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Reposted by Jorge Almagro

Elaine Fuchs Lab @thefuchslab.bsky.social · Jun 17

Yearly Fuchs lab picnic 🧺

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Reposted by Jorge Almagro

Elaine Fuchs Lab @thefuchslab.bsky.social · Jun 12

New paper alert! We report in @cp-cellmetabolism.bsky.social how serine regulates stem cell fate in physiology and upon wounding.
Good work, Jesse and collabs!
www.cell.com/cell-metabol...

The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury

Novak et al. discover that dietary serine impacts whether hair follicle stem cells (HFSCs) prioritize hair growth or skin repair after injury. HFSCs gauge metabolic stress using the ISR and accelerate...

www.cell.com

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Reposted by Jorge Almagro

EL PAÍS @elpais.com · Jun 11

Dos decenas de sociedades científicas han solicitado a la Comunidad de Madrid que impida urgentemente el “riesgo de destrucción” del Museo Olavide, una joya de la historia de la medicina que incluye unas 700 figuras de cera de pacientes reales

Decenas de sociedades científicas piden a la Comunidad de Madrid que impida la destrucción del Museo Olavide

Las instituciones recuerdan al Gobierno de Isabel Díaz Ayuso que la colección, una joya de la medicina expulsada por la Universidad Complutense, pertenece a una consejería. EL PAÍS graba los preparativos del traslado

elpais.com

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Jorge Almagro @jorgealmagro.bsky.social · Apr 9

It was heartwarming to join academic workers together in the fight against funding cuts, layoffs, and attacks to freedom of speech in our campuses. Scientists will not give up! @uaw.org

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Jorge Almagro @jorgealmagro.bsky.social · Mar 25

“…España, para cuyos ciudadanos la prioridad máxima debe ser la educación e investigación (40%, frente al 23% de media europea), mientras que la defensa cae al 20%”
elpais.com/internaciona...

Los españoles son los europeos menos preocupados por la seguridad y defensa, según el Eurobarómetro

La última encuesta de la UE subraya la importancia de mostrar “unidad” ante los desafíos globales

elpais.com

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Jorge Almagro @jorgealmagro.bsky.social · Mar 23

Submitting my PhD paper after 7.5 years 🫣

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Kevin Ng @kevinng.bsky.social · Mar 4

My thoughts on Heggie’s Moby-Dick at the Met, for @thetimes.com

www.thetimes.com/culture/clas...

Moby-Dick review — the Met sets sail with Jake Heggie’s sprawling epic

The opera — newly staged in its Metropolitan Opera premiere — is as ambitious and frustrating as its source material

www.thetimes.com

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Jorge Almagro @jorgealmagro.bsky.social · Mar 1

Postdocs vs students @thefuchslab.bsky.social laser tag was barely a competition 😏

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Jorge Almagro @jorgealmagro.bsky.social · Feb 20

Yesterday we marched to oppose the hijacking of the NIH and the government by a nazi oligarch. Hands off the NIH!! No research, no cures ✊🏼

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Elaine Fuchs Lab @thefuchslab.bsky.social · Feb 11

Great news! @greatysp.bsky.social @jorgealmagro.bsky.social

Nature Reviews Cancer @natrevcancer.nature.com · Feb 11

🥳 Our 4th most downloaded article in 2024:

Beyond genetics: driving cancer with the tumour microenvironment behind the wheel by @thefuchslab.bsky.social & colleagues

https://bit.ly/42Cvr...

@rockefelleruniv.bsky.social @hhmi.bsky.social @natureportfolio.bsky.social #NRCtop10of2024

Beyond genetics: driving cancer with the tumour microenvironment behind the wheel - Nature Reviews Cancer

In their Review article, Fuchs and colleagues discuss how a single or a few mutations in adult cells can lead to invasive cancers without a high mutational burden, demonstrating that non-genetic factors induce the epigenetic changes necessary for tumorigenesis.

bit.ly

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Reposted by Jorge Almagro

Leo Yuan @greatysp.bsky.social · Feb 11

Congratulations to @jorgealmagro.bsky.social and @thefuchslab.bsky.social as well!! 🎊🎉🥳🥳 @rockefelleruniv.bsky.social @hhmi.bsky.social

Nature Reviews Cancer @natrevcancer.nature.com · Feb 11

🥳 Our 4th most downloaded article in 2024:

Beyond genetics: driving cancer with the tumour microenvironment behind the wheel by @thefuchslab.bsky.social & colleagues

https://bit.ly/42Cvr...

@rockefelleruniv.bsky.social @hhmi.bsky.social @natureportfolio.bsky.social #NRCtop10of2024

Beyond genetics: driving cancer with the tumour microenvironment behind the wheel - Nature Reviews Cancer

In their Review article, Fuchs and colleagues discuss how a single or a few mutations in adult cells can lead to invasive cancers without a high mutational burden, demonstrating that non-genetic factors induce the epigenetic changes necessary for tumorigenesis.

bit.ly

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Reposted by Jorge Almagro

Nature Reviews Molecular Cell Biology @natrevmcb.nature.com · Feb 5

New #Review! 🥳

@jorgealmagro.bsky.social, @thefuchslab.bsky.social et al. discuss the role of stem cell mechanics during developmental processes and what happens when the mechanics of the stem cell niche are disrupted in cancer.

