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Dr. Krissy Lyon

@krissylyon.bsky.social

1.3K followers 940 following 89 posts

Neuroscientist & astrocyte enthusiast | Postdoc in the Allen lab @SalkInstitute.bsky.social | NINDS K99 |@lclark.bsky.social and Harvard PiN alum | she/her

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Dr. Krissy Lyon @krissylyon.bsky.social · Nov 12

Hi Blue Sky! A reintroduction: I am a neuroscientist interested in neuron-glia interactions, astrocytes, behavior, neurodevelopment, and neurodevelopmental disorders. Currently a postdoc in the Allen lab at Salk 👩🏽‍🔬🧠 Here’s a review I wrote a couple years ago: www.frontiersin.org/journals/neu...

Frontiers | From Synapses to Circuits, Astrocytes Regulate Behavior

Astrocytes are non-neuronal cells that regulate synapses, neuronal circuits, and behavior. Astrocytes ensheath neuronal synapses to form the tripartite synap...

www.frontiersin.org

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Reposted by Dr. Krissy Lyon

Piali Sengupta @senguptalab.bsky.social · 23d

A huge shoutout to all the dedicated grants management specialists at the NIH who are working around the clock to push grants out before the Sep 30 deadline. And also to the POs responding to frantic emails.
Not an easy job under the best of circumstances and right now it's the pits.
Thank you!

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Dr. Krissy Lyon @krissylyon.bsky.social · Aug 23

Required periodic Salk Institute photo☀️

Reposted by Dr. Krissy Lyon

I-75 Scientist @flscitriguy.bsky.social · Aug 22

Postdocs applying for K99s, particularly if it's your last opportunity: DO NOT forget to include a foreign justification document if you have any sort of foreign collaboration. Your application will be withdrawn if you don't have that.

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Reposted by Dr. Krissy Lyon

Steven Sloan @sloanlab.bsky.social · Aug 21

Excited to share an important new pre-print from the lab led by incredibly talented postdoc @maureenbiologies.bsky.social, a neurotoxicologist who came to the lab with an ambitious goal of understanding the consequences of toxicant exposure in human neurodevelopment. www.biorxiv.org/content/10.1...

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Reposted by Dr. Krissy Lyon

Jeremy Berg @jeremymberg.bsky.social · Aug 18

Several people have suggested that I compile my emails to Bhattacharya and I am delighted to do so.

Announcing the first cut of "Fifty Shades of 'Jay'

jeremymberg.github.io/jeremyberg.g...

This contains just the first few exchanges. I will be adding more as time permits.

A cover labeled "Fifty Shades of 'Jay' by Jeremy M Berg

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Reposted by Dr. Krissy Lyon

Ardem Patapoutian @ardemp.bskyverified.social · Aug 13

Over 20 years after Julius’s lab and mine cloned TRPM8, it is rewarding to see this science helping patients. The TRPM8 agonist Tryptyr treats dry eye by increasing tear production. A reminder that NIH-funded curiosity-driven research translates to medicines.
tryptyr.myalcon.com?gad_source=1...

TRYPTYR (acoltremon ophthalmic solution) 0.003% eye drops | Alcon US

TRYPTYR is a prescription eye drop used for the treatment of the signs and symptoms of dry eye disease. See prescribing information, how to save, and more.

tryptyr.myalcon.com

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Reposted by Dr. Krissy Lyon

The Transmitter @thetransmitter.bsky.social · Aug 13

FlyBase, a Drosophila database, will lose a third of its team in early October because the Harvard grant that covered the employees’ salaries was canceled. Scientists warn that losing FlyBase could devastate fly research.

By @claudia-lopez.bsky.social

www.thetransmitter.org/community/ha...

Harvard University lays off fly database team

The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.

www.thetransmitter.org

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Reposted by Dr. Krissy Lyon

Jeremy Berg @jeremymberg.bsky.social · Aug 13

Update on NIH funding through July (August 1 budget start dates)

Non-competitive renewal awards by month for fiscal year 2025

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$A bar graph of the fraction of NIH non-competitive renewal awards received by month showing that fewer awards that expected to being given.$

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Dr. Krissy Lyon @krissylyon.bsky.social · Aug 13

Thanks Monica!!

Dr. Krissy Lyon @krissylyon.bsky.social · Aug 13

Yes that would be great! Congrats on your new position - very happy for you!

Dr. Krissy Lyon @krissylyon.bsky.social · Aug 12

Thank you Laura!

Dr. Krissy Lyon @krissylyon.bsky.social · Aug 12

Thank you Kevin!

Dr. Krissy Lyon @krissylyon.bsky.social · Aug 12

Thanks Wendy!

Dr. Krissy Lyon @krissylyon.bsky.social · Aug 12

Excited to have received the NOA for my K99 Pathway to Independence award on astrocytes in neurodevelopmental disorders! I am so grateful for my PI Nicola Allen, and all my mentors, letter writers, and collaborators.

