Juandi Hernández
@juandihc.bsky.social
Postdoc at @institutpasteur.bsky.social .Former PhD student at @cabd-upo-csic.bsky.social. Part time runner and cyclist. Betis fan. Views my own
Great news after the Christmas break! The work showing that CHCHD10 causes mitochondrial cardiomyopathy by disrupting intermembrane space proteostasis, impairing cytochrome c–dependent bioenergetics, and triggering maladaptive mtISR signaling—led by Márcio, a lab mate of mine— (1/3)
January 8, 2026 at 7:55 AM
Great news after the Christmas break! The work showing that CHCHD10 causes mitochondrial cardiomyopathy by disrupting intermembrane space proteostasis, impairing cytochrome c–dependent bioenergetics, and triggering maladaptive mtISR signaling—led by Márcio, a lab mate of mine— (1/3)
Reposted by Juandi Hernández
Good morning all! Here is the last weekly issue of the year in #cancermetabolism and #mitochondrialbiology to accompany your readings! biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading
"It is a serious thing, just to be alive on this fresh morning, in the broken world."-Mary Oliver
"It is a serious thing, just to be alive on this fresh morning, in the broken world."-Mary Oliver
bims-camemi 2025-12-28 papers
biomed.news
December 28, 2025 at 6:56 AM
Good morning all! Here is the last weekly issue of the year in #cancermetabolism and #mitochondrialbiology to accompany your readings! biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading
"It is a serious thing, just to be alive on this fresh morning, in the broken world."-Mary Oliver
"It is a serious thing, just to be alive on this fresh morning, in the broken world."-Mary Oliver
Reposted by Juandi Hernández
🆕 New update! Young Investigators Day will take place the day before EUROMIT 2026.
Don’t miss this unique chance for young scientists to connect and present your work !
👉 www.euromit2026.eu/article/youn...
#EUROMIT2026 #MitochondrialDisease #mtDNA #mitochondria
Don’t miss this unique chance for young scientists to connect and present your work !
👉 www.euromit2026.eu/article/youn...
#EUROMIT2026 #MitochondrialDisease #mtDNA #mitochondria
Young Investigator's day
www.euromit2026.eu
December 5, 2025 at 1:45 PM
🆕 New update! Young Investigators Day will take place the day before EUROMIT 2026.
Don’t miss this unique chance for young scientists to connect and present your work !
👉 www.euromit2026.eu/article/youn...
#EUROMIT2026 #MitochondrialDisease #mtDNA #mitochondria
Don’t miss this unique chance for young scientists to connect and present your work !
👉 www.euromit2026.eu/article/youn...
#EUROMIT2026 #MitochondrialDisease #mtDNA #mitochondria
Reposted by Juandi Hernández
Measuring mitochondrial membrane potential | The EMBO Journal www.embopress.org/doi/full/10....
Measuring mitochondrial membrane potential | The EMBO Journal
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
November 19, 2025 at 5:43 PM
Measuring mitochondrial membrane potential | The EMBO Journal www.embopress.org/doi/full/10....
Reposted by Juandi Hernández
The Friday crème brûlée is back! @institutpasteur.bsky.social
October 31, 2025 at 4:34 PM
The Friday crème brûlée is back! @institutpasteur.bsky.social
Last week, I had the great opportunity to present my postdoc project as a talk at the EMBO–FEBS meeting in Belgrade, Serbia. This work is being carried out at the Institut Pasteur @pasteur.fr. Grateful to the organizers for this inspiring and insightful event @embo.org bo.org @febspress.bsky.social
September 22, 2025 at 6:26 AM
Last week, I had the great opportunity to present my postdoc project as a talk at the EMBO–FEBS meeting in Belgrade, Serbia. This work is being carried out at the Institut Pasteur @pasteur.fr. Grateful to the organizers for this inspiring and insightful event @embo.org bo.org @febspress.bsky.social
Reposted by Juandi Hernández
🔬 "La science n'est pas une affaire d'opinion personnelle !"
Yasmine Belkaid, Directrice générale de l'Institut Pasteur, dénonce le démantèlement de la recherche US et réaffirme le rôle crucial de la science face aux défis sanitaires mondiaux.
↘️ www.lesechos.fr/idees-debats...
Yasmine Belkaid, Directrice générale de l'Institut Pasteur, dénonce le démantèlement de la recherche US et réaffirme le rôle crucial de la science face aux défis sanitaires mondiaux.
↘️ www.lesechos.fr/idees-debats...
September 5, 2025 at 8:28 AM
🔬 "La science n'est pas une affaire d'opinion personnelle !"
Yasmine Belkaid, Directrice générale de l'Institut Pasteur, dénonce le démantèlement de la recherche US et réaffirme le rôle crucial de la science face aux défis sanitaires mondiaux.
↘️ www.lesechos.fr/idees-debats...