👉 go.nature.com/3EsJzJx

#StemCells #Mechanobiology #Cancer

Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology

Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...

go.nature.com

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Reposted by Jorge Almagro

Nature Reviews Molecular Cell Biology @natrevmcb.nature.com · Jan 29

Shaping epithelial tissues by stem cell mechanics in development and cancer

Nature Reviews Molecular Cell Biology, Published online: 29 January 2025; doi:10.1038/s41580-024-00821-0Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of…

bit.ly

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Jorge Almagro @jorgealmagro.bsky.social · Jan 29

Very happy to see our review out in @natrevmcb.bsky.social!
Here we discuss how stem cells exert forces to sculpt tissues in development and homeostasis, and how stem cell mechanics go awry upon malignant transformation. Read it here 👇
www.nature.com/articles/s41...

Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology

Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...

www.nature.com

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Reposted by Jorge Almagro

Elaine Fuchs Lab @thefuchslab.bsky.social · Jan 29

Our first 2025 paper!
We discuss in @natrevmcb.bsky.social how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @jorgealmagro.bsky.social 👏
www.nature.com/articles/s41...

Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology

Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...

www.nature.com

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Jorge Almagro @jorgealmagro.bsky.social · Jan 16

Paper of the Week! Norepinephrine oscillation during sleep regulates blood/CSF flow and waste clearance
With @kevinng.bsky.social @fesubtil.bsky.social @rysazaman.bsky.social
www.cell.com/cell/abstrac...

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Jorge Almagro @jorgealmagro.bsky.social · Jan 15

What an exciting read 😍

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Reposted by Jorge Almagro

Tim Stearns @stearnslab.bsky.social · Jan 13

Caltech has set up a disaster relief fund for Caltech and Jet Propulsion Lab community members affected by the fires. Many lived in Altadena, which has been very heavily damaged. Please consider giving.
giving.caltech.edu/areas-to-sup...

The Caltech and JPL Disaster Relief Fund

giving.caltech.edu

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Jorge Almagro @jorgealmagro.bsky.social · Jan 10

Reading a textbook may give answers to such essential questions 😅
From Kandel et al. “Principles of Neural Science” (5th edition, before Piezo was identified as the master mechanosensor)

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Reposted by Jorge Almagro

Vienna BioCenter Scientific Training @vbcscitraining.bsky.social · Jan 10

The Vienna BioCenter Summer School 2025 call is now open for applications from talented undergrads. It is the perfect preparation for students who are interested in graduate study in the life sciences arena. 9-week research project, accommodation and stipend for successful candidates.

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Jorge Almagro @jorgealmagro.bsky.social · Jan 9

Kicking off 2025 Paper of the Week with @kevinng.bsky.social & @fesubtil.bsky.social. Today we discussed our friend @martinaparigi.bsky.social et al. recent paper in @nature.com. How do epithelia unlink necessary drivers of regeneration from malignant transformation?
www.nature.com/articles/s41...

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Jorge Almagro @jorgealmagro.bsky.social · Jan 8

Congratulations Jimmy and @paigearnold.bsky.social 👏🏼

The Rockefeller University @rockefeller.edu · Jan 8

Thrilled to announce that two Rockefeller scientists have been named @hhmi.bsky.social Hanna Gray Fellows!

Congratulations to @paigearnold.bsky.social of the
Marraffini lab and Jim Castellanos of @thefuchslab.bsky.social and Weill Cornell Medicine on their awards!

HHMI Names the 2024 Hanna Gray Fellows | HHMI

The cohort includes early career scientists working in research areas ranging from treatment-resistant cancers to how animals evolved to live on land. The HHMI Hanna H. Gray Fellows Program provides e...

www.hhmi.org

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Jorge Almagro @jorgealmagro.bsky.social · Jan 2

Birding (and lynxing🤞🏼) with @atalavera.bsky.social somewhere in La Mancha…

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Kevin Ng @kevinng.bsky.social · Jan 1

My first review of 2025 - Michael Mayer’s new Aida at the Met, for @thetimes.com

www.thetimes.com/culture/clas...

Aida review — the Met’s tacky show is like a night in a Luxor casino

Angel Blue’s impassioned singing as the heroine of Verdi’s opera is the highlight of a dispiriting night at the Metropolitan Opera in New York

www.thetimes.com

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Reposted by Jorge Almagro

Elaine Fuchs Lab @thefuchslab.bsky.social · Dec 31

Cancers may arise in tissues with a low mutational burden. It’s up to the microenvironment! We discussed this in @natrevcancer.bsky.social
www.nature.com/articles/s41...

Beyond genetics: driving cancer with the tumour microenvironment behind the wheel - Nature Reviews Cancer

In their Review article, Fuchs and colleagues discuss how a single or a few mutations in adult cells can lead to invasive cancers without a high mutational burden, demonstrating that non-genetic ...

www.nature.com

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