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Josh Currie

@joshcurrie.bsky.social

2.8K followers 3.5K following 310 posts

Studying principles of tissue regeneration in the axolotl and looking toward regenerative therapies. Asst. Professor at Wake Forest University. Views my own. He/him. https://www.currie-regenerationlab.com/

www.currie-regenerationlab.com

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Josh Currie @joshcurrie.bsky.social · Nov 11

As a re-introduction to new followers, my lab at Wake Forest University studies mechanisms of regeneration in the phenomenal #axolotl with an emphasis on imaging. We think that visualizing cells and molecules in 3D/4D is vital to understanding how regeneration works!
currie-regenerationlab.com

Cells in the regenerating axolotl, labeled with a multi-colored fluorescent reporter, "Limbow"

The highly regenerative Mexican axolotl (Ambystoma mexicanum)

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Josh Currie @joshcurrie.bsky.social · 5h

Sad to hear about John Gurdon. In my dev bio class we, of course, talk about his foundational discoveries, but we also talk about the random serendipity that elevated a few model species into the limelight. We read this great piece by Gurdon on the history of Xenopus

The introduction of Xenopus laevis into developmental biology: of empire, pregnancy testing and ribosomal genes - PubMed

The introduction of Xenopus laevis into developmental biology: of empire, pregnancy testing and ribosomal genes

pubmed.ncbi.nlm.nih.gov

Reposted by Josh Currie

The New York Times @nytimes.com · 1d

Fred Ramsdell was parked at a campground in Montana on Monday when his wife suddenly started shouting. He first thought that maybe she had seen a grizzly bear. Instead, she had regained cell service and had seen a flood of text messages with the same news. “You just won the Nobel Prize!” she yelled.

Winning a Nobel Prize Interrupted His Off-the-Grid Vacation

Fred Ramsdell found out about his Nobel Prize nearly 12 hours after it was announced because he was on vacation in the Rockies.

nyti.ms

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Reposted by Josh Currie

Our World in Data @ourworldindata.org · 1d

Does the news reflect what we die from?

The image presents a comparison of the leading causes of death in the United States for 2023 and the media coverage these causes receive from three news outlets: The New York Times, The Washington Post, and Fox News.

In the footer, it notes the data sources, indicating that the information is based on media mentions from Media Cloud (2025) and death data from the US CDC (2025) and the Global Terrorism Index, with a clarification that values are normalized to sum to 100%.

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Reposted by Josh Currie

Oded Rechavi @odedrechavi.bsky.social · 1d

Fwd: Fwd: “I hope this email finds you well”

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Josh Currie @joshcurrie.bsky.social · 2d

"By 'the deal,' I do not mean ....a contract by which both sides are equally bound. Instead I mean a 'deal' in the special Donald Trump sense: an agreement you and I sign that binds you to do what I want, grants me new leverage over you to demand more in the future, and does very little to bind me."

Balkinization: The Art of Replacing the Law with the Deal

A group blog on constitutional law, theory, and politics

balkin.blogspot.com

Reposted by Josh Currie

Joey Fishkin @fishkin.bsky.social · 4d

The question journalists need to be asking is: WHY is the government trying this?

It’s because they want to control universities in unlawful ways that courts will not allow; it’s not working; so they’re trying to get universities to sign up “voluntarily” for unlawful levels of government control.

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darren32359.bsky.social @darren32359.bsky.social · 3d

tennesseelookout.com/2025/10/02/e...

EV battery component company backs out of plans for $152M Haywood County facility • Tennessee Lookout

A South Korean battery component maker has backed out of plans to build a $152.5 million electrolyte manufacturing facility to Haywood County.

tennesseelookout.com

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Reposted by Josh Currie

Awful Announcing @awfulannouncing.bsky.social · 4d

ESPN shares an interview with a UNC student going into commercial, with Clemson leading 28-3.

"TCU was... I went to that game. And that was, that was one of the saddest feelings I've had in University so far. I've failed midterms before, so that's saying something." 🏈💀 #CFB

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Reposted by Josh Currie

Lori O'Brien @llobrienlab.bsky.social · 4d

Sharing this excellent review now out from postdoc Sarah McLarnon! Lots of useful info on 3D imaging, quantification of imaging data, and how this has been applied to the kidney. And since it's #FluorescenceFriday, sharing a figure with our own imaging data!
www.sciencedirect.com/science/arti...

Figure from our review paper showing various fluorescence microscopy images of cells and structures of the kidney

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Reposted by Josh Currie

The Company of Biologists @biologists.bsky.social · 5d

Our next extraordinary biologist is Mark Peifer, recent @biologists.bsky.social Director and a prolific author, having published in @dev-journal.bsky.social, @jcellsci.bsky.social and @biologyopen.bsky.social. #100biologists
@peiferlabunc.bsky.social

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Reposted by Josh Currie

Drug Monkey @drugmonkey.bsky.social · 6d

yep. You can't make a 'better case' that convinces tyranny of the value of science since knowledge is tyranny's kryptonite.

Science Vs @sciencevs.bsky.social · 7d

This moment from our latest episode with science writer @edyong209.bsky.social is 🔥

We asked Ed — how do we talk up the benefits of science in the face of government cuts? He told us that's the wrong approach. 🧪

Listen wherever, or watch on Spotify 👇

open.spotify.com/episode/7Evh...

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Reposted by Josh Currie

Jennifer N. Victor @jenvictor.bsky.social · 7d

BBC interviewer: Is there a fundamental flaw in American politics?

Me: Absolutely. The US is operating political parties software on institutional hardware that assumes parties don't exist because checks and balances will prevent tyranny. That turns out to be wrong.
www.bbc.co.uk/programmes/w...

