Lightnews — Scholar-powered news

Reposted by Evangelia Petsalaki

Saez-Rodriguez Group @saezlab.bsky.social · 21d

🥁 Check out our new preprint on OmniPath, the prior knowledge resource for #SystemsBiology, and its brand-new OmniPath Explorer web app! 🥳

📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org

OmniPath integrates 160+ resources for multi-omics analysis & modeling.

🧶⬇️

1 20 35

Reposted by Evangelia Petsalaki

Pedro Beltrao @pedrobeltrao.bsky.social · 17h

Our group has a PhD position open in this Doctoral network. Our topic is around combining proteomics AI and protein structures. Look through the website below to look at all of the projects/groups and apply.

protaiomics.bsky.social @protaiomics.bsky.social · 18h

🌟Ready to apply?
16 fully funded PhD positions are open in ProtAIomics Doctoral Network!
Join 16 labs across Europe to advance AI-powered proteomics and drive discoveries in health & biotechnology.
👉 Apply here: www.protaiomics.eu
#Proteomics #ArtificialIntelligence #MSCA #PhDOpportunities

5 8

Reposted by Evangelia Petsalaki

Lukas Käll @lukaskall.bsky.social · 15h

There is a position open in our lab, within this network. Our project deals with assessing identification and quantification errors for MS-based proteomics. www.protaiomics.eu/project/dc13...
Please check out all the project descriptions at the site below:

9 7

Reposted by Evangelia Petsalaki

CortésLab @corteslab.bsky.social · 4d

Kickstarting our Bluesky🦋 account with great news!
Our REPAIRome study finally out today in
@science.org
www.science.org/doi/10.1126/...

A comprehensive genetic catalog of human double-strand break repair

The analysis of DNA sequence outcomes provides molecular insights into double-strand break (DSB) repair mechanisms. Using parallel in-pool profiling of Cas9-induced insertions and deletions (indels) w...

www.science.org

7 26 71

Reposted by Evangelia Petsalaki

BIOMICS_GIMM @biomics-twinning.bsky.social · 2d

✨ Getting to know BIOMICS members ✨
Meet the people behind our #Twinning project one story at a time.
🎙️ Who’s our first guest?
Hint: a Group Leader at ETH Zurich exploring how molecular mechanisms shape human biology and disease.

Here ➡️ youtu.be/iqlB74ldyos
#HorizonEurope #BIOMICS #MeetTheTeam

Getting to know BIOMICS members: Pedro Beltrão

YouTube video by BIOMICS Twinning

youtu.be

1 4 6

Reposted by Evangelia Petsalaki

BIOMICS_GIMM @biomics-twinning.bsky.social · 2d

@nmoraislab.bsky.social @pedrobeltrao.bsky.social @mirimiam.bsky.social @epetsalaki.bsky.social

1 1

Reposted by Evangelia Petsalaki

Benjamin Maier @bdmaier.bsky.social · 3d

Excited to present my talk "Data-Driven Mathematical Modelling to Improve Heart Organoid Design" in the Therapeutic Target Discovery module at #ICSB2025 in Dublin tomorrow at 3:20 pm! 🫀💻 @epetsalaki.bsky.social @ebi.embl.org

1 2 6

Reposted by Evangelia Petsalaki

Benjamin Maier @bdmaier.bsky.social · 3d

Also don’t miss:
🧬👯 @epetsalaki.bsky.social’s talk “From Data to Digital Twins” (Wed, Digital Twin Models)

📊🧬 My poster P03.14 – Towards Data-Driven Executable Models (Wed)

🧩🤖 @alussana.bsky.social’s poster P18.13 – Data-Driven Inference of Functionally Coherent Gene Modules (Mon)

2 2

Reposted by Evangelia Petsalaki

John Lees @bacpop.org · 9d

Now published, our tool to run (almost) all biological models interactively in your web browser

Paper: academic.oup.com/bioinformati...
Website: biomodels.bacpop.org
Code: github.com/bacpop/SBMLt...

