Jacob K. McPherson
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jacobkmcpherson.bsky.social
Jacob K. McPherson
@jacobkmcpherson.bsky.social
PharmD • PhD Pharmacology • University of Houston
BS Biology • University of Texas at Austin

mcphersonlab.github.io (research lab)
Reposted by Jacob K. McPherson
Nature research paper: Gut micro-organisms associated with health, nutrition and dietary interventions

go.nature.com/4oODWqv
Gut micro-organisms associated with health, nutrition and dietary interventions - Nature
Comprehensive large-scale studies of multi-national populations identified microbiome species consistently associated with favourable and unfavourable health markers, informing future studies of the human gut microbiome and its association with diet and cardiometabolic conditions.
go.nature.com
December 12, 2025 at 9:37 AM
Reposted by Jacob K. McPherson
4·6 billion people lacked essential health services in 2023.

Universal health coverage stands as the organising vision for national health systems. Yet translating this promise into reality has proven complex.

On #UHCDay, read our latest Editorial: spkl.io/63328Aiz6e
December 12, 2025 at 2:33 PM
Reposted by Jacob K. McPherson
Help choose JCB’s cover of the year! Explore 12 breathtaking images submitted by our talented authors and vote for your favorite. Don’t miss your chance to have your say in celebrating the beauty of science. Voting closes on December 31! 👉 www.surveymonkey.com/r/JCB2025Cov...

#ScienceArt
December 12, 2025 at 2:15 PM
Reposted by Jacob K. McPherson
Nature research paper: Gut micro-organisms associated with health, nutrition and dietary interventions

go.nature.com/4a6NYQd
Gut micro-organisms associated with health, nutrition and dietary interventions - Nature
Comprehensive large-scale studies of multi-national populations identified microbiome species consistently associated with favourable and unfavourable health markers, informing future studies of the human gut microbiome and its association with diet and cardiometabolic conditions.
go.nature.com
December 11, 2025 at 1:57 PM
Reposted by Jacob K. McPherson
Our January issue is live! A Focus issue on viral pathogen evolution and global health. The issue explores viral emergence, adaptation, spread, and strategies for surveillance and preparedness to detect and control evolving viral threats.

Read more:
www.nature.com/collections/...
Viral pathogen evolution and global health
Viral pathogen evolution and global health
www.nature.com
December 11, 2025 at 3:24 PM
Reposted by Jacob K. McPherson
A database of 2.75 billion buildings could help scientists to monitor urban planning, climate change, disaster risks and even corruption

go.nature.com/4acdXWm
Giant 3D map shows almost every building in the world
A database of 2.75 billion buildings could help scientists to monitor urban planning, climate change, disaster risks and even corruption.
go.nature.com
December 11, 2025 at 3:50 PM
Reposted by Jacob K. McPherson
Researchers use AI and Reverse Vaccinology 2.0 on human blood samples to identify a potential new mpox target, and use the target in a vaccine that elicited mpox-neutralizing antibodies in mice. #ScienceTranslationalMedicine https://scim.ag/48Huqzj
Antigen-agnostic identification of poxvirus broadly neutralizing antibodies targeting OPG153
Antigen-agnostic isolation of B cells enabled the AI-assisted identification of broadly neutralizing antibodies targeting OPG153.
scim.ag
December 11, 2025 at 4:00 PM
Reposted by Jacob K. McPherson
“We’re at a place now where antibiotic resistance is a global crisis” says Helen Boucher, MD, dean of @tuftsmedschool.bsky.social. When leaders in infectious diseases issue warnings this stark, it’s time to pay attention. Take a closer look at what’s at stake.
Where are we in the battle against antibiotic-resistant infections?
The World Health Organization says that antibiotic resistance rose during the COVID pandemic. But antibiotic stewardship and other efforts are yielding results.
www.aamc.org
December 5, 2025 at 6:53 PM
Reposted by Jacob K. McPherson
For anyone who missed yesterday, our colleague Ed has been doing amazing coverage of the ACIP meeting.
December 5, 2025 at 2:49 PM
Reposted by Jacob K. McPherson
Five of the best science books 📚 These are a few of my favourite sounds

go.nature.com/48U6hH2
These are a few of my favourite sounds: Books in brief
Andrew Robinson reviews five of the best science picks.
go.nature.com
December 5, 2025 at 3:02 PM
Reposted by Jacob K. McPherson
"Not only is there demand for understanding health systems performance but there is also an opportunity to rethink and re-evaluate the assessment itself."

