Lindsay K Pino
@lindsaykpino.com
#massspectrometry, #proteomics, and #bioinformatics | hiking and dogs | co-founder & CTO @talusbio | opinions my own
At least my peptides dried down nicely
November 29, 2025 at 10:53 PM
At least my peptides dried down nicely
Well, I'm ordering more lines, but wow this was ... not what I was prepared for! Although I might be able to frit and pack my own traps, and score/trim silica, and crimp my own fittings, it looks like we're at an impasse until more lines get delivered.
November 29, 2025 at 10:47 PM
Well, I'm ordering more lines, but wow this was ... not what I was prepared for! Although I might be able to frit and pack my own traps, and score/trim silica, and crimp my own fittings, it looks like we're at an impasse until more lines get delivered.
I always pictured these when I got offered "certificates" for reviewing
November 29, 2025 at 10:27 PM
I always pictured these when I got offered "certificates" for reviewing
Now the line on the OTHER side of the trap is broken. I already used our last replacement line on the right hand side so my journey might be ending here.
November 29, 2025 at 10:07 PM
Now the line on the OTHER side of the trap is broken. I already used our last replacement line on the right hand side so my journey might be ending here.
Leak test time. BACK IN MY DAY we didn't have fancy scripts for leak tests. We used a twisted up kim wipe shoved into the connections to look for leaks.
November 29, 2025 at 8:41 PM
Leak test time. BACK IN MY DAY we didn't have fancy scripts for leak tests. We used a twisted up kim wipe shoved into the connections to look for leaks.
RIGHT?! It's hollow inside and the trap is a cylinder like this that drops into the metal piece and gets held in place by the viper fittings on either side
November 29, 2025 at 8:34 PM
RIGHT?! It's hollow inside and the trap is a cylinder like this that drops into the metal piece and gets held in place by the viper fittings on either side
Today on "PI Back In The Lab After A Year", Lindsay tries to change the trap on a Neo Vanquish. Step 1: slack mass spec team and sheepishly confirm that this part is somehow the trap
November 29, 2025 at 8:21 PM
Today on "PI Back In The Lab After A Year", Lindsay tries to change the trap on a Neo Vanquish. Step 1: slack mass spec team and sheepishly confirm that this part is somehow the trap
Watch out, it's that time of year again. The PI is getting back into the lab.
November 26, 2025 at 6:52 PM
Watch out, it's that time of year again. The PI is getting back into the lab.
Upcoming talks at Human Proteome Organization! Come check out what Talus Bio has been working on over the last year, from mapping the regulome to manipulating it and modeling it, all using mass spectrometry proteomics as a driving force.
November 10, 2025 at 6:25 AM
Upcoming talks at Human Proteome Organization! Come check out what Talus Bio has been working on over the last year, from mapping the regulome to manipulating it and modeling it, all using mass spectrometry proteomics as a driving force.
Update: it did, indeed, snow at HUPO.
November 9, 2025 at 10:23 PM
Update: it did, indeed, snow at HUPO.
There is, admittedly, a cool collection of mass spec parts that @bushlab.bsky.social gathered together
November 4, 2025 at 7:54 PM
There is, admittedly, a cool collection of mass spec parts that @bushlab.bsky.social gathered together
Day 2, amazing analogy by Evan Williams @berkeleychemistry.bsky.social for charge detection
November 4, 2025 at 7:02 PM
Day 2, amazing analogy by Evan Williams @berkeleychemistry.bsky.social for charge detection
I have to say, there's been a very disappointing lack of mass spec gore so far. How can you have a whole lecture about turbo pumps and no "rest in pieces" graveyard pics??
I'll go first. RIP turbo from @maccoss.bsky.social (believe it was a QE-HF).
I'll go first. RIP turbo from @maccoss.bsky.social (believe it was a QE-HF).
November 3, 2025 at 6:25 PM
I have to say, there's been a very disappointing lack of mass spec gore so far. How can you have a whole lecture about turbo pumps and no "rest in pieces" graveyard pics??
I'll go first. RIP turbo from @maccoss.bsky.social (believe it was a QE-HF).
I'll go first. RIP turbo from @maccoss.bsky.social (believe it was a QE-HF).
Kicking us off is @maccoss.bsky.social , melting my mind at 8am with this observation that LC-MS is really a lossless single molecule compression method at its core.
October 16, 2025 at 3:34 PM
Kicking us off is @maccoss.bsky.social , melting my mind at 8am with this observation that LC-MS is really a lossless single molecule compression method at its core.
