Madhura Nijsure, PhD
@madhura0327.bsky.social
110 followers 140 following 21 posts
Postdoc in @cjrosenlab.bsky.social at MaineHealth 🦴🔬
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madhura0327.bsky.social
Very excited to see my PhD story out in @science.org Science Advances!

We followed up on the preprint with experiments on two additional groups that added a lot of nuance to the effect of BMP4 on post-fracture periosteal expansion!

🦴🔬

www.science.org/doi/10.1126/...
YAP regulates transcriptional programs for layer-specific periosteal expansion during fracture repair
YAP regulates gene programs that promote layer-specific periosteal expansion during early bone fracture repair.
www.science.org
Reposted by Madhura Nijsure, PhD
katecavanaugh.bsky.social
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
Reposted by Madhura Nijsure, PhD
hugheslabpenn.bsky.social
Aria Huang's @azyhuang.bsky.social paper is out on beautiful embryonic kidney 3D cultures that branch properly and enable live defect analysis. She also finds intriguing effects of adhesion and stiffness on explant size, shape, and nephron formation - boundary conditions matter!

rdcu.be/eBSUK
madhura0327.bsky.social
Oh my gosh, so excited to read this! The imaging looks fantastic! ❤️
Reposted by Madhura Nijsure, PhD
isfrfractures.bsky.social
🚨Reminder to stay hydrated 🐳as you scramble to put together your #ORS2026 abstracts! 🦴🩻

Abstracts are due on Monday, August 25th! www.ors.org/2026abstracts/

Be sure to check out the new abstract requirements this year!

#bonehealing #fracturerepair #bone

@orssociety.bsky.social
Call for Abstracts - ORS
For the 2026 abstract submission you will be using your ORS login information. If you do not have an ORS username, you will have the opportunity to create one. Submit Your Abstracts Abstract Submissi...
www.ors.org
Reposted by Madhura Nijsure, PhD
cjrosenlab.bsky.social
Proof that beach days are good for #bones!
madhura0327.bsky.social
Shout out to @cpane94.bsky.social @eseidlscience.bsky.social @gkotsaris90.bsky.social @amilangscience.bsky.social and the other co-authors not on 🦋! I wish we could cite as Madhura & besties, rather than et al! 😊👯👯‍♂️
madhura0327.bsky.social
I’m incredibly grateful for the collaborative environment at Penn Medicine/McKay and in @jboerckel.bsky.social’s lab that made this work possible! Special shoutout to @ryanet.bsky.social for encouraging me to run RNAScope to figure out who is making BMP4! 🕵️
madhura0327.bsky.social
Very excited to see my PhD story out in @science.org Science Advances!

We followed up on the preprint with experiments on two additional groups that added a lot of nuance to the effect of BMP4 on post-fracture periosteal expansion!

🦴🔬

www.science.org/doi/10.1126/...
YAP regulates transcriptional programs for layer-specific periosteal expansion during fracture repair
YAP regulates gene programs that promote layer-specific periosteal expansion during early bone fracture repair.
www.science.org
madhura0327.bsky.social
I do this with eggs 😂 Ice cubes is the next level!
Reposted by Madhura Nijsure, PhD
cjrosenlab.bsky.social
We are SO excited to welcome Dr. Madhura Nijsure @madhura0327.bsky.social to the Rosen lab this week! As a postdoc, she is excited to explore how diet and nutrition influence bone health and homeostasis at the molecular level. Stay tuned for her amazing research!
Reposted by Madhura Nijsure, PhD
jboerckel.bsky.social
Out latest preprint, from @cpane94.bsky.social in the lab, is out today!

Maternal exercise rescues fetal akinesia-impaired joint and bone development.
www.biorxiv.org/content/10.1...

So excited for this one - a wonderful collab with Niamh Nowlan, supported by the US-Ireland Partnership Programme ❤️
“Supervised” maternal wheel running exercise from E13.5-E16.5 Maternal exercise induces passive movements that rescue the effects of fetal akinesia on forelimb bone and joint development.
Reposted by Madhura Nijsure, PhD
cjrosenlab.bsky.social
Congratulations to the @asbmr.bsky.social Harold M. Frost Young Investigator Award recipients! We are excited to see our own @carolynchlebek.bsky.social among the awardees 🎉 Attend the @orssociety.bsky.social Musculoskeletal Biology Workshop to hear from the awardees about their exciting research!
Reposted by Madhura Nijsure, PhD
asbmr.bsky.social
Fuller Albright Award
Joel Boerckel, Ph.D., University of Pennsylvania, United States
Reposted by Madhura Nijsure, PhD
soslowskylab.bsky.social
And BIG CONGRATS to our #TendieFriendie and #BoerckelLabBestie, Elizabeth (‪@eseidlscience.bsky.social of ‪@jboerckel.bsky.social‬ lab), who won the best poster award!
madhura0327.bsky.social
Very excited for my post-doc adventure with @cjrosenlab.bsky.social at the Maine Health Institute of Research in Portland, ME! Still looking at bones, but with a slight twist 😉❤️
madhura0327.bsky.social
Wrapping up my last day in @jboerckel.bsky.social’s lab with one last round of imaging with @gkotsaris90.bsky.social! Philly’s been home for six incredible years—full of science, laughter, and amazing friends. It’s a tough world, but the besties make it less scary. On to the next adventure ❤️
Reposted by Madhura Nijsure, PhD
cjrosenlab.bsky.social
Curious about how follicle-stimulating hormone FSH contributes to the development of osteoporosis, obesity, and cognitive decline? Check out this recent review published in @cp-trendsmolecmed.bsky.social
www.cell.com/trends/molec...
Reposted by Madhura Nijsure, PhD
cjrosenlab.bsky.social
Have you ever dreamed of isolating primary bone marrow adipocytes but were unsure of how? Check out our recent chapter in Bone Research Protocols detailing the isolation! Huge congrats to lead author, Dr. Samantha Costa! doi.org/10.1007/978-...
Reposted by Madhura Nijsure, PhD
haoyin.bsky.social
Not every organ ages the same🤠

With Age, Skull bone marrow Vasculature+HSPC Expand & ⏫ contribution to peripheral leukocyte

Skull BM expands with Pregnancy CML PTH Stroke

@bikohcello.bsky.social
@vishalmkrishnan.bsky.social
@ralfhadams.bsky.social
@nature.com 2024
www.nature.com/articles/s41...
madhura0327.bsky.social
I kind of love the idea of having an 'ideas and speculation' section! ❤️ Sure you could be wrong...but what if you're right!?
elife.bsky.social
Authors of this #DevBio study, ranked fundamental, have included an ‘Ideas and Speculation’ section 💡

They propose possible mechanistic explanations of their research on BMP4 mutations that contribute to vertebrate development.
buff.ly/SAdgQOo
illustration of proposed mechanisms above images of mouse embryos
madhura0327.bsky.social
Incredible work, Blake!! You’re crushing it! ❤️