Jay Noboru (登) Worley
@jnobow.bsky.social
Microbiologist/geneticist/bioinformatician. Free-time musician 🎷
Reposted by Jay Noboru (登) Worley
Just in: The Trump administration sent hundreds of letters Tuesday terminating federal grants supporting mental health and drug addiction services.
Trump administration sends letter wiping out addiction, mental health grants
The Trump administration sent hundreds of letters Tuesday terminating federal grants supporting mental health and drug addiction services.
n.pr
January 14, 2026 at 2:56 PM
Just in: The Trump administration sent hundreds of letters Tuesday terminating federal grants supporting mental health and drug addiction services.
Reposted by Jay Noboru (登) Worley
It has been a long road, but our paper on Klebsiella plasmids is finally out in Lancet Microbe. Thanks to all co authors but especially Marjorie Gibbon and Natacha Couto www.sciencedirect.com/science/arti...
Convergence and global molecular epidemiology of Klebsiella pneumoniae plasmids harbouring the iuc3 virulence locus: a population genomic analysis
Klebsiella pneumoniae is an important pathogen of humans and animals. In the past five years, increasing reports of convergent strains that carry both…
www.sciencedirect.com
January 7, 2026 at 2:13 PM
It has been a long road, but our paper on Klebsiella plasmids is finally out in Lancet Microbe. Thanks to all co authors but especially Marjorie Gibbon and Natacha Couto www.sciencedirect.com/science/arti...
I can't go (multiple reasons), but if you have an interest in Shigella spp. and can, you should! Fine folks.
Happy New Year Shigellophiles! There's only 105 days to go ... don't forget to get your abstract in!
Come and visit me in Paris! #Shigella2026 - travel bursaries deadline tomorrow. Submit your abstracts at www.shigella2026.conferences-pasteur.org/home
January 5, 2026 at 5:18 PM
I can't go (multiple reasons), but if you have an interest in Shigella spp. and can, you should! Fine folks.
Reposted by Jay Noboru (登) Worley
Happy New Year Shigellophiles! There's only 105 days to go ... don't forget to get your abstract in!
Come and visit me in Paris! #Shigella2026 - travel bursaries deadline tomorrow. Submit your abstracts at www.shigella2026.conferences-pasteur.org/home
Come and join us in Paris 2026 to talk all about Shigella!
January 5, 2026 at 5:05 PM
Happy New Year Shigellophiles! There's only 105 days to go ... don't forget to get your abstract in!
Reposted by Jay Noboru (登) Worley
A person with measles visited Boston. We're working with local partners to notify those who may have been exposed to measles. Unvaccinated individuals who have been exposed should contact their health care provider immediately.
Learn more at boston.gov/measles.
Learn more at boston.gov/measles.
www.mass.gov
December 24, 2025 at 3:36 PM
A person with measles visited Boston. We're working with local partners to notify those who may have been exposed to measles. Unvaccinated individuals who have been exposed should contact their health care provider immediately.
Learn more at boston.gov/measles.
Learn more at boston.gov/measles.
Reposted by Jay Noboru (登) Worley
Happy Hollidays to all the DNA Nerds out there.
December 20, 2023 at 2:52 PM
Happy Hollidays to all the DNA Nerds out there.
AAP has a good site for a Hepatitis B vaccine fact check. Just in case you find yourself needing it since there will be confusion today.
www.aap.org/en/news-room...
www.aap.org/en/news-room...
Fact Checked: Hepatitis B Vaccine Given to Newborns Reduces Risk of Chronic Infection
Immunizing newborns against hepatitis B is critical to reduce chronic hepatitis B later in life. False claims that call this benefit into question jeopardize the health of children.
www.aap.org
December 5, 2025 at 4:32 PM
AAP has a good site for a Hepatitis B vaccine fact check. Just in case you find yourself needing it since there will be confusion today.
www.aap.org/en/news-room...
www.aap.org/en/news-room...
Reposted by Jay Noboru (登) Worley
🧪🧪 Nobel laureate Hamilton Smith, who discovered molecular 'scissors' to cut DNA, dies at 94 -- Smith, a microbiologist whose discovery revolutionized the field of genetic engineering, was a Johns Hopkins School of Medicine alumnus and professor emeritus
hub.jhu.edu/2025/11/04/n...
hub.jhu.edu/2025/11/04/n...
