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Julia Eckert

@juliaeckert.bsky.social

1.8K followers 430 following 82 posts

@dfg.de Walter Benjamin Fellow & Postdoctoral Researcher @yap-lab.bsky.social | Co-organizer @epimechfc.bsky.social | Mechanobiology - Cell & Tissue Mechanics - Soft Matter Physics - Image Analysis 👉 https://julia-eckert.github.io

julia-eckert.github.io

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Julia Eckert @juliaeckert.bsky.social · Aug 15

Now published in @natcomms.nature.com! 🥳

👉 rdcu.be/eATn3

We developed image analysis tools to capture the nematic orientation field of 3D tissue surfaces. Tested on epithelial aggregates, zebrafish hearts, myoblasts on spheres & micro-vessels, we combined soft matter physics with exp. biology.

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Reposted by Julia Eckert

Nature Reviews Physics @natrevphys.nature.com · 1d

Mechanobiology across timescales

A Review by Bo Cheng, Moxiao Li, Min Lin, Hui Guo & Feng Xu ⚛️🧪
www.nature.com/articles/s42...

Mechanobiology across timescales - Nature Reviews Physics

This Review explores how cells sense and respond to mechanical signals across timescales. By integrating mechanosensing at membranes, mechanotransduction in the cytoplasm, and nuclear reprogramming, it reveals a role of temporal dynamics in tissue development and disease.

www.nature.com

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Reposted by Julia Eckert

Nature @nature.com · 1d

John Clarke, Michel Devoret and John Martinis have been awarded the 2025 Nobel Prize in Physics for demonstrating quantum physics on the macroscopic scale

go.nature.com/3WnEUhE

Groundbreaking quantum-tunnelling experiments win physics Nobel

John Clarke, Michel Devoret and John Martinis discovered quantum physics on a macroscopic scale, paving the way for quantum computing.

go.nature.com

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Reposted by Julia Eckert

Sam Aytekin @samaytekin.bsky.social · 2d

Garcia Lab did it again! Such a fantastic read if you are interested in FAs mechanics and biology. Congratulations to @garcialabgt.bsky.social

Mechanochemical waves in focal adhesions during cell migration

Traction force and FAK signaling exhibit oscillatory temporal coupling in adhesive structures.

www.science.org

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Reposted by Julia Eckert

Juanma García-Arcos @juanmagararc.bsky.social · 3d

🚨 New preprint out!
“Fluorescence lifetime estimation: a practical approach using Flipper-TR FLIM” with Tithi Mandal and @rouxlab.bsky.social
We benchmark and describe step-by-step Flipper-TR FLIM measurements across different set-ups and and strategies.

www.biorxiv.org/content/10.1...

Fluorescence lifetime estimation: a practical approach using Flipper-TR FLIM

Flipper-TR is a membrane dye sensitive to lipid packing widely used to probe membrane tension in live cells via fluorescence lifetime imaging microscopy (FLIM). However, no consensus currently exists ...

www.biorxiv.org

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Reposted by Julia Eckert

epithelial mechanics fan club @epimechfc.bsky.social · 4d

How do dynamic forces influence symmetry-breaking in embryonic development?

Hi, I’m @dr-rajendra-s-negi.bsky.social & in this thread, I’d like to introduce some aspects of the interdisciplinary research on tissue dynamics.

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Reposted by Julia Eckert

Maik Bischoff @maikbischoff.bsky.social · 5d

My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing
🔵 lifeact &
🔴 RFP-nls

Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨

🔗 www.nikonsmallworld.com/galleries/20...

#NikonSmallWorld #Microscopy #ScienceArt

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Julia Eckert @juliaeckert.bsky.social · 5d

😍 nematic order 😍 can I analyze it?

Reposted by Julia Eckert

James Briscoe @jamesbriscoe.bsky.social · 5d

Mechanical constraints disrupt gastruloid polarisation without changing gene expression - uncouples morphogenesis & patterning

Gregor & co use tunable hydrogels to show cell motility, not gene expression, drives axis formation in gastruloids

journals.biologists.com/dev/article/...

Fine-tuning mechanical constraints reveals uncoupled patterning and gene expression programs in murine gastruloids

Highlighted Article: A bioinert confinement system enables dissection of how stiffness and timing shape gastruloid development, revealing uncoupling between polarization and transcriptional programs.

journals.biologists.com

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Reposted by Julia Eckert

arXiv cond-mat.soft Soft Condensed Matter @condmatsoft-bot.bsky.social · 5d

Lea Happel, Griseldis Oberschelp, Anneli Richter, Gwenda Roselene Rode, Valeriia Grudtsyna, Amin Doostmohammadi, Axel Voigt: A spectrum of p-atic symmetries and defects in confluent epithelia https://arxiv.org/abs/2510.02160 https://arxiv.org/pdf/2510.02160 https://arxiv.org/html/2510.02160

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Julia Eckert @juliaeckert.bsky.social · 6d

Excited to participate in the Scientific Art Contest at #CellMech2025.

