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Reposted by David Margolis

DrDinD.bsky.social @drdind.bsky.social · 1d

The Nobel Prizes, 5 of 6 having so far gone to US based scientists, are a reminder of why we must stand up for science against this horrid administration. Here are some great Scientist Activists to follow.

go.bsky.app/14W5Rdk

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David Margolis @margolislab.bsky.social · 1d

👀“experience of a punished outcome generates a BLA representation that is selectively replayed when animals subsequently abort choice of the large/risky reward option.”
⚡️“… risk leads to the incorporation of newly encoding BLA neurons into the pre-choice representation”

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 1d

Risk reshapes amygdala representation of choice https://www.biorxiv.org/content/10.1101/2025.10.06.680813v1

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David Margolis @margolislab.bsky.social · 1d

A big step in the work of postdoc Arlene George. Nice work Arlene!!

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 1d

Neuropathic pain drives time-dependent reorganization of corticostriatal circuits https://www.biorxiv.org/content/10.1101/2025.10.07.680927v1

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Reposted by David Margolis

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 1d

Controlled Delivery of a Neurotrophic Factor in the Adult Mouse Brain Using Engineered Microglia https://www.biorxiv.org/content/10.1101/2025.10.06.680702v1

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Reposted by David Margolis

Gregg Gonsalves @gregggonsalves.bsky.social · 18d

So many academics are on HB-1 visas. This is another attack by #RussellVought on universities and scientific research. Stop telling me anything this administration does is in good faith or with any sort of policy goal except destruction.

Justin Wolfers @justinwolfers.bsky.social · 18d

Critical part of the President's new $100,000 charge for H1-B visas: The Administration can also offer a $100,000 discount to any person, company, or industry that it wants. Replacing rules with arbitrary discretion.

Want visas? You know who to call and who to flatter.

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Reposted by David Margolis

Ann Kennedy @antihebbiann.bsky.social · 20d

And we are live!

Excited to announce the 2025 Multi-Agent Behavior Challenge on cross-lab supervised action recognition in mice 🐁🐀🖱️

Running on Kaggle until December 15th, with a $50,000 prize pool going to the top five submissions!

www.kaggle.com/competitions...

https://www.kaggle.com/competitions/MABe-mouse-behavior-detection

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Reposted by David Margolis

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 22d

Stimulus-Dependent Dopamine Dynamics from LocusCoeruleus Axons https://www.biorxiv.org/content/10.1101/2025.09.15.676390v1

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Reposted by David Margolis

Prof Phoebe Barnard @phoebebarnard.bsky.social · 28d

Whether or not you are a US scientist, you’ll know that this US administration’s reckless ideology endangers the entire globe - the trajectory of human civilization and all life on Earth. Scientists please sign.

AGU (American Geophysical Union) @agu.org · 28d

The EPA’s endangerment finding is under threat. This peer-reviewed climate science is essential to protecting public health & regulating greenhouse gases.

Scientists: add your name to AGU’s letter defending the science before 15 Sept.

Sign on ➡️ buff.ly/yuUbZo4

#ClimateScience #ScienceIsEssential

Sign on to Defend EPA Peer-Reviewed Climate Science | WorkForms

From requests, feedback to data collection and more. Turn your insights into action with customizable WorkForms.

lite.spr.ly

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David Margolis @margolislab.bsky.social · Aug 29

Glorious whiskers too

Patrick Vallely @pjvphotography.bsky.social · Aug 28

"Pat, why do you carry that ridiculous 600mm lens on long hikes?"

Buddy, I can see mountains reflected in the eyes of a trailside pika.

Tighter crop of the same pika, focusing on its head.

An even tighter crop, focusing more on the pika's eye.

An extremely tight crop of the pika's eye, emphasizing their reflection of an early morning mountain scene.

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Reposted by David Margolis

Claire O'Callaghan @claireocallaghan.bsky.social · Aug 29

Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level).

If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...

