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Mohamady El-Gaby

@melgaby.bsky.social

540 followers 230 following 39 posts

Neuroscientist curious about the mechanisms behind the mind: https://www.psy.ox.ac.uk/research/mind-mechanisms

www.psy.ox.ac.uk

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Mohamady El-Gaby @melgaby.bsky.social · Nov 25

A bit late to the Bluesky party but here’s our work showing a coordinate system for behavioural space, and an algorithm for computing behavioural sequences in the mFC: www.nature.com/articles/s41...

A cellular basis for mapping behavioural structure - Nature

Mice generalize complex task structures by using neurons in the medial frontal cortex that encode progress to task goals and embed behavioural sequences.

www.nature.com

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Mohamady El-Gaby @melgaby.bsky.social · 6d

This is elegant work!

manfredic.bsky.social @manfredic.bsky.social · 6d

I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !

With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics

Reposted by Mohamady El-Gaby

Kris Jensen @kristorpjensen.bsky.social · 14d

I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time!

www.biorxiv.org/content/10.1...

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Reposted by Mohamady El-Gaby

Thomas Luo @thomas-zhihao-luo.bsky.social · 21d

How does the brain decide? 🧠

Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc.

After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up.

rdcu.be/eGUrv

Transitions in dynamical regime and neural mode during perceptual decisions - Nature

Simultaneous recordings were made of hundreds of neurons in the rat frontal cortex and striatum, showing that decision commitment involves a rapid, coordinated transition in dynamical regime and neura...

www.nature.com

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Mohamady El-Gaby @melgaby.bsky.social · 21d

This might be one of the coldest photos taken in neuroscience history.

Reposted by Mohamady El-Gaby

Marlene Cohen @marlenecohen.bsky.social · Jan 4

New results for a new year! “Linking neural population formatting to function” describes our modern take on an old question: how can we understand the contribution of a brain area to behavior?
www.biorxiv.org/content/10.1...
🧠👩🏻‍🔬🧪🧵
#neuroskyence
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Linking neural population formatting to function

Animals capable of complex behaviors tend to have more distinct brain areas than simpler organisms, and artificial networks that perform many tasks tend to self-organize into modules (1-3). This sugge...

www.biorxiv.org

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Reposted by Mohamady El-Gaby

Deng Pan @dengpan.bsky.social · Aug 28

🚨We believe this is a major step forward in how we study hippocampus function in healthy humans.

Using novel behavioral tasks, fMRI, RL & RNN modeling, and transcranial ultrasound stimulation (TUS), we demonstrate the causal role of hippocampus in relational structure learning.

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Reposted by Mohamady El-Gaby

Mehdi Hasan @mehdirhasan.bsky.social · Aug 27

Ex-Israeli minister Ayalon: "There is no famine in Gaza."
Me: "Why does the IPC say there is a famine?"
Ayalon: "The IPC changed the criteria."
Me: "That's a lie. What criteria did they change?"
Ayalon: "They changed many criteria."

My full interview with Danny Ayalon: zeteo.com/p/danny-ayal...

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Reposted by Mohamady El-Gaby

Abhilasha Joshi, PhD @rhythmicspikes.bsky.social · Aug 25

We are still accepting applications for the #postdoc opportunity in the lab 🕵‍♀️ 🧠

More details 👇
Postdoctoral position: lnkd.in/g4TkRxpM
Research directions: lnkd.in/eV2iMKGf
Our team and philosophy: lnkd.in/eh3nnNgq

⏬

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Mohamady El-Gaby @melgaby.bsky.social · Aug 7

Can we use what we’ve learned about cognitive maps to understand social cognition, including theory of mind?
If you’re interested in answering this question then this is a fantastic postdoc opportunity with @mkwittmann.bsky.social in collaboration with @summerfieldlab.bsky.social and my lab.

Marco K Wittmann @mkwittmann.bsky.social · Aug 7

📢 Job announcement: Two (!) 3-year postdoc jobs in our lab at UCL 📢

🧠💫🔊 We are looking for postdocs interested in the abstract mechanisms underlying social cognition. Modelling, fMRI and non-invasive ultrasound, a new deep-brain stimulation method.

Please RT

www.ucl.ac.uk/work-at-ucl/...

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

www.ucl.ac.uk

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Reposted by Mohamady El-Gaby

Laurence Hunt @lhuntneuro.bsky.social · Aug 2

Our new paper is out! When navigating through an environment, how do we combine our general sense of direction with known landmark states? To explore this, @denislan.bsky.social used a task that allowed subjects (or neural networks) to choose either their next action or next state at each step.

PLOS Biology @plosbiology.org · Aug 1

How do humans navigate unfamiliar environments? @denislan.bsky.social @lhuntneuro.bsky.social @summerfieldlab.bsky.social show that humans & deep meta-learning networks combine ‘vector-based’ & ‘transition-based’ strategies for flexible navigation in similar ways @plosbiology.org 🧪 plos.io/45uSwNm

Task design and experimental set-up. Top left: underlying structure of the 8 × 8 grid, unseen by participants. Every state is represented by an image of an object, and these objects and their positions change on every trial. Top right: schematic diagram of the ‘map reading’ phase of each trial. Participants see a top–down view of the grid with objects obscured and successively click on blue squares to reveal ‘landmark’ objects at the location. After 16 clicks have been completed, a yellow square appears. Clicking on the yellow square reveals the ‘goal’ object for the trial. Bottom: schematic diagram of the navigation phase of each trial. Participants start in a random, previously unobserved location and are tasked with navigating to the ‘goal’ object they had just learnt about (displayed at the top). They can navigate in two ways. First, they could choose a direction to travel in by clicking on the corresponding arrow (highlighted yellow). This is analogous to using a ‘vector-based’ strategy. Alternatively, they could choose an adjacent state to travel to by clicking on one of the associated images (displayed in a random order; highlighted blue). This corresponds to using a ‘transition-based’ navigation strategy.