BBC World Service - Newsday, US government shutdown

A final vote on extending government spending has failed to pass the US Senate.

www.bbc.co.uk

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Reposted by Josh Currie

Ryan Marino, MD @ryanmarino.bsky.social · 7d

This is why we fund scientists to study things like oyster slobber even if you don’t think it sounds important

Leah McElrath @leahmcelrath.bsky.social · 9d

⚠️ Chinese researchers have invented bone glue that mimics how oysters stick to surfaces underwater.

The adhesive can reportedly repair orthopedic fractures in 2-3 minutes, even in blood-rich environments, and is bioabsorbable.

interestingengineering.com/science/chin...

China's oyster-inspired 'bone glue' bonds fractures in minutes

A new oyster-inspired Bone-02 adhesive can revolutionize bone repair without metal fasteners.

interestingengineering.com

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Reposted by Josh Currie

Joachim Goedhart @joachimgoedhart.bsky.social · 8d

Identification of optimal fluorophores for use in the Drosophila embryo by Timothy E Saunders and team: www.biorxiv.org/content/10.1...

Figure 1: Fluorophore intensity in the Drosophila blastoderm (n.c. 14). Comparison of (A) green and (B) red fluorescence intensity using the same intensity scaling in n.c. 14. The fluorescence signal did
not saturate. Shown are single imaging planes. Normalised histograms of fluorescence intensity for green (C) and red (D) fluorophores averaged across at least n=3 embryos per line. Scale bars = 20 μm

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Josh Currie @joshcurrie.bsky.social · 9d

Just a reminder if you're getting a manuscript together (like we are) to thank your core facilities!

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Reposted by Josh Currie

Paul Waldman @paulwaldman.bsky.social · 9d

1. More Americans work at the Cheesecake Factory than in the entire coal industry, and that won't change. It's because of automation, not snooty libs.

2. Coal energy is now more expensive than wind and solar.

3. So this means: higher energy prices, more pollution, no jobs benefit. Genius!

Aaron Rupar @atrupar.com · 9d

Energy Secretary Chris Wright on Fox: "We're announcing today expanded programs to help the American coal industry. We're helping it because for years it has been under assault. It was out of fashion with the chardonnay set in San Francisco, Boulder, and NYC ... coal just makes the world go round."

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Reposted by Josh Currie

DAPPER DON DHARSHI @dapperdondharshi.bsky.social · 10d

The platypus is possibly the weirdest animal: it's a mammal but lays eggs, its duck-billed, beaver-tailed, otter-footed and venomous. It has electroreceptors for locating prey, eyes with double cones, no stomach, and 26 pairs of chromosomes. It's fluorescent and glows under UV light.

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Josh Currie @joshcurrie.bsky.social · 10d

Bruschetta has been a nice, easy meal that the kids actually ask for.

Reposted by Josh Currie

Indivisible ❌👑 @indivisible.org · 10d

Trump’s regime knows they can’t silence us all through investigations, prosecutions or the deployment of brutal secret police. They can only try to silence dissent through fear. As long as we choose not to give into fear, we can’t be silenced. Join us to say NO KINGS: www.nokings.org?SQF_SOURCE=i...

(next to a map of the nearly 2,000 events planned for October 18) NO THRONES.
NO CROWNS.
NO KINGS.
SATURDAY, OCT. 18

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Josh Currie @joshcurrie.bsky.social · 11d

Coming into the weekend with a crash landing. Literally counting the hours till I can get the kids to sleep and pass out myself....

a man is walking down a hallway carrying a backpack .

ALT: a man is walking down a hallway carrying a backpack .

media.tenor.com

Reposted by Josh Currie

Lori O'Brien @llobrienlab.bsky.social · 11d

For this #FluorescenceFriday, a gorgeous image of an adult mouse kidney labeled with AQP2 and alpha SMA antibodies. AQP2 (green) marks the collecting duct and distal connecting segment while SMA marks the arterial tree. Courtesy of talented postdoc Sarah McLarnon.

Image of a fluorescently labeled adult mouse kidney showing AQP2 staining of collecting ducts and connecting segment in green and alpha SMA staining of the arterial tree in magenta. The collecting ducts look like squiggly branches.

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Reposted by Josh Currie

Miranda Yaver @mirandayaver.bsky.social · 12d

Honestly, this feels like the worst of American punditry. No expertise about public health or health policy, just “Here’s someone who’s doing heinous things that will literally kill people, so let’s see how it’s polling.”

Meg Tirrell @megtirrell.bsky.social · 12d

CNN Chief Data Analyst Harry Enten today on RFK Jr’s approval ratings

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Reposted by Josh Currie

Drug Monkey @drugmonkey.bsky.social · 12d

This may be the most important paper ever published about NIH funded research.

www.science.org/doi/10.1126/...

What if NIH had been 40% smaller?

Replaying history with less NIH funding shows widespread impacts on drug-linked research

www.science.org

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Reposted by Josh Currie

Mike Wiser @drmikewiser.bsky.social · 13d

I keep trying to get people to recognize that my having a PhD says a lot more about me being stubborn than me being smart.

Evan Torner @guyintheblackhat.bsky.social · 14d

PhDs aren't given to intelligent people.
They are earned by people who attempted something quite difficult, the creation of new subfield knowledge, and were both humbled and transformed by it.

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Reposted by Josh Currie

ryan cooper @ryanlcooper.com · 14d

a new mRNA therapy apparently can cut the rate of Huntington's disease progression by ~75%. yet more miracle shit www.bbc.com/news/article...

Huntington's disease successfully treated for first time

One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.

www.bbc.com

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