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Reposted by Jane Coffin Childs Fund for Medical Research

Aaron Whiteley @aaronwhiteley.bsky.social · 6h

Our work on the Panoptes antiphage system is published! Here we find that Panoptes "watches" the cytosol for phage immune evasion proteins–captured in this illustration by Clair Huffine of Insight Illustrations. A beautiful example of the effector triggered immunity paradigm.

Illustration depicting a bacterium under assault by phage. The bacterium “sees” phage immune evasion proteins and protects itself using a newly described antiphage system called Panoptes, named for the many-eyed mythical giant Argus Panoptes. Credit: Clair Huffine Insight Illustrations LLC

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Reposted by Jane Coffin Childs Fund for Medical Research

Seth Blackshaw @sethblackshaw.bsky.social · 1d

Very proud to have Leah working with us.

Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 1d

Leah Elias, Ph.D., is our Featured Fellow! Elias' postdoctoral research in @sethblackshaw.bsky.social's lab is dissecting how the need for restorative sleep is encoded into our brains at the level of cellular circuits and molecular signals. Her findings may reveal novel therapeutic targets ...
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Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 1d

for sleep disorders. See Elias' profile for more information about her exciting research!

www.jccfund.org/fellows/#mod...

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Fellows - Jane Coffin Childs Memorial Fund

Current Fellows

www.jccfund.org

Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 1d

Leah Elias, Ph.D., is our Featured Fellow! Elias' postdoctoral research in @sethblackshaw.bsky.social's lab is dissecting how the need for restorative sleep is encoded into our brains at the level of cellular circuits and molecular signals. Her findings may reveal novel therapeutic targets ...
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Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 6d

Ok, you get the idea. Start getting your application ready, or help us spread the news!

If you have any questions about eligibility, please reach out to our program office!

www.jccfund.org/contact-us/

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Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 6d

- Participate in the awesome annual symposium with JCC Fellows and Scientific Advisors. Recent years were held in NYC and Chicago, and next year is in Seattle. Where will we go next??? Apply and find out!

- Network with JCC alumni who are scientific leaders in academia, industry, and more!

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Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 6d

- For U.S. based labs, postdoc may be citizen of any country.
(Postdocs who are U.S. citizens are also eligible to apply through international labs.)

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Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 6d

Why should you apply for a JCC fellowship??? We're so glad you asked!

- Competitive stipends with extra allowances for research costs, travel to scientific meetings, and for dependents (if applicable)

- Stable funding.

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Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 6d

If you've recently started a postdoc, or are soon to start one in the field of biomedical research (broadly defined), you should apply!

If you know someone who fits this definition - tell them to apply!

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Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 6d

The application portal for the 2026 cycle of Jane Coffin Childs Postdoctoral Fellowships is now live!

We'll be accepting applications through February 2nd, 2026 at 3PM EST.

www.jccfund.org/eligibilty-c...

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To Apply - Jane Coffin Childs Memorial Fund

THE APPLICATION PORTAL IS NOW OPEN. The application will be due February 2, 2026 at 3pm EST. Access the application here. Eligibility Criteria to Apply in 2026 The applicant must meet all eligibility ...

www.jccfund.org

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Reposted by Jane Coffin Childs Fund for Medical Research

Ya'el Courtney, PhD @scienceyael.bsky.social · 7d

Also thankful for fellowship support from @hhmi.org in my PhD and now from @jcchildsfund.bsky.social!

#Neurodevelopment #Psychedelics #ChoroidPlexus #CSF #DevNeuro #Pregnancy #LSD #Preprint

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Reposted by Jane Coffin Childs Fund for Medical Research

Ya'el Courtney, PhD @scienceyael.bsky.social · 7d

TL;DR: Maternal psychedelics reach embryonic CSF within minutes, activate the choroid plexus, alter CSF, and shift cortical development in mice—yielding lasting behavioral changes. A discrete embryonic window is vulnerable via the ChP–CSF axis.

www.biorxiv.org/content/10.1...

Gestational psychedelic exposure disrupts brain development and offspring behavior in mice

Despite increasing non-medical use and clinical investigation of psychedelics, the consequences of prenatal exposure remain unknown. In mice, maternal lysergic acid diethylamide (LSD; 0.3 mg/kg) cross...

www.biorxiv.org

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Reposted by Jane Coffin Childs Fund for Medical Research

Ya'el Courtney, PhD @scienceyael.bsky.social · 7d

🚨 Psychedelics in pregnancy - can a single dose reach the embryo and matter? Yes. In mice they hit embryonic CSF within minutes, activate choroid plexus→CSF axis, & shift cortical development with adult behavioral signatures. @lehtinenlab.bsky.social Preprint:

www.biorxiv.org/content/10.1...