Julia Eckert @juliaeckert.bsky.social · 6d

@epimechfc.bsky.social discussion with @dedenonmathieu.bsky.social at #CellMech2025 :)

CellMech2025 @cellmech2025.bsky.social · 6d

Coffee break in full swing at #cellmech2025 —fueling up for the next session!

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Reposted by Julia Eckert

myosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 6d

www.nature.com/articles/s41...

Dynamic rigidity changes enable rapid cell migration on soft substrates - Nature Communications

Cells struggle to migrate on soft substrates, which don’t provide enough traction. Here, the authors show that rapid, cyclic changes in substrate rigidity allow cells to overcome this limitation and move quickly.

www.nature.com

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Reposted by Julia Eckert

Kate Cavanaugh @katecavanaugh.bsky.social · 7d

See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...

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Reposted by Julia Eckert

Theory of Living Matter Group @tlmcambridge.bsky.social · 7d

🚨New academic year calls for a new lineup of speakers. ✍️Sign up to our mailing list to hear these wonderful array of speakers this term. Please reshare among your networks 📩 lists.cam.ac.uk/sympa/subscr...

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Reposted by Julia Eckert

MOSAIC Group / Sbalzarini Lab @mosaicgroup.bsky.social · 7d

🤩👍🏼💪🏼 Meet #TopoSPAM - a high-performance simulation platform for biological morphogenesis with a friendly Python interface. @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de. Solve both continuous and discrete active mechanics! Released today: arxiv.org/abs/2509.24905

TopoSPAM: Topology grounded Simulation Platform for morphogenesis and biological Active Matter

We present a topology grounded, multiscale simulation platform for morphogenesis and biological active matter. Morphogenesis and biological active matter represent keystone problems in biology with ad...

arxiv.org

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Reposted by Julia Eckert

arXiv cond-mat.soft Soft Condensed Matter @condmatsoft-bot.bsky.social · 7d

Xie, Modak, Usman, Tan, Coca, De Jesus, Wang, Thirumalai, Li, Irianto: Rotational migration in human pancreatic ductal organoids depends on actin and myosin activity https://arxiv.org/abs/2509.25680 https://arxiv.org/pdf/2509.25680 https://arxiv.org/html/2509.25680

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Reposted by Julia Eckert

Joachim Goedhart @joachimgoedhart.bsky.social · 8d

Identification of optimal fluorophores for use in the Drosophila embryo by Timothy E Saunders and team: www.biorxiv.org/content/10.1...

Figure 1: Fluorophore intensity in the Drosophila blastoderm (n.c. 14). Comparison of (A) green and (B) red fluorescence intensity using the same intensity scaling in n.c. 14. The fluorescence signal did
not saturate. Shown are single imaging planes. Normalised histograms of fluorescence intensity for green (C) and red (D) fluorophores averaged across at least n=3 embryos per line. Scale bars = 20 μm

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Reposted by Julia Eckert

Guillaume Charras @gcharras.bsky.social · 9d

Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients.

More here: elifesciences.org/reviewed-pre...

elifesciences.org

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Reposted by Julia Eckert

Akankshi Munjal @akankshi.bsky.social · 12d

Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd

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Reposted by Julia Eckert

bioRxiv Biophysics @biorxiv-biophys.bsky.social · 12d

Fluorescence lifetime estimation: a practical approach using Flipper-TR FLIM https://www.biorxiv.org/content/10.1101/2025.09.23.678124v1

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Reposted by Julia Eckert

Maik Bischoff @maikbischoff.bsky.social · 14d

1/12 A very special moment for me! 🎉

My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.

rupress.org/jcb/article/...

#cellbio #devbio #science

🧵for details

Cartoon of a speculative heterogenous cell population performing mesenchymal collective cell migration.

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Reposted by Julia Eckert

Barriga Lab @eliasbarrigalab.bsky.social · 15d

Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!

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Julia Eckert @juliaeckert.bsky.social · 15d

Congrats @philipschoene.bsky.social 🥳

Reposted by Julia Eckert

Felix Campelo @felixmendu.bsky.social · 16d

🧵 I've been meaning to write a #Skytorial on our recently posted prepring in which we show evidence that the Golgi 🥞 is a mechanoresponsive organelle. Extracellular mechanical forces also tune Golgi export capacity! 👉 www.biorxiv.org/content/10.1...

Mechanical forces stimulate Golgi export

Human cells face a wide range of external mechanical stimuli that vary with cell type, state, and pathological conditions. The rapidly growing field of mechanobiology investigates how cells sense and ...

www.biorxiv.org

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Julia Eckert @juliaeckert.bsky.social · 17d

All the best, Ricard, and have a good start in Barcelona!