I've had Sakaguchi papers on my desk since '99, when I was warned against studying cells (Treg) that may not exist. 26 years on, we've shown you need them to reproduce and we may bring them to Heart clinics. A joyous overdue toast to Sakaguchi's steadfast building of the foundations of our science!

A long-awaited consensus statement on inflammation and heart disease
"We have thus entered an era when the evidence linking inflammation with ASCVD is no longer exploratory but is
compelling and clinically actionable."
@jaccjournals.bsky.social open-access
www.jacc.org/doi/10.1016/...

'(...) deciphering the interactions between ab-mediated immunity & viral evolution will be key. In this perspective, we explore these dynamic relationships & highlight research priorities that may guide the dev. of more effective strategies to mitigate the impact of emerging infectious diseases.'

We don't make the journal cover often (indeed this is only the second time ever). We don't even publish that often. But this paper took very many years of work, from very many people, and I am wholeheartedly grateful to each and every one of them.

A comprehensive collection of insights and ideas on #aging and how to treat its associated diseases. Honoured to have been involved, with many thanks to @stelloslab.bsky.social for the herculean feat of coordination.
www.nature.com/articles/s41...

Happy to share our latest paper in JITC, exploring the “bottom of the iceberg” of tumor immunotherapy myocarditis with MRI. Defining this is important for survivors, as we wait for prognosis and therapy tools. Many thanks to all onco/cardio/radio/immunologists involved: jitc.bmj.com/content/13/3...