Yasmine Belkaid, Directrice générale de l'Institut Pasteur, dénonce le démantèlement de la recherche US et réaffirme le rôle crucial de la science face aux défis sanitaires mondiaux.
↘️ www.lesechos.fr/idees-debats...
Reposted by Juandi Hernández
🟢 The Institut Pasteur goes green for Mitochondrial Disease Awareness Week! 🟢
These rare diseases affect 1 in 5,000 people. Mitochondria, the “powerhouses” of our cells, are also thought to play a role in Alzheimer's disease.
Research today, cure tomorrow. 🔬 #WorldMitoWeek2025
These rare diseases affect 1 in 5,000 people. Mitochondria, the “powerhouses” of our cells, are also thought to play a role in Alzheimer's disease.
Research today, cure tomorrow. 🔬 #WorldMitoWeek2025
September 17, 2025 at 9:11 AM
🟢 The Institut Pasteur goes green for Mitochondrial Disease Awareness Week! 🟢
These rare diseases affect 1 in 5,000 people. Mitochondria, the “powerhouses” of our cells, are also thought to play a role in Alzheimer's disease.
Research today, cure tomorrow. 🔬 #WorldMitoWeek2025
These rare diseases affect 1 in 5,000 people. Mitochondria, the “powerhouses” of our cells, are also thought to play a role in Alzheimer's disease.
Research today, cure tomorrow. 🔬 #WorldMitoWeek2025
Reposted by Juandi Hernández
Mitochondria protect against an intracellular pathogen by restricting access to folate | Science www.science.org/doi/10.1126/...
Mitochondria protect against an intracellular pathogen by restricting access to folate
As major consumers of cellular metabolites, mitochondria are poised to compete with invading microbes for the nutrients that they need to grow. Whether cells exploit mitochondrial metabolism to protec...
www.science.org
August 15, 2025 at 5:06 AM
Mitochondria protect against an intracellular pathogen by restricting access to folate | Science www.science.org/doi/10.1126/...
Reposted by Juandi Hernández
"I think that in Europe there is a better balance than in other places in terms of life, personal life and professional life."
Nicolás Rascovan, Argentinian researcher at @pasteur.fr, Paris.
#ChooseEuropeForScience
Nicolás Rascovan, Argentinian researcher at @pasteur.fr, Paris.
#ChooseEuropeForScience
August 10, 2025 at 11:30 AM
"I think that in Europe there is a better balance than in other places in terms of life, personal life and professional life."
Nicolás Rascovan, Argentinian researcher at @pasteur.fr, Paris.
#ChooseEuropeForScience
Nicolás Rascovan, Argentinian researcher at @pasteur.fr, Paris.
#ChooseEuropeForScience
Here we go—ready for another adventure! 👨🏻🔬🧫
July 10, 2025 at 10:08 AM
Here we go—ready for another adventure! 👨🏻🔬🧫
Reposted by Juandi Hernández
Beautiful cartoons on the grids of the Institute illustrating our future research centre on vector-borne diseases @pasteur.fr with lovely #trypanosomes and a tsetse fly 😉
Many thanks to Céleste Gangolphe for the exceptional work!
Many thanks to Céleste Gangolphe for the exceptional work!
July 4, 2025 at 11:27 AM
Beautiful cartoons on the grids of the Institute illustrating our future research centre on vector-borne diseases @pasteur.fr with lovely #trypanosomes and a tsetse fly 😉
Many thanks to Céleste Gangolphe for the exceptional work!
Many thanks to Céleste Gangolphe for the exceptional work!
Reposted by Juandi Hernández
He convertido la reacción que preparé para @sciencemediacentre.es a este artículo en @plosbiology.org sobre propuestas innovadoras terapéuticas con nuevos editores de bases para enfermedades mitocondriales en entrada en mi blog #gen_ética en @naukas.bsky.social
montoliu.naukas.com/2025/06/29/c...
montoliu.naukas.com/2025/06/29/c...
Cómo resolver las limitaciones de las CRISPR para editar el genoma de las mitocondrias - Gen-Ética
La microbióloga Lynn Margulis pasará a la historia de la biología por haber propuesto la teoría endosimbiótica del origen de las células eucariotas (las que forman el cuerpo de levaduras, […]
montoliu.naukas.com
June 29, 2025 at 9:08 AM
He convertido la reacción que preparé para @sciencemediacentre.es a este artículo en @plosbiology.org sobre propuestas innovadoras terapéuticas con nuevos editores de bases para enfermedades mitocondriales en entrada en mi blog #gen_ética en @naukas.bsky.social
montoliu.naukas.com/2025/06/29/c...
montoliu.naukas.com/2025/06/29/c...
Reposted by Juandi Hernández
Reposted by Juandi Hernández
#PodcastCNRS 🎧 Saviez-vous que plus de 40 % de notre masse corporelle est composée de muscles ? 💪
La biologiste Bénédicte Chazaud étudie leur capacité de régénération et ce qui bloque le processus quand le corps est malade.
