Excited to share some of my PhD work on ubiquitin www.biorxiv.org/content/10.1...!

Huge collaborative effort from many people

Check out the whole story here

We are back with an exciting seminar on September 8 at 3pm CEST! We’ll hear from Prof. Birthe Kragelund and Maximilian Vieler (@uu.se).

Register to attend:
tinyurl.com/PMCseminar2

Recordings of previous seminars: www.youtube.com/@PMCModularity

Check out our latest preprint where we show synergistic interactions between bacteria for the degradation of complex polysaccharides 🌊🦠🔺
@envsysmicro.at @akshitg.bsky.social
#MicroSky
www.biorxiv.org/content/10.1...

New blog post: Why do we still publish in scientific journals ? What is holding us back from letting go of traditional publishing? No major insight here but I am curious what others think. www.evocellnet.com/2025/07/why-...

Unexpectedly, @jurgjn.bsky.social found that running Alphafold3 predictions for protein interactions can yield ipTM scores that are more predictive of true interactions when run in pools of proteins instead of pairwise predictions. Presumably, this reflects some sort of "competition effect".

TIME CHANGE - Because of a public holiday, we have moved the next seminar to Monday June 16 at 3pm CET. Tune in to hear from Dr. Lucía Chemes (@unsamoficial.bsky.social) and Julian van Gerwen (@julianvangerwen.bsky.social).

Register to attend:
tinyurl.com/PMCseminar2

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Thanks Lars!

Increasing the time limits post PhD for ERC starting grant applications is a bad idea. It will mean fewer junior PIs getting an ERC at the start of the group. Those complaining about the previous time limits will not really benefit. The competition will be higher.
erc.europa.eu/news-events/...

We present SELPHI 2.0 a machine learning model integrating >40 sequence, omics and structural features to predict kinase-substrate interactions between 420 kinases and 240K phosphosites and improve interpretation of global phosphoproteomics data www.sciencedirect.com/science/arti...

Excited to share some of our work on ubiquitin at this seminar!

We utilized protein kinases to probe substrate protein structures. The phosphate groups enabled selective extraction of labeled sites.
Detecting Protein Higher-Order Structural Changes Using Kinase as a Phospho-Labeler www.biorxiv.org/content/10.1...

It was a pleasure to attend this amazing meeting! Huge thanks to the organisers

Join us at 6pm CET April 14 for the next seminar in our series with Prof. Anne-Claude Gingras (@uoft.bsky.social) and Dr. Veronica Venafra.

Register to attend: tinyurl.com/register-pmc-seminar
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New blog post - State of the lab 12, yearly series on being a group leader in academia. This one reflects back on the transition from junior PI to a more established scientist www.evocellnet.com/2025/03/stat...