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Johnston Lab @inchinn.bsky.social · Jul 10

Shreya @shreyac.bsky.social gave an excellent talk at this week's UKSN conference in beautiful Cambridge.

bsky.app/profile/elis...

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Johnston Lab @inchinn.bsky.social · Jul 9

@shreyac.bsky.social

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Elisa Galliano @elisagalliano.bsky.social · Jun 16

Olfaction geeks, come to Cambridge next month for a 30yrs old cross-disciplinary smell chat from philosophy to clinics to circuits 🧠👃
Headliner @dattalab.bsky.social on his lab's brand new olfactory maps study
Networking lunches, fancy College dinner, student discount, plenty of coffee. Go register!

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Tobias Ackels @tobiasackels.bsky.social · May 18

🚨 Preprint alert! 🚨
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.

Spoiler alert: Yes, they can!

Read the paper here: bit.ly/43A9tF9
Short 🧵 below

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Reposted by Johnston Lab

Matt Smear @mattsmear.bsky.social · May 9

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Johnston Lab @inchinn.bsky.social · May 2

Johnston and Filippi lab walk in the Yorkshire Dales

Reposted by Johnston Lab

Joseph D. Zak @josephdzak.bsky.social · Apr 30

Now in its final form, our recent work on how olfactory transduction currents help ensure sparse sensory coding. Led by a post-bac Kai Clane Belonio and a graduate student, Eyerusalem Haile, this was a group effort by the entire laboratory.

www.jneurosci.org/content/45/1...

Amplification of Olfactory Transduction Currents Implements Sparse Stimulus Encoding

Sensory systems must perform the dual and opposing tasks of being sensitive to weak stimuli while also maintaining information content in dense and variable sensory landscapes. This occurs in the olfa...

www.jneurosci.org

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Johnston Lab @inchinn.bsky.social · Apr 25

Beautiful and fascinating work!

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Thomas Bozza @neuroboz.bsky.social · Mar 6

Check out our review comparing typical experimental to naturally-occurring odor concentrations. You might be surprised.
www.jneurosci.org/content/45/1...
Thanks to Matt and Betty for asking me to take part!

Recalibrating Olfactory Neuroscience to the Range of Naturally Occurring Odor Concentrations

Sensory systems enable organisms to detect and respond to environmental signals relevant for their survival and reproduction. A crucial aspect of any sensory signal is its intensity; understanding how...

www.jneurosci.org

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Johnston Lab @inchinn.bsky.social · Feb 28

A new collaborative effort on the impacts of mutations in PDZD8: Autistic features in humans, with mice displaying impaired social recognition behaviour, social odour recognition, and metabolic changes. Well done Dr Pantiru! 🧠 🧪 rdcu.be/ebCH8

Autistic behavior is a common outcome of biallelic disruption of PDZD8 in humans and mice

rdcu.be

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Dinu F Albeanu @dinanthos.bsky.social · Feb 26

New preprint: a simple method (ADePT) for optical control and recording of activity by axially-decoupling the focal planes for widefield patterned photo-stimulation and two photon imaging. Proof-of-principle analysis of functional connectivity in the olfactory bulb. 1/7 #neuroscience

Axially decoupled photo-stimulation and two photon readout (ADePT) for mapping functional connectivity of neural circuits

All optical physiology in vivo provides a conduit for investigating the function of neural circuits in 3-D. Here, we report a new strategy for flexible, axially-decoupled photo-stimulation and two pho...

doi.org

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Catherine Dulac @dulaclab.bsky.social · Feb 26

Our latest findings on social behavior circuits is out: how does the brain responds to social isolation? Terrific work by @dingliu.bsky.social et al. uncovering a circuit with similar neural architecture as physiological needs (hunger, thirst, sleep..). Detailed thread soon.
rdcu.be/ebo63

A hypothalamic circuit underlying the dynamic control of social homeostasis

Nature - New data on brain-wide circuits centred around two interconnected hypothalamic neuron populations provide significant mechanistic insights into the emergence of social need during social...

rdcu.be

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Johnston Lab @inchinn.bsky.social · Feb 10

m.youtube.com/watch?v=oJN6...

Get Data - A "Get Lucky" Science Parody

YouTube video by Neuro Transmissions

m.youtube.com

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Bob Pellegrino @kingfunk.bsky.social · Jan 26

Alexander Fjaeldstad and I have a new chapter in the book Smell, Taste, Eat: The Role of the Chemical Senses in Eating Behaviour, edited by @LorenzoDStafford. Lots of great insights here.

