Lightnews — Scholar-powered news

Iannacone Lab @iannaconelab.bsky.social · 1d

Our review "From Histology to High-Resolution Mapping: The Rise of Spatial Omics in Immunology" is now online! onlinelibrary.wiley.com/doi/10.1002/...

From Histology to High‐Resolution Mapping: The Rise of Spatial Omics in Immunology

Immune regulation is fundamentally spatial, shaped by tissue architecture and local cues. Spatial omics—transcriptomic, proteomic, metabolomic, lipidomic, and phosphoproteomic platforms—preserve coor...

onlinelibrary.wiley.com

1 3

Reposted by Iannacone Lab

European Journal of Immunology @eurjimmunol.bsky.social · 1d

📣 EJI is proud to share that this year’s Nobel Prize winner, Shimon Sakaguchi, published with us on 6 October: bit.ly/46R7n4g
We extend our heartfelt congratulations to Shimon for receiving the prize in recognition of his pioneering work on Tregs. #NobelPrize #Immunology #Tregs

6 18

Iannacone Lab @iannaconelab.bsky.social · 12d

(2/2) Fun collaboration with @linterman.bsky.social lab. Huge congrats to @cristianbeccaria.bsky.social & @smguillaume.bsky.social for spearheading this! onlinelibrary.wiley.com/doi/10.1111/...

Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers

Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be....

onlinelibrary.wiley.com

Iannacone Lab @iannaconelab.bsky.social · 12d

🧵 (1/2) Interested in tertiary lymphoid structures (TLSs)? Check out our latest review, where we chart how TLSs form across organs and contexts — from lung to liver, CNS, skin, gut & more — and their dual roles in protection vs. pathology.

Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers

Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be....

onlinelibrary.wiley.com

1 2 5

Reposted by Iannacone Lab

Michelle Linterman @linterman.bsky.social · 13d

Great to have this out, and such a pleasure to work together. @smguillaume.bsky.social @cristianbeccaria.bsky.social @iannaconelab.bsky.social

Cristian G Beccaria @cristianbeccaria.bsky.social · 13d

So happy to share that our review in #ImmunolRev is finally out! 😃 We discuss how the immune system builds specialized TLSs across organs and conditions. Huge thanks to @StephanGuillaume, @iannaconelab.bsky.social & @linterman.bsky.social for this collaboration!
dx.doi.org/10.1111/imr.70063

Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers

Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be...

dx.doi.org

6 21

Reposted by Iannacone Lab

Cristian G Beccaria @cristianbeccaria.bsky.social · 13d

So happy to share that our review in #ImmunolRev is finally out! 😃 We discuss how the immune system builds specialized TLSs across organs and conditions. Huge thanks to @StephanGuillaume, @iannaconelab.bsky.social & @linterman.bsky.social for this collaboration!
dx.doi.org/10.1111/imr.70063

Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers

Tertiary lymphoid structures (TLSs) arise in non-lymphoid tissues in response to persistent antigen stimulation and chronic inflammation. Spanning organs from lung and liver to meninges, skin, and be...

dx.doi.org

5 17

Reposted by Iannacone Lab

Fusion Conferences @fusionconf.bsky.social · 28d

Don't forget to secure your place at our new conference!
Cancer Immunology: Across Space & Time
📅Date: 10 Jul - 13 Jul 2026
🌏Location: Lisbon, Portugal
📢Early Bird & Talk Submission: 15th January 2026
Don't miss out, Register now: bit.ly/3IdEwii
#CancerImmuno #FusionImmunology #FusionCancerResearch

2 2 2

Reposted by Iannacone Lab

Valentina Venzin @valentinavenzin.bsky.social · Sep 4

Excited to present at the next OBS immuno seminar our recent work from the @iannaconelab.bsky.social! Happy to make science open for everyone 🌈💜

Open Box Science @openboxscience.bsky.social · Sep 4

OBS Immunology Seminar

👩‍🔬 Verena Van Der Heide,
Icahn School of Medicine at Mount Sinai @cp-immunity.bsky.social
👩‍🔬 @valentinavenzin.bsky.social @iannaconelab.bsky.social @unisr.bsky.social @pasteur.fr

🗓️ Thu, September 4th, 11 AM EDT, 3 pm GMT, 5 pm CET

👇
us02web.zoom.us/meeting/regi...