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Reposted by David Margolis

Robyn St. Laurent @robynstlaurent.bsky.social · Aug 14

All donations goes straight to the project (+10% bonus donation will be added if you use my referral link above)
www.researchhub.com/fund/4309/ac...

Accelerating What We Know About OCD: From Genes to Mice t...

Accelerating What We Know About OCD: From Genes to Mice to Bet...

www.researchhub.com

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David Margolis @margolislab.bsky.social · Aug 14

‘ In response to a request for comment, Zhu told us, “I have retired and I am in Greenland. I do not have to talk to you.” ‘

Retraction Watch @retractionwatch.com · Aug 13

Genomics pioneer George Church earns first retraction for anti-aging gene therapy paper

@averyorrall.bsky.social reports

Genomics pioneer George Church earns first retraction for anti-aging gene therapy paper

George Church A paper coauthored by geneticist George Church has been retracted following an internal review at a university where several coauthors are based. The article appeared in the Proceedin…

retractionwatch.com

Reposted by David Margolis

David Corn @davidcorn.bsky.social · Aug 11

The biggest violent crime spree in Washington, DC, happened on January 6, 2021, and Trump pardoned hundreds of violent felons who were part of that.

Judd Legum @juddlegum.bsky.social · Aug 11

TRUMP: Violent crime in DC is spiraling out of control so I'm deploying the National Guard

REALITY:

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Reposted by David Margolis

Mark Lemley @marklemley.bsky.social · Aug 8

All scientific grant funding must now be approved by a political appointee and "demonstrably advance the President's policy priorities."

I wonder where innovation will happen in the future? It won't be in the US

arstechnica.com/science/2025...

New executive order puts all grants under political control

All new funding on hold until Trump administration can cancel any previously funded grants.

arstechnica.com

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Reposted by David Margolis

Beth Kingsley @ejkdc.bsky.social · Aug 9

I really worry about the world the next generation or the one after it will be growing up to live in.

Mark Lemley @marklemley.bsky.social · Aug 8

All scientific grant funding must now be approved by a political appointee and "demonstrably advance the President's policy priorities."

I wonder where innovation will happen in the future? It won't be in the US

arstechnica.com/science/2025...

New executive order puts all grants under political control

All new funding on hold until Trump administration can cancel any previously funded grants.

arstechnica.com

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David Margolis @margolislab.bsky.social · Aug 9

Congrats!

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Reposted by David Margolis

Bratislav Misic @misicbata.bsky.social · Aug 4

Integrating and interpreting brain maps | doi.org/10.1016/j.ti...

Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️

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Reposted by David Margolis

Mark Peifer (He, him) @peiferlabunc.bsky.social · Aug 4

While many institutions are capitulating to Trump, my favorite scientific societies are fighting back. Aug 1 @ascbiology.bsky.social, @asm.org, @asbmb.bsky.social, & @faseborg.bsky.social jointly filed an expanded amicus brief with the Supreme Court in American Public Health Association v. NIH 1/n

Leading Scientific Societies File Amicus Brief With U.S. Supreme Court in Support of NIH Grant Recipients

Washington, DC – August 4, 2025 – On Friday, August 1, the American Society for Microbiology (ASM), the American Society for Biochemistry and Molecular Biology (ASBMB), the American Society for Cell Biology (ASCB), and the Federation of American Societies for Experimental Biology (FASEB) jointly filed an expanded amicus brief with the Supreme Court of the United States in American Public Health Association v. NIH. As some of the nation’s largest and most respected scientific societies, the amici submit this brief to emphasize the urgent need to safeguard federal research investments, protect early-career scientists, and uphold the integrity of the nation’s science ecosystem.

The four leading life science organizations originally filed an amicus brief in the case on May 2, urging the court to find recent executive actions that led to the termination of NIH grants supporting early-career scientists—such as the Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) program—unlawful and to compel NIH to restore funding swiftly. MOSAIC grants support scientists from a wide range of backgrounds in transitioning to research careers. Today’s updated filing focuses specifically on the immediate and irreparable harm caused by the grant terminations and asks the Court to deny the government’s request for a stay pending approval.