👉 smartlink.ausha.co/cnrs-qu-est-...
La biologiste Bénédicte Chazaud étudie leur capacité de régénération et ce qui bloque le processus quand le corps est malade.
👉 smartlink.ausha.co/cnrs-qu-est-...
June 10, 2025 at 4:20 PM
#PodcastCNRS 🎧 Saviez-vous que plus de 40 % de notre masse corporelle est composée de muscles ? 💪
La biologiste Bénédicte Chazaud étudie leur capacité de régénération et ce qui bloque le processus quand le corps est malade.
👉 smartlink.ausha.co/cnrs-qu-est-...
La biologiste Bénédicte Chazaud étudie leur capacité de régénération et ce qui bloque le processus quand le corps est malade.
👉 smartlink.ausha.co/cnrs-qu-est-...
Reposted by Juandi Hernández
New #NatureComms paper: Complementing muscle regeneration—fibro-adipogenic progenitor and macrophage-mediated repair of elderly human skeletal muscle. #Myoblue tinyurl.com/yvr65vm9
Complementing muscle regeneration—fibro-adipogenic progenitor and macrophage-mediated repair of elderly human skeletal muscle - Nature Communications
Successful skeletal muscle regeneration involves a complex and finely tuned inter-cellular response. Here, by using spatial transcriptomics, the authors identify an intercellular communication axis be...
tinyurl.com
June 6, 2025 at 11:58 AM
New #NatureComms paper: Complementing muscle regeneration—fibro-adipogenic progenitor and macrophage-mediated repair of elderly human skeletal muscle. #Myoblue tinyurl.com/yvr65vm9
Reposted by Juandi Hernández
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
May 21, 2025 at 3:05 PM
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
Reposted by Juandi Hernández
Reposted by Juandi Hernández
Reposted by Juandi Hernández
Molecular machineries shaping the mitochondrial inner membrane.
Molecular machineries shaping the mitochondrial inner membrane - Nature Reviews Molecular Cell Biology
The inner mitochondrial membrane forms cristae, which are crucial for mitochondrial function. This Review explores the protein complexes that regulate cristae dynamics, including remodelling and fusio...
www.nature.com
May 15, 2025 at 2:11 AM
Molecular machineries shaping the mitochondrial inner membrane.
Reposted by Juandi Hernández
Reposted by Juandi Hernández
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress | Science Advances www.science.org/doi/10.1126/...
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress
Quantitative imaging of the mitochondrial central dogma identifies translation hubs that are suppressed during stress.
www.science.org
April 18, 2025 at 10:39 PM
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress | Science Advances www.science.org/doi/10.1126/...
Reposted by Juandi Hernández
Happy to share our most recent review on mitochondria-organelle metabolic communication with Yatrik Shah and Costas Lyssiotis now online at Molecular Cell!
We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals!
www.sciencedirect.com/science/arti...
We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals!
www.sciencedirect.com/science/arti...
Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis
Mitochondria serve as central hubs in cellular metabolism by sensing, integrating, and responding to metabolic demands. This integrative function is a…
www.sciencedirect.com
April 17, 2025 at 9:24 PM
Happy to share our most recent review on mitochondria-organelle metabolic communication with Yatrik Shah and Costas Lyssiotis now online at Molecular Cell!
We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals!
www.sciencedirect.com/science/arti...
We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals!
www.sciencedirect.com/science/arti...
Reposted by Juandi Hernández
🔥🔥🔥 New preprint!
Our new work explores the dynamic behaviour of muscle stem cells and their niche interactions in Duchenne Muscular Dystrophy.
www.biorxiv.org/content/10.1... #MyoBlue
Our new work explores the dynamic behaviour of muscle stem cells and their niche interactions in Duchenne Muscular Dystrophy.
www.biorxiv.org/content/10.1... #MyoBlue
Impaired stem cell migration and divisions in Duchenne Muscular Dystrophy revealed by live imaging
Dysregulation of stem cell properties is a hallmark of many pathologies, but the dynamic behaviour of stem cells in their microenvironment during disease progression remains poorly understood. Using t...
www.biorxiv.org
March 14, 2025 at 3:23 PM
🔥🔥🔥 New preprint!
Our new work explores the dynamic behaviour of muscle stem cells and their niche interactions in Duchenne Muscular Dystrophy.
www.biorxiv.org/content/10.1... #MyoBlue
Our new work explores the dynamic behaviour of muscle stem cells and their niche interactions in Duchenne Muscular Dystrophy.
www.biorxiv.org/content/10.1... #MyoBlue
Reposted by Juandi Hernández
Interested in the plasmidverse? Then, don't think twice and join the International Society for Plasmid Biology Virtual Seminars Series. 👇
January 16, 2025 at 8:26 AM
Interested in the plasmidverse? Then, don't think twice and join the International Society for Plasmid Biology Virtual Seminars Series. 👇