Manuel Kleiner
@manuelkleiner.bsky.social
730 followers 200 following 42 posts
Associate Professor, Microbiomes and Complex Microbial Communities, North Carolina State University Microbiology, Host-Microbe Interactions, Microbial Ecophysiology, Proteomics and Metaproteomics https://kleinerlab.cals.ncsu.edu/
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Reposted by Manuel Kleiner
comingupcharlie.bsky.social
This is gaining traction in anti-COVID vax circles but none of them have clocked that it comes from a dataset spanning 2000-2020. The shots are so powerful they transcend time.
manuelkleiner.bsky.social
Plant root exudates are important in biotic and abiotic interactions that are critical for plant health. the focus so far is mostly on small molecules. Proteins are an understudied, abundant component of root exudates. Time to explore! www.sciencedirect.com/science/arti...
Root-secreted proteins: an underexplored component of root exudates
Proteins are integral components of root exudates that mediate plant–microbe interactions, nutrient mobilization, and stress responses. Despite their …
www.sciencedirect.com
Reposted by Manuel Kleiner
Attention plant proteomics specialists: We are looking for a Head of our new Proteomics Unit at our international and dynamic Max Planck Institute of Molecular Plant Physiology. @mpi-mp-potsdam.bsky.social Applications are welcome until 30. Sept 2025: jobs.mpimp-golm.mpg.de/jobposting/8...
Head of Service Unit Proteomics
jobs.mpimp-golm.mpg.de
manuelkleiner.bsky.social
The article has also a table with more in depth resources on various aspects of experimental design for more advance design needs.
manuelkleiner.bsky.social
I am really excited to see this article on basic experimental design principles published. Definitely will be mandatory reading for incoming graduate students in my lab. Maggie Wagner who led this article did an amazing job with the illustrations of basic principles www.nature.com/articles/s41...
How thoughtful experimental design can empower biologists in the omics era - Nature Communications
Here, the authors discuss principles of experimental design that are relevant for all biology research, along with special considerations for projects using -omics approaches, highlighting common expe...
www.nature.com
manuelkleiner.bsky.social
Congratulations to Ayesha Awan in my lab to her first, first author paper from her PhD getting published.
Publishing it as a pre-print really helped as it took a whole year from first submission to publication
pubs.rsc.org/en/Content/A...
Reposted by Manuel Kleiner
evolvedbiofilm.bsky.social
July issue of @cp-trendsmicrobiol.bsky.social is now online, with our review by @xinmingxu.bsky.social @neftalyl.bsky.social on Composing a microbial symphony and a matching cover illustration by @lizahaart.bsky.social

#SynCom #PlantMicrobiome #MicrobiomeEcology at #LeidenBiology
Reposted by Manuel Kleiner
beatekraft.bsky.social
Two Postdoc Opportunities in Environmental Microbiology!

Join us and work on microbial key players exposed to oxygen depletion.

Please share widely!
Deadline: 25 July

More information can be found here:
tinyurl.com/4kwzzt6p
Two postdoc positions on the ecology and physiology of microbial key players exposed to oxygen depletion
Application deadline: 25 July 2025 at 23:59 hours local Danish time
tinyurl.com
Reposted by Manuel Kleiner
sarahmackattack.bsky.social
I'm working on a quickstart guide for people who want to plant native plants, but don't know all the things to consider when choosing plants.

I think this is inherently challenging due to the absolute mountain of caveats that goes into doing this properly.

However.

Here's where we're at.
An infographic labeled "Should I buy this plant? a bug-approved guide" 

It takes you through the following line of questioning "1. Is it native: Look at the name of the plant here and see if it's native to your region. If no, Is it good at feeding bugs? Some non-native make lots of nectar. You can google if unsure. If yes, Are there better options available? if yes, don't buy it. If no, buy it. Ok, let's go back to the top. If it IS native, is it a cultivar? Does it have a goofy name like "Daisies jubilee" or "Pink Flamingo Hibiscus" It's a cultivar. If it's a cultivar, it'll send you to are there better options available? If it's not, on to question 3, which is "Was it grown with pesticides? This can be hard to tell. Check with the origin nursery. If yes, are there better options. If no, "Hell yeah". 

There are little flowers on a bunch of the boxes. The Hell Yeah box has a swallowtail butterfly with sunglasses giving a thumbs up. The no has a sassy bee looking over its sunglasses at you judgementally with its hand on its hips.