Wrapping up the skyline.ms virtual workshop on #MassSpectrometry #proteomics with Advanced Proteomics: data independent acquisition today, post-translational modifications tomorrow. @juank1892.bsky.social @arianashannon.bsky.social @miriamabele.bsky.social (anybody else on bsky?) 🖥️🧬🧪
October 16, 2025 at 3:22 PM
Wrapping up the skyline.ms virtual workshop on #MassSpectrometry #proteomics with Advanced Proteomics: data independent acquisition today, post-translational modifications tomorrow. @juank1892.bsky.social @arianashannon.bsky.social @miriamabele.bsky.social (anybody else on bsky?) 🖥️🧬🧪
Skyline Online Session 3 just kicked off. Ariana Shannon of @mayoclinic.org organized a great 2-day introduction to the skyline.ms software for quantitative mass spectrometry proteomics. 💻🧬 #TeamMassSpec #proteomics
October 14, 2025 at 3:14 PM
Skyline Online Session 3 just kicked off. Ariana Shannon of @mayoclinic.org organized a great 2-day introduction to the skyline.ms software for quantitative mass spectrometry proteomics. 💻🧬 #TeamMassSpec #proteomics
This is actually much longer than I expected. But at least it's not in Latin.
October 14, 2025 at 3:11 PM
This is actually much longer than I expected. But at least it's not in Latin.
On my way back to Seattle after my first Forbeck Forum at the beautiful Lake Geneva. Really interesting conference format: <20 people, 45 minutes to "present", maximum TWO slides. Lots of good discussion and I learned a ton -- and probably got myself into even more work/collaborations 😂
October 8, 2025 at 2:06 PM
On my way back to Seattle after my first Forbeck Forum at the beautiful Lake Geneva. Really interesting conference format: <20 people, 45 minutes to "present", maximum TWO slides. Lots of good discussion and I learned a ton -- and probably got myself into even more work/collaborations 😂
My goal to read more for pleasure this year is going well, largely thanks to scifi/fantasy/YA page-turners, but sometimes (okay okay rarely) I read non-fiction too
www.goodreads.com/book/show/41...
www.goodreads.com/book/show/41...
September 23, 2025 at 1:44 AM
My goal to read more for pleasure this year is going well, largely thanks to scifi/fantasy/YA page-turners, but sometimes (okay okay rarely) I read non-fiction too
www.goodreads.com/book/show/41...
www.goodreads.com/book/show/41...
It was wonderful to meet old and new collaborators in person to catch up on ongoing projects and some exciting new work that's getting kicked off with the Tech Access Program
www.talus.bio/news/talus-b...
www.talus.bio/news/talus-b...
August 29, 2025 at 1:56 PM
It was wonderful to meet old and new collaborators in person to catch up on ongoing projects and some exciting new work that's getting kicked off with the Tech Access Program
www.talus.bio/news/talus-b...
www.talus.bio/news/talus-b...
Congrats to @mannlab.bsky.social on election to the National Academy of Sciences! www.nasonline.org/news/2025-na...
And to @kusterlab.bsky.social for successfully exiting OmicsScouts www.prnewswire.com/news-release...
And @hecklab.bsky.social on launching a newco. www.abvion.bio/team
And to @kusterlab.bsky.social for successfully exiting OmicsScouts www.prnewswire.com/news-release...
And @hecklab.bsky.social on launching a newco. www.abvion.bio/team
August 29, 2025 at 1:54 PM
Congrats to @mannlab.bsky.social on election to the National Academy of Sciences! www.nasonline.org/news/2025-na...
And to @kusterlab.bsky.social for successfully exiting OmicsScouts www.prnewswire.com/news-release...
And @hecklab.bsky.social on launching a newco. www.abvion.bio/team
And to @kusterlab.bsky.social for successfully exiting OmicsScouts www.prnewswire.com/news-release...
And @hecklab.bsky.social on launching a newco. www.abvion.bio/team
I had meant to live-post more of my Boston trip but clearly it was a whirlwind 😂
Excellent conversation with amazing company. And of course THE WHEEL made an appearance! @andreagut95.bsky.social @juliar2bs.bsky.social
Excellent conversation with amazing company. And of course THE WHEEL made an appearance! @andreagut95.bsky.social @juliar2bs.bsky.social
August 29, 2025 at 1:50 PM
I had meant to live-post more of my Boston trip but clearly it was a whirlwind 😂
Excellent conversation with amazing company. And of course THE WHEEL made an appearance! @andreagut95.bsky.social @juliar2bs.bsky.social
Excellent conversation with amazing company. And of course THE WHEEL made an appearance! @andreagut95.bsky.social @juliar2bs.bsky.social
We had the kangaroos in the 90s! They rebooted them or something recently, changed the cookies and reformulated the childhood recipe and it doesn't taste the same anymore. Too many emulsifiers or something.
August 4, 2025 at 2:52 PM
We had the kangaroos in the 90s! They rebooted them or something recently, changed the cookies and reformulated the childhood recipe and it doesn't taste the same anymore. Too many emulsifiers or something.