From our chapter, it’s clear that smell loss and its impact on ingestion remain vastly underexplored."

The Effect of Olfactory Disorder (and Other Chemosensory Disorders) on Perception, Acceptance, and Consumption of Food

People with changes in the overall sensory experience of food often complain of taste disturbances, although the problem is normally caused by the loss of aroma in the food (thus an olfactory disorder...

link.springer.com

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Reposted by Johnston Lab

Chris Parr @chrisjparr.bsky.social · Jan 24

Leeds becomes first Russell Group university to quit X but will stay on other platforms like Bluesky. www.researchprofessionalnews.com/rr-news-uk-u...

Leeds becomes first Russell Group university to quit X - Research Professional News

Leeds says Elon Musk’s social media site “no longer aligns with our university values”

www.researchprofessionalnews.com

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Johnston Lab @inchinn.bsky.social · Dec 20

A nice (dendritic) tree for the #FluorescentFriday before Christmas. 🎄

Reconstructed and modeled in elifesciences.org/articles/06250

Retinal ganglion cell filled with a fluorescent dye

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iBehave @ibehave.bsky.social · Nov 12

🔊Major Breakthrough

Researchers from @UniklinikBonn @unibonn.bsky.social @rwth.bsky.social reveal how single neurons respond to smells, images & words!

This study in @natureportfolio.bsky.social bridges the gap between animal & human olfactory research!👃

📖 www.nature.com/articles/s41...

Single-neuron representations of odours in the human brain - Nature

Human piriform and mediotemporal neurons encode odours, and signal how we perceive, rate and identify scents.

www.nature.com

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Johnston Lab @inchinn.bsky.social · Dec 11

We have a fresh new paper!
The PhD project of the talented Mark Conway.

A learning-induced change in the sensitivity of olfactory receptor neurons enables consistent perception of an odor. #olfaction #neuroscience

www.science.org/doi/10.1126/...

Perceptual constancy for an odor is acquired through changes in primary sensory neurons

Learning-induced changes in primary sensory neurons support concentration-invariant perception of an odor.

www.science.org

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Carolina Rezaval @crezaval.bsky.social · Dec 6

New from Shiko Parnas' lab: Classical & operant learning in *Drosophila* rely on distinct neuronal pathways, challenging current paradigms! Unstoppable

www.science.org/doi/10.1126/...

Neuronal circuit mechanisms of competitive interaction between action-based and coincidence learning

Parallel and interfering neuronal circuits are responsible for operant and classical learning.

www.science.org

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Johnston Lab @inchinn.bsky.social · Dec 6

Pretty pericytes,
Perching on a vessel,
Protecting the brain

An old Friday experiment for
#FluorescentFriday #Olfaction #haiku

In vivo 2-photon image of the neurovasculature in the olfactory bulb

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Reposted by Johnston Lab

British Neuroscience Association @britishneuro.bsky.social · Dec 4

✨ We can’t wait to see everyone next week at the 2024 Festive Symposium in Leeds!
It’s your chance to connect with #neuroscientists from academia, clinics, and industry as we explore 'The Resilient Brain'.
Make sure you’ve got your ticket! bna.org.uk/mediacentre/...

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Tim Behrens @behrenstimb.bsky.social · Nov 30

Great blog by Bodo Stern (@hhmi.bsky.social) about the recent Clarivate decision on @elife.bsky.social’s impact factor. www.coalition-s.org/blog/how-the...

How the Web of Science takes a step back

<p>The Web of Science, a major commercial indexing service of scientific journals operated by Clarivate, recently decided to remove eLife from its Science Citation Index Expanded (SCIE). eLife will on...

www.coalition-s.org

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Matt Smear @mattsmear.bsky.social · Nov 22

Sniffing helps animals identify smells and connect them to places and events, but noses can’t sense time or place.

How do brains connect odors with internal models of the world?

Our preprint suggests that the olfactory bulb participates in this connection.

www.biorxiv.org/content/10.1...

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Grubb Lab @grubblabneuro.bsky.social · Nov 29

We have *another* preprint! This work was led by the amazing Candida Tufo, ex-PhD student in the lab.

We show that adult-born dopaminergic cells in the olfactory bulb rapidly functionally resemble their pre-existing counterparts!

Have a look at the preprint here: www.biorxiv.org/content/10.1...

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Johnston Lab @inchinn.bsky.social · Nov 29

Collected by Mark Conway as part of our upcoming paper on perceptual constancy. Mitral and tufted cells in the olfactory bulb expressing GCaMP6 imaged in vivo

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