On the bottom is says "Need help? Text questions to 9-RUNG-SQUID
Reposted by Manuel Kleiner
cashwood.proteaglyco.com
One of the most misleading specifications I've seen from a vendor this year.

The Excedion Pro is able to achieve the 70 Hz (2x faster than the 480) under defined conditions. Specifically, a brand new scan option to run at 3700 res at 200 m/z.

For those used to ppm, that's a 276 ppm mass error.
Reposted by Manuel Kleiner
jeanmichelane.bsky.social
Great review from @garciakevin.bsky.social‬ -> Mutualistic Relationships Between Roots and Soil Microbes Facilitate Plant Potassium Acquisition
Mutualistic Relationships Between Roots and Soil Microbes Facilitate Plant Potassium Acquisition
Soil supports diverse life forms and ecosystems through complex interactions among its components, many of which remain poorly understood. Potassium (K) is a vital macronutrient that plays an essential role in plant growth, enzymatic activities, and stress tolerance, but its bioavailability in soils is limited due to complexation in minerals, such as muscovite, biotite, and feldspars. Therefore, only a small fraction is in exchangeable, plant-accessible form. While K fertilizers are commonly used in agriculture and agroforestry to address K deficiencies, the contributions of soil microbial communities to K solubilization and plant acquisition are increasingly recognized. Soil microbes, including K-solubilizing fungi and bacteria, enhance nutrient availability by decomposing soil components, facilitating K release and plant uptake. Despite early recognition of microbial K solubilization in the late nineteenth century, the role of microbes in supporting plant K acquisition remains underexplored, particularly in natural and agro-ecosystems. This chapter reviews current knowledge on plant K uptake mediated by soil microbes, including endophytic and K-solubilizing fungi, bacteria, and mycorrhizal fungi, to highlight their potential for improving soil K cycling, plant K-use-efficiency, and sustainable agricultural practices.
link.springer.com
Reposted by Manuel Kleiner
drandrewburgess.bsky.social
Love today’s #xkcd comic on
#MassSpec
🤣
BEFORE THE BATHROOM SCALE WAS INVENTED, THE ONLY
WAY TO WEIGH PEOPLE WAS MASS SPECTROMETRY.
Reposted by Manuel Kleiner
nesvilab.bsky.social
Exciting news: We have released #FragPipe 23, and it's one of our biggest updates ever. Windows installer, support for TMT on Astral and timsTOF, TMT35, PTM site reports for DIA, improved Astral data handling in #MSFragger, improved diaTracer for diaPASEF data, better Skyline integration, and more!
Reposted by Manuel Kleiner
campylobacterlab.bsky.social
Hey y'all! My department is conducting a search for an assistant or associate professor in bacteriology. It's pretty broadly defined. If you know anyone who's looking for a great department that does awesome science - please send them our way! You can DM me with any questions you have 😀
Reposted by Manuel Kleiner
Reposted by Manuel Kleiner
astrobiomike.org
This is important work for the exciting next stage of metagenomics #MicroSky
Reposted by Manuel Kleiner
markowenmartin.bsky.social
It's Thursday! #MattersMicrobial episode 87 is up. This time, Dr. Manuel Kleiner joins the #QualityQuorum to chat about how dietary protein interacts with the microbiome. Please share the #GoodMicrobialWord? @microbetv.bsky.social @asm.org @manuelkleiner.bsky.social

youtu.be/a4DmJ3Qvlnc?...
Reposted by Manuel Kleiner
markowenmartin.bsky.social
I had a nice time recording a podcast session with @manuelkleiner.bsky.social today for next week's #MattersMicrobial. I learned so much about how the microbiome responds to dietary changes. Plus thoughts about mucus farming by microbiota... Such fun! Heard about VIM @nicoledubilier.bsky.social!
Reposted by Manuel Kleiner
quadraminstitute.bsky.social
🆕 Vacancy! We’re looking for a Senior Bioinformatics Engineer to join the Core Bioinformatics team and define the bioinformatics support behind the institute’s research into gut health, microbiology and food 🧬

💷 £44,500 to £55,000
🗓️ Apply by 19 May 2025
➡️ buff.ly/zFQodP6
A social card with a digital illustration of DNA strands and the text "Senior Bioinfomatic Engineer" to maintain our infrastructure in particular the Galaxy Project server and OpenNebula Cloud