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Dr. Krissy Lyon @krissylyon.bsky.social · Jul 29

Cool astrocyte paper!

Astrocyte specification in the mouse septum is shaped by both developmental origin and local signals - Nature Neuroscience

The relative contribution of intrinsic and extrinsic factors to astrocyte heterogeneity is unknown. Using heterotropic transplantation of septal astrocytes with distinct lineage origins, we show that ...

www.nature.com

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Reposted by Dr. Krissy Lyon

The Transmitter @thetransmitter.bsky.social · Jul 16

To identify fundamental neuroscientific principles that generalize across species, systems and circuits, neuroscientists must embrace an evolutionary perspective, argue Karl Farrow and @katjareinhard.bsky.social.

#neuroskyence

www.thetransmitter.org/systems-neur...

Systems and circuit neuroscience need an evolutionary perspective

To identify fundamental neuroscientific principles that generalize across species, neuroscientists must frame their research through an evolutionary lens.

www.thetransmitter.org

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Reposted by Dr. Krissy Lyon

Bita Moghaddam @bita137.bsky.social · Jul 11

don't be fooled that this NIH effort is only about NOFO - listen to minute 21-22 "they are working tirelessly" to "phase out" "existing" funding www.youtube.com/watch?v=iSvk...

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Dr. Krissy Lyon @krissylyon.bsky.social · Jul 10

Congratulations to all the new awardees!! Happy to see this program ongoing!

Burroughs Wellcome Fund @bwfund.bsky.social · Jul 9

BWF is proud to announce the 2025 recipients of its Postdoctoral Diversity Enrichment Program (PDEP), which provides critical support to postdoctoral researchers pursuing careers in biomedical and medical research. www.bwfund.org/news/bwf-ann... #bwfpdep

BWF Announces 2025 Postdoctoral Diversity Enrichment Program Recipients - Burroughs Wellcome Fund

Research Triangle Park, N.C. — The Burroughs Wellcome Fund (BWF) is proud to announce the 2025 recipients of its Postdoctoral Diversity Enrichment Program (PDEP), which provides critical support to…

www.bwfund.org

Reposted by Dr. Krissy Lyon

Alexander Harris @dralexharris.bsky.social · Jul 8

In this entire 4.5 hour video from the FDA and NIH about reducing animal models, I didn't hear any discussion about conducting research developing new treatments for mental health disorders with behavioral symptoms

Alexander Harris @dralexharris.bsky.social · Jul 8

At 2:38:55 of this video is when the NIH component of the workshop begins. 2:49:11 is where the announcement of no new NIH funding of proposals relying exclusively on animals youtube.com/live/vz1uF42...

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Reposted by Dr. Krissy Lyon

Kelsey Tyssowski @kelseytea.bsky.social · Jul 7

I'll be presenting at this science fair: I've done many a poster presentation, but never one quite like this!

Dr. Rabbithole @drrabbithole.bsky.social · Jul 6

A science fair of cancelled grants. The research that will be represented at this event (Tuesday) ranges from neuroscience, to astrophysics, to STEM education. The awarding agencies of the now-canceled grants include the EPA, DHS, NIH, NSF, USAID, and DOD. Open to the public.

Congressional Event: A Science Fair of Canceled Grants

The Things We’ll Never Know: A Science Fair of Canceled Grants.

nasawatch.com

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Reposted by Dr. Krissy Lyon

Dr. Lucky Tran @luckytran.com · Jul 8

BREAKING: Scientists are staging a “science fair” in the lobby of a Congressional building to tell elected officials about the critical knowledge the US will lose because their research grants have been canceled.

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Reposted by Dr. Krissy Lyon

Jeni Kubota @jenikubota.bsky.social · Jun 18

It would be great if other journals did this

Association for Psychological Science @psychscience.bsky.social · Jun 18

Call for Submissions! Behavioral Medicine: Special Issue on Terminated Grants.

Submit by June 30 at 5PM ET. Learn more here: acrobat.adobe.com/id/urn:aaid:...

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Dr. Krissy Lyon @krissylyon.bsky.social · Jun 14

Blocks and blocks of San Diegans showing up to protest, chanting ‘This is what democracy looks like!’ 🇺🇸

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Reposted by Dr. Krissy Lyon

Indivisible ❌👑 @indivisible.org · Jun 14

Stay classy, San Diego. #NoKings

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Reposted by Dr. Krissy Lyon

Mari Sosa @marisosa.bsky.social · Jun 12

It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵

www.nature.com/articles/s41...

A flexible hippocampal population code for experience relative to reward - Nature Neuroscience

Sosa et al. find that hippocampal neural activity in mice encodes both environmental location and experience relative to rewards, spanning distances far from reward, through parallel and flexible popu...

www.nature.com

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