1 4

Reposted by Iannacone Lab

Valentina Venzin @valentinavenzin.bsky.social · Aug 22

@iannaconelab.bsky.social presenting our work at #IUIS @iuis-online.bsky.social in Vienna highlighting the importance of CD4 T cell mediated help in the liver! 🚀 Thanks @immunologypodcast.com for highlighting our story! @cristianbeccaria.bsky.social podcasts.apple.com/us/podcast/t...

IUIS 2025: Day 3

Podcast Episode · The Immunology Podcast · 08/21/2025 · 25m

podcasts.apple.com

2 7

Reposted by Iannacone Lab

EFIS_Immunology @efis-immunology.bsky.social · Aug 22

🌟Cheers to the #ACTERIA Early Career Awardees! #EFIS is proud to have supported young scientists and hope Vienna inspired you with new connections, and ideas. 🤝Here’s to the next 50 years of advancing science together!💙
@yefis-immunology.bsky.social @eurjimmunol.bsky.social @iannaconelab.bsky.social

4 6

Reposted by Iannacone Lab

Cristian G Beccaria @cristianbeccaria.bsky.social · Aug 21

Thrilled to share some of the stories we've been working on in our @iannaconelab.bsky.social at #IUIS2025 @iuis-online.bsky.social in Vienna! Excited to chat with so many friends and colleagues from around the world! @davidemarotta.bsky.social @CaitlinAAbbott

1 3 14

Reposted by Iannacone Lab

European Journal of Immunology @eurjimmunol.bsky.social · Aug 21

Steffen Jung announced Andreas Radbruch as keynote speaker at #IUIS2025, highlighting his strong support for European Immunology and the importance of backing EJI and European research!

Andreas presenting his newest EJI article by Schneider-Revueltas et al. onlinelibrary.wiley.com/doi/10.1002/...

1 8 9

Reposted by Iannacone Lab

European Journal of Immunology @eurjimmunol.bsky.social · Aug 20

EJI & EFIS are proud to announce the brand-new ECR Article of the Year Award 🏆

Presented by EJI’s Editor-in-Chief Matteo Iannacone at #IUIS2025, this prize celebrates outstanding research by early career researchers published in EJI 🎉

Check the eligibility criteria here👇
bit.ly/3Hvn9t5

1 7 14

Iannacone Lab @iannaconelab.bsky.social · Aug 21

Thanks for sharing @brendaraud.bsky.social and @immunologypodcast.com!

Brenda Raud @brendaraud.bsky.social · Aug 21

I loved seeing the story from @iannaconelab.bsky.social presented live! HBV-infected hepatocytes can prime CD8 cells directly but CD4 help -> Kupffer cells (not DCs) -> CD27 is needed to prevent dysfunction (check episode #109 of @immunologypodcast.com for the full story!)

5

Reposted by Iannacone Lab

European Journal of Immunology @eurjimmunol.bsky.social · Aug 19

📢 Call for papers! Our special issue on Autoimmunity & Environmental Factors is open for submission.

✅Guaranteed peer review for all #IUIS2025 participants!

Contribute to advancing our understanding of how modifiable factors influence immune tolerance and autoimmunity 👉 bit.ly/3HFEgIA

1 3 6

Reposted by Iannacone Lab

yEFIS @yefis-immunology.bsky.social · Aug 18

Editor-in-Chief Nadja Bakocevic presenting at #IUIS2025 Career Fair on the ways @eurjimmunol.bsky.social and @efis-immunology.bsky.social support early career researchers.

✨ Celebrating 50 years of EJI and introducing the brand-new ECR Article of the Year Prize!

2 3 4

Reposted by Iannacone Lab

EFIS_Immunology @efis-immunology.bsky.social · Aug 15

🔬 #EFIS will be at the #IUIS2025 exhibition hall!

