
· Jul 7
Structural basis of RECQL5-induced RNA polymerase II transcription braking and subsequent reactivation - Nature Structural & Molecular Biology
Using cryo-electron microscopy and biochemistry, Zhang et al. reveal that the DNA helicase RECQL5 and the transcription-coupled DNA repair complex coordinate to regulate transcription elongation rates...
www.nature.com
Reposted by Hanneke Vlaming