The updated brief includes new evidence and perspectives drawn from peer-reviewed articles and commentary published in recent months, which underscore the devastating consequences these grant cancellations have already had across the scientific community. Together, ASBMB, ASCB, ASM, and FASEB represent more than 150,000 biological and biomedical researchers whose work drives innovation, improves public health, and fuels the U.S. economy. Their members have long supported and participated in programs like MOSAIC, w…

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Reposted by David Margolis

Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · Jul 30

It was an incredible relief last night that this particular nightmare only lasted about five hours or 0.0189 Scaramuccis.

That said, if Russ Vought can insert a footnote somewhere else that kills NIH funding, he will attempt it again. Project 2025 demands it.

Screenshot from WSJ that says Trump Administration Puts New Chokehold on Billions in Health-Research Funding
The National Institutes of Health can't award grants to outside researchers under a new...

Screenshot from WSJ that says

Trump Administration Scraps Effort to Pause
Health-Research
Funding
White House officials intervened to force budget office to reconsider health-research funding pause
By Liz Essley Whyte Follow, Nidhi Subbaraman

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David Margolis @margolislab.bsky.social · Jul 30

Let’s hope 🤞

rollcall.com/2025/07/28/r...

Republicans brush aside Trump plan to slash NIH funding - Roll Call

Despite criticism of accusations of sexual harassment, controversial research, lawmakers say a 40 percent cut at the agency is too much.

rollcall.com

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David Margolis @margolislab.bsky.social · Jul 30

James Joyce

David M. Perry @lollardfish.bsky.social · Jul 28

What was your favorite early clas NOT in your eventual major. Mine was Ethnomusicology: an introduction to folk music.

Anthrodiva La Chatte @anthrodiva.bsky.social · Jul 28

I invariably get, "Ooh anthro that was my favorite class/cool professor" from people I meet. I tend to think soms of it is our outré material, being willing to talk "taboo" subjects in a cross-cultural context.

Ironically MY favorite class was probably Geology 101...

Reposted by David Margolis

Rosa Lafer-Sousa @rosalafersousa.bsky.social · Jul 30

‼️🚨‼️ Russel Vought just locked up the entirety of the remaining extramural NIH budget for this fiscal year, and part of intramural. $15 billion. ~a third of the NIH budget. THIS IS AN ALL-OUT ASSAULT.

All $$ is iced except intramural salaries, admin expenses, and clinical center. NO MORE GRANTS.

🧪

Prasad Jallepalli, MD, PhD @prasad.bsky.social · Jul 30

“[Vought’s] footnote stipulated that the agency’s funding for the remainder of the fiscal year could only go to staff salaries and expenses, not to new grants or certain grants that are up for renewal. Most NIH-funded research is done by outside scientists at labs across the country.”

no words

Prasad Jallepalli, MD, PhD @prasad.bsky.social · Jul 30

this is it

#scisky #medsky www.wsj.com/politics/pol...

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Reposted by David Margolis

Jeremy Berg @jeremymberg.bsky.social · Jul 29

New Science story about multi-year funding and it potential catastrophic consequences

www.science.org/content/arti...

1/n

Odds of winning NIH grants plummet as new funding policy and spending delays bite

Funding multiyear grants up front will sharply cut number of investigators receiving awards

www.science.org

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Reposted by David Margolis

Katherine Brown @katherine-brown.bsky.social · Jul 29

This is a useful summary of how some major publishers are responding to the new NIH policy. We've just updated our policies at @biologists.bsky.social: @dev-journal.bsky.social @jcellsci.bsky.social and @jexpbiol.bsky.social will allow authors to deposit the accepted version with zero embargo.

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Reposted by David Margolis

Sam Gershman @gershbrain.bsky.social · Jul 29

This is unfortunate:
www.nytimes.com/2025/07/28/u...
I wrote to the president of Harvard. I hope other faculty will speak their conscience, even if it means more struggle ahead.

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