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Gestational psychedelic exposure disrupts brain development and offspring behavior in mice

Despite increasing non-medical use and clinical investigation of psychedelics, the consequences of prenatal exposure remain unknown. In mice, maternal lysergic acid diethylamide (LSD; 0.3 mg/kg) cross...

www.biorxiv.org

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Reposted by Jane Coffin Childs Fund for Medical Research

Kal Tsanov @ktsanov.bsky.social · 13d

Our growing team at @uchicagocancer.bsky.social is building on these concepts, with the goal of translating this knowledge to improved therapies for metastatic cancers. More to come! (4/4)

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Reposted by Jane Coffin Childs Fund for Medical Research

Kal Tsanov @ktsanov.bsky.social · 13d

Huge thanks to everyone who contributed to this team effort #LoweLabMSKCC #LabMassague @danapeer.bsky.social #ChristineIacobuzio #CPCRMSK @ronanchaligne.bsky.social #SAIL #RichardKoche #ERIL, and key funding support from #NCI @jcchildsfund.bsky.social #KatzmanFellowship #GMTEC! (3/4)

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Reposted by Jane Coffin Childs Fund for Medical Research

Kal Tsanov @ktsanov.bsky.social · 13d

🚨Location, location, location! Now out @natcancer.nature.com, the final version of our study showing how a tumor's anatomic site can impact the function of driver gene mutations, using SMAD4 inactivation as in pancreatic cancer as a clinically relevant example: nature.com/articles/s43.... (1/4)

SMAD4 induces opposite effects on metastatic growth from pancreatic tumors depending on the organ of residence - Nature Cancer

Using mouse pancreatic cancer models, Tsanov et al. show that reactivation of SMAD4 at metastatic sites promotes tumor growth in the lung through RUNX1 but restrains metastatic growth through KLF4 in the liver, influenced by organ-specific epigenetic states.

nature.com

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Reposted by Jane Coffin Childs Fund for Medical Research

Amir Levi, Ph.D @amirlevi.bsky.social · 13d

Science of the day: Some spikes are just more positive than others, at least waveform-wise.
Side science: interested in these positive units (Punits), check out this work by Shirly Someck www.nature.com/articles/s42...
#Neuroscience #neuroskyence #punits #PositiveVibes

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Reposted by Jane Coffin Childs Fund for Medical Research

Amir Levi, Ph.D @amirlevi.bsky.social · 16d

Science of the day: the activity of thalamic neuronal population during slow wave sleep. Here, dozens of neurons synchronize their firing activity in a Delta rhythm
Side science: Shana Tova to you all! I hope this year will be a year of science and peace
#Neuroscience #neuroskyence #ShanaTova

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Reposted by Jane Coffin Childs Fund for Medical Research

Amir Levi, Ph.D @amirlevi.bsky.social · 19d

Science of the day: the distance between shanks of this silicone probe, used for electrophysiological recordings from the brain, is 0.125 mm. For scale, a hair at the bottom of the image
Side science: my go to probe is the diagnostic biochips 8 shanks, 128 channels.
#Neuroscience #neuroskyence

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Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 20d

Hu's research @hutchbasicsci.bsky.social may provide insight into how chromosome segregation goes awry leading to aneuploidy and cancer development.

Learn more about Dr. Hu and his fascinating research here:
www.jccfund.org/fellows/curr...
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Current Fellows - Jane Coffin Childs Memorial Fund

Current Fellows

www.jccfund.org

Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 20d

Changkun Hu, PhD, is our featured fellow! Dr. Hu uses in vitro reconstitution and TIRF microscopy (😍😍) to investigate the kinetochore, a protein complex that's required for the proper segregation of chromosomes.
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Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 20d

Our sincerest appreciation goes out to all postdoctoral fellows during National Postdoc Appreciation Week #NPAW2025 - especially to our fabulous JCC Fellows, past and present!

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Jane Coffin Childs Fund for Medical Research @jcchildsfund.bsky.social · 20d

Congrats to Dr. Saintilnord @wesaint.bsky.social on his recently published review on transposable elements in cancer - check it out!

www.cell.com/trends/genet...

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Reposted by Jane Coffin Childs Fund for Medical Research

Albert and Mary Lasker Foundation @laskerfdn.bsky.social · 29d

Joan Steitz was awarded the 2018 Special Achievement #LaskerAward for her pioneering discoveries in RNA biology, and her mentorship & support of #WomeninSTEM. 🧪
laskerfoundation.org/winners/lead...
laskerfoundation.org/joan-steitz-...
Find out who will be recognized on September 11th! #Lasker2025

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Reposted by Jane Coffin Childs Fund for Medical Research

Julia Rogers @juliarurogers.bsky.social · 27d

First time at #MLCB! I'll be speaking tomorrow about my development of an ML predictor of domain–peptide interaction affinity to model proteome-scale signaling networks. It'll be livestreamed too.

Peter Koo @pkoo562.bsky.social · 28d

2025 Machine Learning in Computational Biology (#MLCB) meeting starts TODAY (9/10) at 9:30a (EST) at the NY Genome Center in NYC!

We have a great lineup of keynotes, contributed talks, and posters today and tomorrow

Schedule: mlcb.org/schedule

Join for free via livestream: m.youtube.com/@mlcbconf

MLCB - Schedule

The in-person component will be held at the New York Genome Center, 101 6th Ave, New York, NY 10013. All times below are Eastern Time.

mlcb.org

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