Several cross-country examinations have found larger gender differences in Western countries. More recently, it has been argued, from an evolutiona...

A study combining group decision-making tasks with fMRI shows that the brain’s dorsomedial prefrontal cortex uses basis functions, similar to those in the visual, motor and spatial domains, to re...

Mice generalize complex task structures by using neurons in the medial frontal cortex that encode progress to task goals and embed behavioural sequences.

Pharmacological interventions are a cornerstone of psychiatric practice. The taxonomies used to classify these interventions influence the treatment and interpretation of psychiatric symptoms. Disease-based classification systems (e.g., ‘antidepressant’ and ‘antipsychotic’) do not reflect the fact that psychotropic agents are used across diagnostic categories, nor account for the dimensional nature of both the psychopathology and biology of psychiatric illnesses.In this review we discuss the history of psychotropic drug taxonomies and their influence on both clinical practice and drug development.