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Henry De Belly

@henrydebelly.bsky.social

940 followers 720 following 24 posts

Postdoc in Orion Weiner's lab at UCSF. I work at the interface of Cell Biology and Biophysics. I am into: #Actin, #Membrane, #CellMigration, #Polarity, #Cats, #Mechanobiology #Cheese #CellBiology

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Henry De Belly @henrydebelly.bsky.social · Nov 11

Sharing my latest preprint as a re-introduction to bsky!

biorxiv.org/content/10.1...
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Everyday, cells like this crawl through your body to protect you. While we know that their front 🔴 and back 🔵 polarity programs work together, how exactly do these two processes communicate?

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Mechanobiology Institute @mbisg.bsky.social · 28d

@henrydebelly.bsky.social @oweinerlab.bsky.social elegantly showed how migrating cells exhibit a long-range mutual activation and partitioning of GTPases at both the front and back of the cell, functioning as an integrated mechano-chemical system. He’s also recruiting for his new lab!🧑‍🔬#MBIMPG2025

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Manuel Thery @manuelthery.bsky.social · Jul 8

Ever wished to become an actin star? 😎
Then try getting suspended above a non-adhesive substrate.
www.nature.com/articles/s41...

A multicellular star-shaped actin network underpins epithelial organization and connectivity - Nature Communications

The combined role of cellular junctions and actomyosin networks in tissues remains unclear. Here, the authors identify a tissue-scale star-shaped network of actomyosin that preserves cell shape, limit...

www.nature.com

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Henry De Belly @henrydebelly.bsky.social · Jun 5

Woop woop!!! 🥳

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Semil Choksi @semilc.bsky.social · Jun 5

I'm thrilled to announce that my lab is opening this August in the Department of Cell & Tissue Biology @ UCSF!

We will study airway stem cells and explore how they generate multiciliated cells (my favorite!) to keep pathogens and debris out of the lung. Check out choksilab.org for more!

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Department of Cell and Tissue Biology at UCSF @ctbatucsf.bsky.social · Jun 5

CTB welcomes new Assistant Professor Semil Choksi @semilc.bsky.social to the department! The Choksi Lab will study how airway stem cells generate multiciliated cells - and how this process goes wrong in respiratory disease. His lab is opening this August. Visit choksilab.org to learn more!

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Carsten Schulte @carstenschulte4.bsky.social · May 30

#Science Bluesky, do your thing:
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?

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Gc Rox @gcrox.bsky.social · May 23

All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!

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Kate Cavanaugh @katecavanaugh.bsky.social · May 16

I am a proud HHMI Gilliam Fellow alumn. The HHMI funded me at a critical time in my career - a real inflection point that made me realize that I had a place and future in science. I always looked to the HHMI as a safety net to those historically excluded by academia, 1/4

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Arthur Michaut 🔬🐣 @amichaut.bsky.social · May 12

🚨📣 New preprint alert!
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics

Direct measurements of active forces and material properties unveil the active mechanics of early embryogenesis

Despite progress in probing tissue mechanics, direct long-term measurements in live embryonic epithelia are lacking. This limits our understanding of amniote embryonic morphogenesis, which takes place...

www.biorxiv.org

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Aakriti Jain @aakritijain.bsky.social · Mar 27

SO excited to share that a major part of the postdoctoral work in @robzonculab.bsky.social lab is now published: “Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins” www.science.org/doi/10.1126/...

Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins

Breakdown of every transmembrane protein trafficked to lysosomes requires proteolysis of their hydrophobic helical transmembrane domains. Combining lysosomal proteomics with functional genomic dataset...

www.science.org

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Journal of Cell Biology @jcb.org · Mar 21

In Memoriam: Wolfenson, Giannone, and Schwartz recall the life and many contributions of Michael Sheetz, who passed away on January 30, 2025. rupress.org/jcb/article/...

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Henry De Belly @henrydebelly.bsky.social · Mar 21

This is a huge loss. Michael's work has been extremely influential and inspirational. He was one of my favorite scientist of all time...

