Kat Holt
@katholt.bsky.social
3.9K followers 350 following 140 posts
Scientist… pathogen genomics & antimicrobial resistance, computational biology & infectious disease epidemiology. Co-Director LSHTM AMR Centre @lshtmamrcentre.bsky.social holtlab.net | klebnet.org | typhoidgenomics.org | amr.lshtm.ac.uk
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Reposted by Kat Holt
sandylaping.bsky.social
you can read about all the actions here: www.trumpactiontracker.info?
it's chilling and it's getting worse, but we won't stop chronicling what's happening.. looking away is not an option
Reposted by Kat Holt
pamferretti.bsky.social
Manually curated and harmonized metadata for over 110k metagenomic samples! (58k samples from the human gut alone!)🦠

Proud to have contributed to Metalog, the latest @borklab.bsky.social resource:

www.biorxiv.org/content/10.1...

#microsky #microbiome
Reposted by Kat Holt
samdolan.bsky.social
Oh come on. This is so weak. You made a mistake by admitting Musk as a Fellow in the first place. High time to reverse that mistake. Strip him of his Fellowship. He's dragging your reputation through the mud. The longer you dilly-dally, the worse it gets.
Reposted by Kat Holt
dutchscientist.bsky.social
Stoopid, just stupid. He should have never been made a fellow, but now Melon needs to be booted out with force. With prejudice.

Cowardly behaviour from the society. Don't expect any support or understanding for this. You blundered and are refusing to make it right, just because you're scared.
Reposted by Kat Holt
dieworkwear.bsky.social
Jane Goodall was my first childhood hero, as I loved animals as a kid and was inspired by her story. I still remember the National Geographic specials about her. RIP.
Jane Goodall reaches out and touches a small monkey.
katholt.bsky.social
They are entirely missing the point, pretending Elon is a scientist like any other just doing his best & exercising free speech (would say academic freedom, but noone’s pretending he’s an academic). That is not what is going on.

This lays out what we are really up against.

bsky.app/profile/scie...
sciencevs.bsky.social
This moment from our latest episode with science writer @edyong209.bsky.social is 🔥

We asked Ed — how do we talk up the benefits of science in the face of government cuts? He told us that's the wrong approach. 🧪

Listen wherever, or watch on Spotify 👇

open.spotify.com/episode/7Evh...
Reposted by Kat Holt
scurry.bsky.social
I am so dismayed a the statement today from the President of the @royalsociety.org that I want to publish here the letter I wrote to him yesterday urging him to address the clear concerns of the UK scientific community.
Screenshot of first part of letter (continues in next image). Text reads: 

Dear Sir Adrian

I write to request that in its deliberations tomorrow the Council resolves to take a principled stand to defend the scientific values written into its code of conduct. 

In its attempts to deal with the actions of Elon Musk FRS, the Royal Society has repeatedly failed to explain how his repudiation of those values is consistent with the code of conduct that all Fellows must adhere to as a condition of their fellowship. As is now well established, these actions include attacking Antony Fauci FRS without good cause; spreading scientific misinformation on X [through his own utterances and by relaxing controls on the platform]; recklessly and unlawfully degrading the research ecosystem of the US as part of DOGE; and bragging publicly about "feeding USAID into the wood chipper", which the Lancet estimates will cause the deaths of 14 million people, many of them children under the age of five, by 2030. 

The Society’s inaction extends to the recent brief exchange of correspondence between Prof Sir Paul Nurse and Mr Musk. Although there was some initial contact, when Sir Paul laid out the Society’s specific concerns there was no reply or explanation from Musk. For reasons that I’m afraid I cannot fathom, you chose once again not to enforce your code of conduct. 
Screenshot of letter. Text continues: 

"You will be aware that the sense of bewildered dismay over this affair is shared by Royal Society Fellows, medallists and journals editors, and many thousands within the scientific community here and abroad. The Royal Society still claims to speak for scientists in the UK, but on this vital issue, its inaction represents an inexplicable rupture with values that our community holds very dear. 