Come say hello, discover our programs, network with fellow immunologists, learn about EJI prizes, and grab some treats✨

📅 Aug 17–21 | 📍 Booth # 42

#Immunology

@eurjimmunol.bsky.social @yefis-immunology.bsky.social

1 3 6

Reposted by Iannacone Lab

European Journal of Immunology @eurjimmunol.bsky.social · Aug 18

📢 EJI is at #IUIS2025 in Vienna!
Come meet us at the EFIS booth #42 😃

We’d love to hear about your science, answer your publishing questions, and connect with the global immunology community 🔬🌍

See you there! 👋

@yefis-immunology.bsky.social @efis-immunology.bsky.social @iuis-online.bsky.social

1 8 19

Iannacone Lab @iannaconelab.bsky.social · Aug 14

Do not miss it! 👇

Fusion Conferences @fusionconf.bsky.social · Aug 14

🚨NEW CONFERENCE ALERT! SAVE THE DATE!
Cancer Immunology: Across Space & Time
📅Date: 10 Jul - 13 Jul 2026
🌏Location: Lisbon, Portugal
📢Early Bird & Talk Submission: 15th January 2026
Don't miss out, Register now: bit.ly/4mDdK1f
#CancerImmuno #FusionImmunology #FusionCancerResearch

3

Reposted by Iannacone Lab

Valentina Venzin @valentinavenzin.bsky.social · Aug 1

What can I say... my watercolor made it to the cover of the latest issue of @natimmunol.nature.com, together with our paper on IL-27 in chronic hep B 🚀 We really put the cherry on top in the @iannaconelab.bsky.social @cristianbeccaria.bsky.social. 🥹💜 Check it out! www.nature.com/ni/volumes/2...

2 2 19

Reposted by Iannacone Lab

ACIR @acir-org.bsky.social · Jul 24

Venzin and Beccaria et al. demonstrate that pre-activated CD4+ T cells actively license local hepatic APCs and restore antiviral CD8+ T cell function. bit.ly/4kRAbhS ‪@valentinavenzin.bsky.social‬ @cristianbeccaria.bsky.social‬ ‪@iannaconelab.bsky.social‬

2 5

Reposted by Iannacone Lab

Immunology Podcast @immunologypodcast.com · Jul 24

Drs. @valentinavenzin.bsky.social, @cristianbeccaria.bsky.social, and the @iannaconelab.bsky.social identified the molecular and cellular mechanisms by which CD4⁺ #Tcells can restore antiviral CD8⁺ T cell function in the #liver.

@natimmunol.nature.com: go.nature.com/3Ggjajr
🎧: bit.ly/3GP9NaK

1 3 5

Iannacone Lab @iannaconelab.bsky.social · Jul 22

Thank you @brendaraud.bsky.social and @drsifujg.bsky.social for highlighting our recent @natimmunol.nature.com (25:40) www.immunologypodcast.com/ep-109-phago...

Ep. 109: "Phagocyte Cell Biology" Featuring Dr. Johnathan Canton - The Immunology Podcast

Dr. Johnathan Canton is an Assistant Professor at the University of Calgary, where his lab uses advanced microscopy techniques to study dendritic cells, macrophages, and innate immunity. He talks abou...

www.immunologypodcast.com

1 1 5

Reposted by Iannacone Lab

Valentina Venzin @valentinavenzin.bsky.social · Jul 10

If you’re too busy to read the paper, here’s the Research Briefing in Nature Immunology 🌈 a quick dive into how CD4⁺ T cells and IL-27 revive CD8⁺ T cells right in the liver! @natimmunol.nature.com @iannaconelab.bsky.social www.nature.com/articles/s41...

A liver-centric help circuit revives CD8+ T cells via IL-27 - Nature Immunology

Effector CD4⁺ T cells restore antiviral CD8⁺ T cell function in the liver by licensing Kupffer cells via CD40–CD40L interactions. This triggers IL-27 production and reprograms the hepatic immune envir...

www.nature.com

1 3

Iannacone Lab @iannaconelab.bsky.social · Jul 2

Happy to share our latest review "Targeting HBV with RNA interference: Paths to cure"| Science Translational Medicine www.science.org/doi/10.1126/... written together with @cristianbeccaria.bsky.social, Lena Allweiss, Julie Lucifora, John Tavis, Adam Gehring and Maura Dandri

Targeting HBV with RNA interference: Paths to cure

RNA-targeting therapies hold promise for contributing to HBV cure regimens, but challenges remain before that promise can be realized.

www.science.org

1 9