1 9 15

Reposted by Evangelia Petsalaki

Ylva Ivarsson @ivarssonlab.bsky.social · 16d

Finally out! Thrilled to share our collaboration with @kulathu.bsky.social, @orafurman.bsky.social, and N Davey. We screened auxiliary domains of USP family #deubiquitinases, revealing short linear motifs (SLiMs), contributing to specificity in complex assembly.
www.biorxiv.org/content/10.1...

Systematic Discovery of Motif-based Interactions of the Auxiliary Domains of USP Family Deubiquitinases

The ubiquitin-specific proteases (USPs) family is the largest family of human deubiquitinating enzymes (DUBs). While most USPs are agnostic to polyubiquitin linkage-type, their substrate specificity i...

www.biorxiv.org

1 6 12

Evangelia Petsalaki @epetsalaki.bsky.social · 21d

Join us for this exciting meeting!

Francesco Iorio @francescoiorio.bsky.social · 21d

📢 The 2nd European Cancer Dependency Map Symposium is coming!
🗓️ 20 Nov 2025
📍 Human Technopole, Milan
Join us for a one-day dive into:
🔹 Cancer genomics
🔹 CRISPR screening
🔹 AI-driven target discovery
With the patronage of AIRC
🔗 humantechnopole.it/en/trainings...

2nd European Cancer Dependency Map Symposium - Human Technopole

The 2nd European Cancer Dependency Map Symposium is a scientific event open to the national and international scientific community working in computational genomics, pharmacogenomics, and therapeutic ...

humantechnopole.it

1 1

Reposted by Evangelia Petsalaki

IorioLab @ioriolab.bsky.social · 22d

Francesco will be speaking at the High-Content CRISPR Screening conference, taking place March 18–19, 2026 in Vienna 🇦🇹 alongside leading experts in CRISPR screening, functional genomics, and drug discovery
www.linkedin.com/posts/myllia...

The registration and abstract submission for the "High-Content CRISPR Screening" conference on March 18–19, 2026, in Vienna, Austria is now open! Secure your spot via the conference website...

The registration and abstract submission for the "High-Content CRISPR Screening" conference on March 18–19, 2026, in Vienna, Austria is now open! Secure your spot via the conference website: https://...

www.linkedin.com

2 3

Reposted by Evangelia Petsalaki

EMBL @embl.org · 27d

For additional open calls for leadership roles at EMBL, also check out: embl.wd103.myworkdayjobs.com/EMBL

We’re looking for:
Hamburg: Group Leader
Grenoble: Group Leader
Heidelberg: Two Group Leaders, Team Leader, Unit Head

8 5

Reposted by Evangelia Petsalaki

Max-Planck-Gesellschaft @maxplanck.de · 29d

Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer

2 56 52

Reposted by Evangelia Petsalaki

Beatriz Urda @beatrizurda.bsky.social · Sep 2

🚨 New in PNAS!
🧬 64% of disease co-occurrences can be explained by transcriptomic similarities.

Comorbidities aren’t random—they have a molecular basis.

Here’s how we found it 👇 (1/n)

🔗 doi.org/10.1073/pnas.2421060122

@alfonsovalencia.bsky.social

1 14 27

Reposted by Evangelia Petsalaki

EMBL @embl.org · Sep 1

📢 Recruitment for the EMBL International PhD Programme is officially open!

At EMBL, we train young scientists to become skilled and creative future leaders in academia and other sectors. Join us and get a head start on your career in life sciences!

bit.ly/47mmiFF

43 39

Reposted by Evangelia Petsalaki

Thiago Carvalho @cyrilpedia.bsky.social · Aug 27

'The Computation & Theory research area at Janelia seeks exceptional Group Leaders to advance our understanding of complex biological systems through theory, computational modeling, multi-modal data integration, and interpretable machine learning.'
#ScienceJobs
www.janelia.org/content/lead...