A new Comment introduces the Lancet Commission on Health Systems Performance Assessment: spkl.io/63322A5C6g
December 2, 2025 at 2:33 PM
Reposted by Jacob K. McPherson
Many say that AI tools are saving them time and money, but others have seen the negative effects that such tools can have on research

go.nature.com/4oFomNQ
AI is saving time and money in research — but at what cost?
Artificial intelligence tools are boosting researchers’ productivity, but some worry about the effect of a growing reliance on them.
go.nature.com
December 5, 2025 at 1:10 PM
Reposted by Jacob K. McPherson
Effective Antivirals in Pandemic Preparedness: Past Mistakes, Future Needs

✅ Just Accepted
🔗 https://bit.ly/3KmUhog
December 2, 2025 at 7:43 PM
Reposted by Jacob K. McPherson
📌 Editor’s Choice from this week's issue of #JAMA:

➡️ eGFR Estimate Variability & Clinical Outcomes,
➡️ #Microplastics and Human Health,
➡️ #Hypotension Management During #Surgery, and more.

ja.ma/4eRp9GH
December 2, 2025 at 5:30 PM
Reposted by Jacob K. McPherson
Europe must reform the ways in which science is evaluated. To boost innovation, it must improve research culture, says David Budtz Pedersen

go.nature.com/3Y0652P
Great science happens in great teams — research assessments must try to capture that
Europe must reform the ways in which science is evaluated. To boost innovation, it must improve research culture.
go.nature.com
December 2, 2025 at 2:50 PM
Reposted by Jacob K. McPherson
Science’s 2024 Breakthrough of the Year was lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months.

Learn more about last year's #BOTY on #WorldAIDSDay: https://scim.ag/48pk7zZ
December 1, 2025 at 7:04 PM
Reposted by Jacob K. McPherson
As #AI is increasingly used across all sectors of the economy, our recent webinar explored how workers can learn new skills to adapt to how AI is changing the workplace.

Explore discussions from the webinar on training workers for the #FutureOfWork: https://ow.ly/UzQx50XAi9S
December 1, 2025 at 9:00 PM
Reposted by Jacob K. McPherson
Ampicillin/Sulbactam in Combination with Ceftazidime/Avibactam against Metallo-ß-Lactamase-Producing Carbapenem-Resistant Acinetobacter baumannii: A Genomics-Informed Mechanism-Based Model

✅ Just Accepted
🔗 https://bit.ly/3WUrcmU
December 1, 2025 at 3:10 AM
Reposted by Jacob K. McPherson
Implementation of a bundle for the management of patients with Gram-negative bloodstream infection: a pre-post quasi-experimental study

✅ Just Accepted
🔗 https://bit.ly/47MeDjJ
November 30, 2025 at 10:56 PM
Reposted by Jacob K. McPherson
The advent of AI might be just the latest stage in a guiding biological process that has produced ever more complex, mutually dependent organisms over the history of life

go.nature.com/4onxvKP
What is the future of intelligence? The answer could lie in the story of its evolution
Nature - The advent of artificial intelligence might be just the latest stage in a guiding biological process that has produced ever more complex, mutually dependent organisms over the history of...
go.nature.com
November 30, 2025 at 1:33 PM
Reposted by Jacob K. McPherson
Five years ago, researchers at Google DeepMind unveiled AlphaFold2

go.nature.com/44rM1di
AlphaFold is five years old — these charts show how it revolutionized science
Nature - Since it was unveiled in 2020, Google DeepMind's game-changing AI tool has helped researchers all over the world to predict the 3D structures of hundreds of millions of proteins.
go.nature.com
November 30, 2025 at 2:02 PM
Reposted by Jacob K. McPherson
A possible increase in penicillin-resistant strains of Treponema pallidum

🔗 https://bit.ly/4oQyrbH
November 29, 2025 at 11:55 PM
Reposted by Jacob K. McPherson
“There were some cells in there that were very messed up”

In a technological tour-de-force, researchers have sequenced the whole genomes of more than 100 individual cells from one 74-year-old man
go.nature.com/4rvXH8Y
We are all mosaics: vast genetic diversity found between cells in a single person
Nature - Technical advances allow researchers to trace the genetic changes that occur over time.
go.nature.com
November 29, 2025 at 4:36 PM
Reposted by Jacob K. McPherson
Our latest editorial is now online in advance of our upcoming December issue

Neglected tropical diseases: golden age of elimination?

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #NTD #OpenAccess #OA
November 29, 2025 at 6:10 PM
Reposted by Jacob K. McPherson
With All Good Intentions: How CDC Decisions Harmed Science and People

✅ Just Accepted
🔗 https://bit.ly/4ijTYas
November 29, 2025 at 8:52 PM