Recruitment to cancer #ClinicalTrials is often highly selective, and some people face barriers to participation.

To prevent these issues from limiting our progress against the disease, we're working to bridge the gap between clinical trials and real-world practice ⬇️

www.icr.ac.uk/research-and...

There has been a lot of debate recently about the promise of real world data - the routine (observational) data collected on patients eg  treatments received, clinical outcomes etc – for estimating treatment effects. But can they deliver? 1/9
#MethodologyMonday #123

I wrote some stuff about single-arm trials

simonelgato.github.io/2025/06/10/s...

The updated SPIRIT 2025 statement enhances randomized trial protocols, adding clarity and transparency for better research practices.

by Chan AW, Boutron I (...) Hróbjartsson A et 36 al. in JAMA #MedSky

👉 get more here

📖 read the article:

Scoping reviews & their role in identifying research priorities

H. Khalil, R. Jia, E.B. Moraes, Z. Munn, L. Alexander, MDJ Peters, A. Asran, C.M. Godfrey, @andreatricco.bsky.social, @daniellepollock.bsky.social, C. Evans

www.jclinepi.com/article/S089...

That sounds like a perfect way to kick off the day! A cup of coffee always sets the right tone. ☕😊

#nicedogs #coffeedogs #nicedaywithdog

Great talk Darren, thanks again. Lots of tips for us to action! @andrewdullea.bsky.social

Really looking forward to your talk Darren!

@vickiye.bsky.social @mdimairo.bsky.social

Hello Bluesky 👋 #ThePeoplesReview is a citizen science project inviting the public to get involved in a systematic review about health!

Check out this video for more info about what The People’s Review is all about - youtu.be/4OoIjJY0tbE

Yet more evidence that including a librarian in an evidence synthesis project improves quality and reproducibility pmc.ncbi.nlm.nih.gov/articles/PMC... #medlibs #systematicreviews

How should we describe randomisation to people when recruiting them to a trial? Simple little study, but useful for us all to think about how we do this - it is not just understanding that is important, we also need to consider the acceptability of the language we use.

rdcu.be/dZGg1

Please add me Jo. Work in evidence synthesis & HTA. Thanks!

Reflection paper on establishing efficacy based on single-arm trials submitted as pivotal evidence in a marketing authorisation.

www.ema.europa.eu/en/establish...

Can I make another public service announcement, akin to the "don't ask your students to do systematic or scoping review but rather assign targeted activities that could help them perform one in the future?"

A thread!