In all this my primary concern is has been for the good standing of the Royal Society as the UK’s national academy. As I am sure you understand all too well (given your recent remarks in the wake of Mr Musk’s ill-judged speech at the Tommy Robinson rally), the country, the world at large, and the very practice of science itself face severe challenges from technologies and populist politics that foment division and ignorance. In such troubled times, people look to our established institutions to have the courage to stand by long-held values of truth and decency. 

It is my sincere hope the Royal Society will demonstrate tomorrow that it is just such an institution. 

Yours faithfully, 

Stephen"
katholt.bsky.social
This is an embarrassment. What is the point of a society that cannot uphold its own values? Prestige without principles. Thankyou Stephen for continuing to point out this nonsense for what it is.
Reposted by Kat Holt
Reposted by Kat Holt
sciencevs.bsky.social
This moment from our latest episode with science writer @edyong209.bsky.social is 🔥

We asked Ed — how do we talk up the benefits of science in the face of government cuts? He told us that's the wrong approach. 🧪

Listen wherever, or watch on Spotify 👇

open.spotify.com/episode/7Evh...
Reposted by Kat Holt
scurry.bsky.social
As the @royalsociety.org council meets on 01 Oct to discuss the repudiation of its core values by one of its fellows, Elon Musk, I respectfully remind them of my proposals for actions that should help the RS recover its standing in the scientific community. occamstypewriter.org/scurry/2025/...
Conduct Unbecoming – how can the Royal Society escape its Musk box? | Reciprocal Space
occamstypewriter.org
Reposted by Kat Holt
shigellameeting.bsky.social
Come and join us in Paris 2026 to talk all about Shigella!
katholt.bsky.social
💯
kattenbarge.bsky.social
The real generational divide is people who refuse to watch a video if it could be an article versus people who refuse to read an article if it could be a video
Reposted by Kat Holt
conmeehan.bsky.social
Equitable data sharing is paramount, and this article outlines a framework for fairly attributing datasets to authors. Would be great to see this widely implicated!
It was great being part of the consortium led by @lhug.bsky.social @alexjprobst.bsky.social and others.
www.nature.com/articles/s41...
Reposted by Kat Holt
klebpapers.bsky.social
The acquisition of rmpADC can increase virulence of classical Klebsiella pneumoniae in the absence of other hypervirulence-associated genes
https://doi.org/10.1101/2025.09.20.677538
Reposted by Kat Holt
ecdc.europa.eu
The Call for Applications for #ECDCFellowship Programme #Cohort2026 is now open!

Are you passionate about #FieldEpidemiology or #PublicHealth Microbiology, and driven to investigate emerging public health threats? Ready to take your expertise to the next level?
Call for application for ECDC Fellowship Programme EPIET and EUPHEM paths, EU-track, Cohort 2026
The goal of the ECDC fellowship programme is to develop an European network of public health epidemiologists that share concepts and methods.
bit.ly
Reposted by Kat Holt
adamjkucharski.bsky.social
I'm giving a free public talk asking 'How certain is certain enough?' at @lshtm.bsky.social on Monday 24th November at 5.30pm, as part of the Global Health Lecture Series. From epidemic response and clinical trials to online misinformation and AI, I'll look at how truth emerges – and why it falters.
How certain is certain enough? | LSHTM
When faced with a new health threat, there are three crucial questions we must consider. What is going on? What can we do about it? And how can we communicate these things effectively? This talk will
www.lshtm.ac.uk
Reposted by Kat Holt
biorxiv-genomic.bsky.social
Ciprofloxacin resistance in Klebsiella pneumoniae: phenotype prediction from genotype and global distribution of resistance determinants https://www.biorxiv.org/content/10.1101/2025.09.24.678318v1
Reposted by Kat Holt
zaminiqbal.bsky.social
Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols.
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