Nobel laureate Hamilton Smith, who discovered molecular 'scissors' to cut DNA, dies at 94
Smith, a microbiologist whose discovery revolutionize the field of genetic engineering, was a Johns Hopkins School of Medicine alumnus and professor emeritus
hub.jhu.edu
November 11, 2025 at 7:55 PM
🧪🧪 Nobel laureate Hamilton Smith, who discovered molecular 'scissors' to cut DNA, dies at 94 -- Smith, a microbiologist whose discovery revolutionized the field of genetic engineering, was a Johns Hopkins School of Medicine alumnus and professor emeritus
hub.jhu.edu/2025/11/04/n...
hub.jhu.edu/2025/11/04/n...
Reposted by Jay Noboru (登) Worley
We’re offering free vaccine clinics in Boston. Vaccines are safe, effective, and protect against serious illness. Getting vaccinated keeps you healthy and helps protect your family, friends, and community.
Find upcoming vaccine clinics at boston.gov/vaccine-clinics.
Find upcoming vaccine clinics at boston.gov/vaccine-clinics.
Free Vaccine Clinics in Boston
Everyone ages six months and older is encouraged to get the updated flu and COVID-19 vaccines. Pregnant parents, babies, and older adults should consult their health care professional about RSV vaccin...
boston.gov
October 15, 2025 at 9:09 PM
We’re offering free vaccine clinics in Boston. Vaccines are safe, effective, and protect against serious illness. Getting vaccinated keeps you healthy and helps protect your family, friends, and community.
Find upcoming vaccine clinics at boston.gov/vaccine-clinics.
Find upcoming vaccine clinics at boston.gov/vaccine-clinics.
Reposted by Jay Noboru (登) Worley
NSF today released instructions for the next round of applicants to its Graduate Research Fellowship Program. A key group—second-year Ph.D. students—is no longer eligible, and students who are still able to apply will face an unusually narrow timeframe. https://scim.ag/3KlQkQk
‘Completely shattered.’ Changes to NSF’s graduate student fellowship spur outcry
The announcement comes months later than usual, leaving many would-be applicants stranded
www.science.org
September 26, 2025 at 11:09 PM
NSF today released instructions for the next round of applicants to its Graduate Research Fellowship Program. A key group—second-year Ph.D. students—is no longer eligible, and students who are still able to apply will face an unusually narrow timeframe. https://scim.ag/3KlQkQk
A good reminder to properly source your software!
Heads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change.
Ie: it's not us (Samtools team)! Be warned
Ie: it's not us (Samtools team)! Be warned
September 15, 2025 at 3:52 PM
A good reminder to properly source your software!
Reposted by Jay Noboru (登) Worley
Awesome to see the transparent, systematic, and evidence-based approach behind the WHO Bacterial Priority Pathogens List 2024 out in the Lancet Infectious Diseases www.thelancet.com/journals/lan...
The WHO Bacterial Priority Pathogens List 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance
The 2024 WHO BPPL is a key tool for prioritising research and development investments
and informing global public health policies to combat AMR. Gram-negative bacteria
and rifampicin-resistant M tuber...
www.thelancet.com
August 27, 2025 at 4:13 PM
Awesome to see the transparent, systematic, and evidence-based approach behind the WHO Bacterial Priority Pathogens List 2024 out in the Lancet Infectious Diseases www.thelancet.com/journals/lan...
Reposted by Jay Noboru (登) Worley
New York Times story with profiles of researchers whose grants were terminated.
[Gift Link]
www.nytimes.com/2025/08/24/o...
[Gift Link]
www.nytimes.com/2025/08/24/o...
Opinion | America First? Not When It Comes to Your Health.
www.nytimes.com
August 24, 2025 at 1:08 PM
New York Times story with profiles of researchers whose grants were terminated.
[Gift Link]
www.nytimes.com/2025/08/24/o...
[Gift Link]
www.nytimes.com/2025/08/24/o...
Reposted by Jay Noboru (登) Worley
Thrilled that our paper is in print @science.org!!
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
August 15, 2025 at 5:37 AM
Thrilled that our paper is in print @science.org!!
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
Reposted by Jay Noboru (登) Worley
Science’s place in society is being renegotiated, as researchers navigate political polarization, shifting federal priorities, and public skepticism. Many of us feel a growing responsibility to engage beyond the lab but don’t always know where to start or how to break through youtu.be/pzYt8up4CoU
Empowering Change with Civic Science
YouTube video by American Society for Microbiology
youtu.be
August 14, 2025 at 8:20 PM
Science’s place in society is being renegotiated, as researchers navigate political polarization, shifting federal priorities, and public skepticism. Many of us feel a growing responsibility to engage beyond the lab but don’t always know where to start or how to break through youtu.be/pzYt8up4CoU
Reposted by Jay Noboru (登) Worley
Requiring grant review by political appointees will continue to delay and disrupt critical research and interferes with scientists’ ability to help protect the nation’s health and security. Read our statement: asm.org/press-releas...
