Neural mechanisms underlying flexible learning and decision-making are not fully understood. Using single-cell calcium imaging, authors here found that neurons in orbitofrontal and secondary motor cortex exhibit complementary roles in reward learning, with neurons in the former exerting a sustained role in conditions of uncertainty.

The face reveals more than just emotion. Cazettes, Reato and colleagues show that subtle facial movements reveal hidden cognitive states, reflecting the brain’s ongoing computations and offering a noninvasive window into unexpressed thoughts and decisions.

Inspired by a military strategy to ward off disease-carrying mosquitoes, researchers see if the technique will help cut malaria infections in little ones.

Nine Drosophila researchers share how the connectome transformed the field and what additional new tools they would like to see.

A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...

But the agency has spent nearly its entire budget for this fiscal year, which ends tomorrow.

The authors develop a new computational system for high-throughput mapping of synaptic connectivity using two-photon holographic optogenetics and intracellular recordings.

An experimental gene therapy slowed Huntington’s by up to 75 percent in a small clinical trial. While not a cure, it may give patients longer lives.

Clinical teams across the country are forming a five-year, $37 million consortium to research stillbirth, a long-neglected public health concern. “There’s no question that the ProPublica reporting was...

Judge says district court is proper forum to protest mass grant terminations

Simultaneous recordings were made of hundreds of neurons in the rat frontal cortex and striatum, showing that decision commitment involves a rapid, coordinated transition in dynamical regime and neura...