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Aaron Whiteley @aaronwhiteley.bsky.social · 22h

Our work on the Panoptes antiphage system is published! Here we find that Panoptes "watches" the cytosol for phage immune evasion proteins–captured in this illustration by Clair Huffine of Insight Illustrations. A beautiful example of the effector triggered immunity paradigm.

Illustration depicting a bacterium under assault by phage. The bacterium “sees” phage immune evasion proteins and protects itself using a newly described antiphage system called Panoptes, named for the many-eyed mythical giant Argus Panoptes. Credit: Clair Huffine Insight Illustrations LLC

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Heran Darwin, PhD @heran.bsky.social · 1d

We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

apply.interfolio.com

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Jonathan Pruneda @jnpruneda.bsky.social · 2d

Ha! I love that idea :)

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Irina Bezsonova @irinabezsonova.bsky.social · 3d

This October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social

Day 5
Prompt DEER
Pdb 4YXH

Two molecules of a deer prion protein decorate its head. Misfolded prions can make other prions to misfold causing neurodegenerative diseases in mammals.

Next: PIERCE
Suggestions?

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Shabaana Khader @khadershabaana.bsky.social · 3d

Dear #microbiology and #immunology community- I took a break from social media after I deleted my Twitter account, but am back here. Please help me rebuild my community by following me and amplifying this message- I will follow you back. Thank you and I look forward to our many interactions!

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Shabaana Khader @khadershabaana.bsky.social · 3d

UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

apply.interfolio.com

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Jonathan Pruneda @jnpruneda.bsky.social · 3d

Haha, well you know my bias, but branched ubiquitin chains look similar to deer antlers…

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Irina Bezsonova @irinabezsonova.bsky.social · 5d

This October I’m drawing one molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social

Day 3/31
Prompt CROWN

Coronavirus spike protein. The crown sits on one of its three receptor-binding domains - a key element for successful infection.

Pdb: 6ZWV

Next prompt is MURKY and I’m at loss

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Jonathan Pruneda @jnpruneda.bsky.social · 3d

Amazing! I love how you tackled this one. I thought I gave you quite the challenge with that suggestion ;)

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Jonathan Pruneda @jnpruneda.bsky.social · 6d

I’m sure it’s too large, but spike proteins give coronaviruses their “crown” shape.

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ThePatrick&WatsonLabs @thepwlab.bsky.social · 6d

If you are somehow still compelled to be a PI in the world in which we find ourselves, we'd love to have you as a colleague!

Two positions in Biochemistry at Vanderbilt University.

www.nature.com/naturecareer...

www.nature.com/naturecareer...

Assistant Professor of Biochemistry at Vanderbilt University - Nashville, Tennessee job with Vanderbilt University School of Medicine | 12843515

Department of Biochemistry, School of Medicine—Basic Sciences

www.nature.com

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Jonathan Pruneda @jnpruneda.bsky.social · 7d

Good one!

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Irina Bezsonova @irinabezsonova.bsky.social · 7d

This October I’m drawing one molecule a day inspired by proteins @rcsb.bsky.social

Day 1/31
Prompt MUSTACHE
Pdb 2QZI

Let’s start with something fun:
Mr. Potato head’s ‘stache is made of Androgen Receptor that binds testosterone and helps maintain his male phenotype

Next prompt: WEAVE
suggestions?

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Philipp Dexheimer @philippdexheimer.bsky.social · 7d

🧬 🎨 ⛰️ Hey y'all, the second online 𝐒𝐂𝐈𝐄𝐍𝐂𝐄 𝐀𝐑𝐓 𝐒𝐔𝐌𝐌𝐈𝐓 is about to go down tomorrow on Thursday from 16:00 - 18:00 (CET)

We have an absolutely exquisite line up - sign up at www.scienceartsummit.com & spread the word to your network, it's free!

Reposts appreciated, see y'all tomorrow!

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Lucas Farnung @lucas.farnunglab.com · 9d

New week, new tool: Find our Protein Domain Designer tool to generate publication-ready protein domain diagrams here: domaindesigner.farnunglab.com

Protein Domain Designer tool for the generation of publication-ready protein domain diagrams

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Avinash Shenoy @avishenoy.bsky.social · 10d

📢A new effector-triggered immunity role for GBP1! No place for pathogens to hide now that GBP1 can detect extracellular pathogens that hijack the actin cytoskeleton. Surprise*suprise* GBP1 does this independently of LPS! 🧵
biorxiv.org/content/10.1...

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Irina Bezsonova @irinabezsonova.bsky.social · 12d

It’s almost October!
I plant to participate in inktober challenge again this year. One protein drawing a day for 31 days. I would LOVE your suggestions!
Check out the prompt list and nominate a pdb of a protein for me to draw that could be a good fit for any of these prompts.
Wish me luck!

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Lori Passmore @lapassmore.bsky.social · 11d

We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM.

Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩
#RNA #cryoEM

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Institute for Protein Innovation @ipiproteins.bsky.social · 15d

Frequent user of epitope tags? Try ours!

IPI epitope tag antibodies & plasmids are now available through our partner @addgene.bsky.social!

buff.ly/YEuZDIp

Epitope tag antibody collection

Epitope tags are short amino acid sequences fused to a protein’s N- or C-terminus. When paired with an antibody that specifically recognizes this sequence, epit

buff.ly

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Jonathan Pruneda @jnpruneda.bsky.social · 19d

Maybe both! We’re excited to find out.

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dimitristypas.bsky.social @dimitristypas.bsky.social · 22d

The September @natsmb.nature.com issue is out! www.nature.com/articles/s41...
We feature very interesting papers on ubiquitylation and degradation. Really excited to continue to serve the proteostasis and PTMs communities and publish conceptually insightful work.

Focus on ubiquitylation and protein degradation - Nature Structural & Molecular Biology

We highlight primary research and commissioned content that delve into the biology of ubiquitylation and degradation mechanisms.

www.nature.com

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Kate Baker @ksbakes.bsky.social · 21d

Come and join us at @shigellameeting.bsky.social in Paris 2026. Registrations are now open! www.shigella2026.conferences-pasteur.org/home and follow the Shigella starter pack go.bsky.app/6Vbwhjc (message to be added)! 215 days to go!

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mansoorlabohsu.bsky.social @mansoorlabohsu.bsky.social · 23d

Another manuscript from our group this week with the first structures of the human P2X7 receptor facilitating development of a novel scaffold for P2X7R antagonists:

urldefense.com/v3/__https:/...

@pacificnwcryoem.bsky.social
@ohsunews.bsky.social
@ohsubrain.bsky.social

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Rune Busk Damgaard @rbdamgaard.bsky.social · 23d

A few months ago, our review “The Molecular Toolbox for Linkage Type-Specific Analysis of Ubiquitin Signaling” 🧬🧰🛠️ came out in ChemBioChem. Time to give it a spotlight!

chemistry-europe.onlinelibrary.wiley.com/doi/full/10....

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Kimberly Beatty @beattylab.bsky.social · 23d

Last chance for early registration for the 2025 Chemical Biology & Physiology Symposium (Dec. 11-13 in Portland, Oregon, USA). Register here:
www.ohsu.edu/school-of-me...
Great program, including talks by Carasco, Chang, Bogyo, Baskin, Swarts, Sampson, Sletten, Dodani, Francis, Urano, Gibbs, etc.

Chemical Biology and Physiology 2025 | OHSU

Chemical Biology and Physiology Conference 2025, December 11-13, 2025

www.ohsu.edu

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