ASM Responds to Improving Oversight of Federal Grantmaking
ASM calls on the Trump Administration to put science ahead of politics and immediately end its plan to force scientific grants to be reviewed by political appointees.
asm.org
August 8, 2025 at 7:55 PM
Requiring grant review by political appointees will continue to delay and disrupt critical research and interferes with scientists’ ability to help protect the nation’s health and security. Read our statement: asm.org/press-releas...
Reposted by Jay Noboru (登) Worley
Here's our new broad review on the extended mobility of plasmids, about all mechanisms driving and limiting their transfer. From conjugation to conduction, phage-plasmids to hitchers, molecular to evolutionary dynamics, ecology to biotech. The state of affairs. 1/9 academic.oup.com/nar/article/...
July 23, 2025 at 7:35 AM
Here's our new broad review on the extended mobility of plasmids, about all mechanisms driving and limiting their transfer. From conjugation to conduction, phage-plasmids to hitchers, molecular to evolutionary dynamics, ecology to biotech. The state of affairs. 1/9 academic.oup.com/nar/article/...
Really nice study that gives me more than a bit to think about - the idea that a probiotic cocktail to prevent C. difficile recurrence might involve strains that colonize transiently and that promote the desired species composition is noteworthy IMO.
New paper is out from our lab showing that some probiotics can accelerate and prolong the return of colonization resistance to C. difficile after antibiotics.
news.ncsu.edu/2025/07/prob...
news.ncsu.edu/2025/07/prob...
Probiotics Can Help or Hinder Gut Recovery After Antibiotic Treatment
news.ncsu.edu
July 21, 2025 at 6:32 PM
Really nice study that gives me more than a bit to think about - the idea that a probiotic cocktail to prevent C. difficile recurrence might involve strains that colonize transiently and that promote the desired species composition is noteworthy IMO.
Reposted by Jay Noboru (登) Worley
A new bionic prosthesis that directly links to the body’s muscles and nerves enables above-knee amputees to move with greater agility, precision, and sensory awareness than traditional devices, researchers report in Science. scim.ag/40YTleG
July 16, 2025 at 6:57 PM
A new bionic prosthesis that directly links to the body’s muscles and nerves enables above-knee amputees to move with greater agility, precision, and sensory awareness than traditional devices, researchers report in Science. scim.ag/40YTleG
Reposted by Jay Noboru (登) Worley
![Comic. [block quote] “Far better an approximate answer to the *right* question, which is often vague, than an *exact* answer to the wrong question, which can always be made precise.” -John W. Tukey, The Future of Data Analysis (1962) [caption] Happy Approximate Birthday to John Tukey, author of my favorite statistics quote, who was born 110.000 years ago sometime this week.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cz73r7iyiqn26upot4jtjdhk/bafkreid4vie3df7ltmh7capumhhqcpbejyr7ya7y762fasdeq46ud3gyva@jpeg)
Reposted by Jay Noboru (登) Worley
U.S. drug deaths dropped by roughly 40% last year among people under the age of 35. It's a welcome pivot for families and communities devastated by fentanyl.
Drug deaths plummet among young Americans as fentanyl carnage eases
U.S. drug deaths dropped by roughly 40% last year among people under the age of 35. It's a welcome pivot for families and communities devastated by fentanyl.
n.pr
June 10, 2025 at 1:53 PM
U.S. drug deaths dropped by roughly 40% last year among people under the age of 35. It's a welcome pivot for families and communities devastated by fentanyl.
Reposted by Jay Noboru (登) Worley
Reposted by Jay Noboru (登) Worley
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.
May 22, 2025 at 12:42 PM
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.
Reposted by Jay Noboru (登) Worley
200+ scientists are in the middle of a marathon livestream to show why weather and climate science is so important and needs all our help to continue.
It is here: wclivestream.com/watch
It is here: wclivestream.com/watch
Redirecting to: https://www.youtube.com/@wclivestream/live
wclivestream.com
May 28, 2025 at 11:03 PM
200+ scientists are in the middle of a marathon livestream to show why weather and climate science is so important and needs all our help to continue.
It is here: wclivestream.com/watch
It is here: wclivestream.com/watch