Lead a lab at Janelia

www.janelia.org

5 4

Reposted by Evangelia Petsalaki

Daniel Durocher @durocher1.bsky.social · Aug 28

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.

www.nature.com/naturecareer...

Please repost!

170 130

Reposted by Evangelia Petsalaki

Colm Ryan @colmr.bsky.social · Aug 20

Monumental effort from @maxbillmann.bsky.social and colleagues, quantifying genetic interactions among 4 million human gene pairs. Lots of features associated with genetic interaction & GI degree conserved from yeast. www.biorxiv.org/content/10.1...

A global genetic interaction map of a human cell reveals conserved principles of genetic networks

We generated a genome-scale, genetic interaction network from the analysis of more than 4 million double mutants in the haploid human cell line, HAP1. The network maps ∼90,000 genetic interactions, in...

www.biorxiv.org

1 4 8

Evangelia Petsalaki @epetsalaki.bsky.social · Jul 30

Very happy to have collaborated with Yifei and Jaime in these exciting projects!

EMBL-EBI @ebi.embl.org · Jul 30

A poster, a conversation, and a cross-Atlantic collaboration where bioinformatics meets neuroscience to uncover new insights into Alzheimer’s disease 🌍🧠

www.ebi.ac.uk/about/news/t...
#Alzheimers 🖥️🧬

From bench to code: collaboration unlocks insights into Alzheimer’s disease

How a chance encounter resulted in a fruitful cross-Atlantic research collaboration

www.ebi.ac.uk

2

Reposted by Evangelia Petsalaki

Fabian Theis @fabiantheis.bsky.social · Jul 9

Thrilled to collaborate with Mathew Garnett @Sanger and Parse Biosciences on the new Cancer Plasticity Atlas – a hugely exciting single cell genomics resource to decode tumor adaptation. 🔗 helmholtz-munich.de/en/newsroom/news-all/artikel/cancer-plasticity-atlas-to-improve-cancer-therapies

Helmholtz Munich

Helmholtz Munich, is a member of the Helmholtz Association of German Research Centres

helmholtz-munich.de

1 2 20

Evangelia Petsalaki @epetsalaki.bsky.social · Jul 9

Deadline this Sunday!

Evangelia Petsalaki @epetsalaki.bsky.social · Jun 30

Do you have experience in mechanistic modelling of biological systems and want to do a postdoc with an interdisciplinary team on developing Digital Twins for rare disease? We have the job for you! Check it out below - deadline July 13th, online interviews 24th July.

Evangelia Petsalaki @epetsalaki.bsky.social · Jun 24

Your weekly reminder that there is a really fun post @ebi.embl.org in our group in collaboration with Sheriff Rahuman (@biomodels) and Ellie McDonagh (@opentargets) to create Digital Twins for rare disease using multiomics, executable modelling and AI. Join our interdisciplinary team! Deadline 13/07

Reposted by Evangelia Petsalaki

Charlotte Hutchings @charlh-science.bsky.social · Jul 7

Having held this position for almost three years, I can say it’s a super friendly and fun committee to be involved in! Reach out if you have any questions 🙂

British Society for Proteome Research @ukbspr.bsky.social · Jul 7

We are looking for a student representative for BSPR. Its an exciting opportunity to be more involved with the society anf help shape its future. Please do consider joining #bspr2025

3 8

Reposted by Evangelia Petsalaki

Sriram Pendyala @treependyala.bsky.social · Jul 7

🚨 Most variant screens measure growth or abundance. What do they miss? That variants impact a spectrum of protein and cellular phenotypes. Variant in situ sequencing (VIS-seq) finds what’s missing: image cells 🔬 first, decode later, revealing multi-scale phenotypes for thousands of variants.👇

1/9

2 18 47

Reposted by Evangelia Petsalaki

British Society for Proteome Research @ukbspr.bsky.social · Jul 7

Our first plenary session starts with @slavov-n.bsky.social telling us about single cell proteomics and moving it to biological function

6 21