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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · 5d

Took them long enough!

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · 26d

😂😂

MwahahahahahadScientist @mads100tist.bsky.social · 27d

DAPI staining is for cowards

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Reposted by Jason Kirk 🔬📷

mesoSPIM: Clear Images. Big samples. Open source. @mesospim.bsky.social · Aug 22

📣We have opened our official User Forum: forum.image.sc/tag/mesospim
In this forum you can connect with 🔬developers and the image analysis experts. Ask your burning questions about the #mesoSPIM hardware, software, and image processing, or help the beginners to get started!
Tip: use project tags!

Topics tagged mesospim

forum.image.sc

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Reposted by Jason Kirk 🔬📷

Andy Moore @aaandmoore.bsky.social · Aug 18

This is an airyscan confocal movie of mitochondria (white) moving around in a mouse astrocyte. Actin filaments are in orange and microtubules are in blue.

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Aug 12

🤩🤩

Society for Developmental Biology @socdevbio.bsky.social · Aug 11

🐣Chick embryo (Gallus gallus domesticus): a window into vertebrate development. From heart and limb formation to neural crest migration and axis patterning, this model has been cracking the developmental code for over a century. Image by Vincent Pasque #ModelMonday #DevBio

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jul 31

JFC...

Jeff Yau 姚明穎 @jeffmyau.bsky.social · Jul 31

www.nature.com/articles/s41...

Respiratory viral infections awaken metastatic breast cancer cells in lungs - Nature

Mouse models show that respiratory infections from viruses such as influenza and SARS-CoV-2 can trigger metastasis of dormant breast cancer cells in the lungs, a finding supported by epidemiological d...

www.nature.com

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Reposted by Jason Kirk 🔬📷

Society for Developmental Biology @socdevbio.bsky.social · Jul 25

🐌💫 Snail embryos never looked so fabulous!
Tubulin (white), phospho-histone H3 (pink), and F-Actin (cyan) light up this early stage like a cytoskeletal disco ball.
Image from Clemens Cabernard & Adam von Barnau Sythoff 🪩🧬 #FluorescenceFriday

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jul 10

This reminds me of keyword stuffing webpages in the late 90’s to improve search engine results. Old dogs - old tricks. 😂

Dr Alessio Veneziano @aveneziano.bsky.social · Jul 10

Hidden prompts in articles to fool #AI reviewers! It'sbrilliant, it's resistance and it's self-defense! It shows the massively wealthy publishing companies that cutting corners is bad for #science! They could use their wealth to pay independent reviewers.... 🧪

www.theregister.com/AMP/2025/07/...

Scholars sneaking phrases into papers to fool AI reviewers

: Using prompt injections to play a Jedi mind trick on LLMs

www.theregister.com

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Reposted by Jason Kirk 🔬📷

Ana Dorrego Rivas @adorrego.bsky.social · Jul 10

A day ahead of #FluorescenceFriday, a (temporal) switch from the bulb to the cortex.

🟣 NeuN
🔵 AnkG

🔬🧠🧪

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jul 9

Just wait for the babies Grandpa. 🥳

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jul 4

🤩🤩🤩

Stacey Ogden 🦔 @labogden.bsky.social · Jul 3

There is beauty in #DevBio. Look at this developing lung. Just look at it. Gorgeous. This early #FluorescenceFriday submission is from postdoc Christina Daly. 🧪 🔬 👩‍🔬 Membrane GFP signal is depth shaded in rainbow. 🌈

Confocal migrograph of a section of a developing lung. Membranes are stained with GFP, which is depth shaded in rainbow.

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jun 28

I’ve been in Venice since Thursday and honestly….what wedding?

Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jun 12

Yeah for files >300Gb we write files to a scratch 4Tb NVMe on the local machine before processing in Imaris. Too many issues with external drive qualities.

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jun 12

Also if you are converting your file with Imaris directly (and not with the separate utility) I would change the default location from the system drive to another available drive.

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jun 12

Where is your converted IMS file stored? Local HDD, network drive? We’ve had janky issues in the past with files stored on network drives especially for large datasets.

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jun 6

It can be - but try this. Keep one channel monochrome (ideally the overall structural label like actin). Having 2 colors is less visually distracting than 3.

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jun 5

Magical lighting Thorben!

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jun 3

Yep - the cutout in the 3D print recesses each magnetic base a fraction of a mm so when the magnets meet the chamber is supported by the full surface area of the print. 😎

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jun 3

New chamber mount design for our @mesospim.bsky.social - magnetic kinematic bases from @thorlabs.bsky.social for the win! 3D printed (for now) bases hold the chamber snugly for precise positioning between experiments. Fill port on the front allows for media addition without disturbing imaging.

Stainless Imaging chamber for mesoSPIM with 3D printed kinematic mounts

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · Jun 3

✊🏻

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · May 26

That is bonkers…

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Reposted by Jason Kirk 🔬📷

Mathieu Preußner @mathpreu.bsky.social · May 16

🔬✨ Today for #FluorescenceFriday:
A close-up of the dorsal part of the first gill arch in a mature zebrafish.
The intricate vascular network supporting respiration, visualized using kdrl:mcherry.

#Zebrafish #DevBio #Microscopy #Fluorescence #SciArt

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · May 7

This is a fantastic idea for the future of cores. Building >>> buying. 👏👏👏

Mir Lab @mirlab.bsky.social · Apr 11

1/n We have an exciting new initiative at UPenn to provide custom advanced microscopy solutions: Advanced Core for Microscope Engineering (ACME): www.med.upenn.edu/cdbacme/ We are looking for a specialist to help run this new facility, job description is attached please help share widely!

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Jason Kirk 🔬📷 @jasonmileskirk.bsky.social · May 6

That might actually be better than a microscope! Have fun!