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Kaia Mattioli @kaiamattioli.bsky.social · Mar 10

born too late to get a two Western blot Nature paper, born too early to be a science TikTokker, born just in time to start a postdoc during a global pandemic and look for faculty positions during a historic hiring freeze

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Ankita Jha @ankita13jha.bsky.social · Mar 10

As scientist I am going through difficult times (this is understatement of the year for me!!). Past one and half months have been horrible, however I am trying to pick myself up and super excited to share my postdoc work with the community! #cellmigration
www.biorxiv.org/content/10.1...

CD44 and Ezrin restrict EGF receptor mobility to generate a novel spatial arrangement of cytoskeletal signaling modules driving bleb-based migration

Cells under high confinement form highly polarized hydrostatic pressure-driven, stable leader blebs that enable efficient migration in low adhesion, environments. Here we investigated the basis of the...

www.biorxiv.org

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Aakriti Jain @aakritijain.bsky.social · Mar 8

Huge crowds in SF today for #standupforscience. inspiring stories, not only from scientists like @carolynbertozzi.bskyverified.social, but also people who have lived through life-saving/changing experiences as a direct consequence of federally-funded scientific research 💪🏽

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Sandra @lilysch.bsky.social · Mar 5

Added bonus: You would get to live in the South of France!🇫🇷 🍷☀️

🧪

www.404media.co/french-unive...

French University to Fund American Scientists Who Fear Trump Censorship

The program, called ‘safe place for science,’ offers American scientists funding to continue their research in France.

www.404media.co

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Manuel Thery @manuelthery.bsky.social · Mar 5

Unique opportunity to join the CytoMorpho Lab (in Paris ❤️) as a postdoc to work on the self-organization and polarization of reconstituted networks made of microtubules, motors and actin filaments in vitro. Experience required.
Please Repost 🙏 thanks !

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Nicolas Minc @minclab.bsky.social · Jan 3

Our lab has multiple open positions for post-docs to study the regulation and function of cytoplasm mechanics during embryo development.
Details below 👇👇
Please Repost !!!

@ijmonod.bsky.social @cnrs.bsky.social

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Henry De Belly @henrydebelly.bsky.social · Dec 14

The lanyards at ASCB this year are comically loud. It's like everyone is wearing little bells around their necks 🔔.

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Aakriti Jain @aakritijain.bsky.social · Dec 9

Hi! Thought I'd mosey on down to bsky as well with the rest of the science peeps! I love combining old-school biochemistry with all the 'omics' to discover new things about organelle function and cellular metabolism in health and disease.

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Aakriti Jain @aakritijain.bsky.social · Dec 9

Excited for some cool science at #CellBio2024 this year! Come by my poster (Sun. Dec 15, 1.30-3pm Board B136) and stay for my talk (Sun. Dec 15, 4 pm Rm 33B) where I'll tell you about our work on a lysosomal mechanism for membrane protein degradation!

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Xavier Trepat @xaviertrepat.bsky.social · Dec 3

🎈New preprint! We study how single cells move up, down and about fibronectin gradients. Experiments by @icfortunato.bsky.social, theory by David Bruckner. Collaboration with @raimonsunyer.bsky.social and @ehannezo.bsky.social 👇https://biorxiv.org/cgi/content/short/2024.12.02.626413v1

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Henry De Belly @henrydebelly.bsky.social · Nov 21

Congratulations on the beautiful story!!
Motility 🤝 Cytokinesis

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Eszter Posfai @eposfai.bsky.social · Nov 20

Check out our new paper in @currentbiology.bsky.social by amazing grad students @ezlevy.bsky.social and @isabellaleite.bsky.social “A tug-of-war between germ cell motility and intercellular bridges controls germline cyst formation in mice”
authors.elsevier.com/a/1k7fg3QW8S...

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Henry De Belly @henrydebelly.bsky.social · Nov 21

Damn that sucks, I can't imagine the stress... I also don't get it, seems that you can only benefit from doing back to back papers...