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Mohamady El-Gaby @melgaby.bsky.social · Jul 20

Aren’t you contradicting yourself a bit with “the only source is a terrorist organisation” and then journalists and NGOs repeating the claims? There are direct observers on the ground and literal peer reviewed studies corroborating these claims: e.g. www.thelancet.com/pdfs/journal...

www.thelancet.com

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Reposted by Mohamady El-Gaby

Kevin Mitchell @wiringthebrain.bsky.social · Jul 19

How long is the world going to allow this horror to go on?

Sky News @news.sky.com · Jul 19

Gaza: More than 30 people killed 'as Israeli troops open fire towards Palestinians waiting for aid'

More than 30 people have been killed after Israeli troops opened fire towards crowds of Palestinians waiting for aid, according to witnesses and hospital officials.

news.sky.com

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Reposted by Mohamady El-Gaby

Ali Mahmoodi @alimahmoodi.bsky.social · Jul 9

We have a Research Assistant position available in Rushworth Lab to help us with projects involving fMRI, TMS, and TUS. Find out more here my.corehr.com/pls/uoxrecru...

Job Details

my.corehr.com

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Mohamady El-Gaby @melgaby.bsky.social · Jul 5

“This whole generation is being targeted. They will suffer from memory problems, developmental delays … And the problem is even if nutrition becomes available later on, the damage is permanent,”

www.theguardian.com/world/2025/j...

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Reposted by Mohamady El-Gaby

Ben Kanter @beneuroscience.bsky.social · Jun 26

Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory.

🔗 www.science.org/doi/10.1126/...

Here's a quick summary of what we found 🧵👇

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Reposted by Mohamady El-Gaby

Mari Sosa @marisosa.bsky.social · Jun 12

It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵

www.nature.com/articles/s41...

A flexible hippocampal population code for experience relative to reward - Nature Neuroscience

Sosa et al. find that hippocampal neural activity in mice encodes both environmental location and experience relative to rewards, spanning distances far from reward, through parallel and flexible popu...

www.nature.com

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Reposted by Mohamady El-Gaby

Vitor Lopes dos Santos @vitorlds.bsky.social · Jun 5

I'm pleased to share our new work, “Spatio-temporal organization of network activity patterns in the hippocampus”, out in @cp-cellreports.bsky.social !
With Demi Brizee & David Dupret, we track how oscillations and spiking behaviour map onto hippocampal layers using an LFP-based embedding.

(1/13)

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Mohamady El-Gaby @melgaby.bsky.social · May 28

Completing the mouse, ANN, human trilogy of projects, here are two openings to study cognitive map deficits in human psychosis patients with the inimitable @mattnour.bsky.social
Using functional neuroimaging and planning tasks.
If you’re keen to join us then apply!

Dr Matthew Nour @mattnour.bsky.social · May 28

🚨 Job adverts LIVE! 🚨

We want to understand how the brain supports abstract cognition in psychosis, using cutting-edge neuroscience.

Non-Clinical RA:
lnkd.in/eva-Zzfj

Clinical RA:
lnkd.in/eSgdad_F

Postdoc:
lnkd.in/eid8gtbR

Oxford University
Due June 23

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Reposted by Mohamady El-Gaby

Arabs In Neuroscience (AiN) @arabsinneuro.bsky.social · May 1

It's that time of the year again... Applications are open for students and teaching assistants for Introduction to Computational Neuroscience 2025 summer school. Applications are open till May 15th. Apply now and Repost!
#ArabCompNeuro25 #neuroscience #education

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Mohamady El-Gaby @melgaby.bsky.social · May 9

This is not to be missed. You’ll spend your day trying to make RNNs psychotic. And we’ll pay you for it!

Prof Rick Adams @drrickadams.bsky.social · May 9

📢 Fantastic post doc job opportunity in my group and co-supervised by DeepMind's @mariaeckstein.bsky.social - now live! Ad here: tinyurl.com/26rafzdc - deadline May 29th.
This is part of a very exciting collaboration with @melgaby.bsky.social and Matt Nour, funded by @wellcometrust.bsky.social.

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

tinyurl.com

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Mohamady El-Gaby @melgaby.bsky.social · May 5

2 weeks to go!

Mohamady El-Gaby @melgaby.bsky.social · Apr 8

How do cognitive maps fail? And how can this help us understand/treat psychosis? My lab at @oxexppsy.bsky.social is hiring a Postdoc tinyurl.com/2p935hhz and RA tinyurl.com/3myfpb78 to answer these questions in mouse models.
Here's why you might want to join: 🧵

Mohamady El-Gaby @melgaby.bsky.social · Apr 26

“GAZA -- Israeli authorities have blocked supplies -- including food, medicine and fuel -- from entering the Gaza Strip for more than 50 days.”
abcnews.go.com/amp/Internat...

WFP delivers its last stocks of food in Gaza as malnutrition worsens, agency says

Israeli authorities have blocked supplies – including food, medicine and fuel – from entering the Gaza Strip for more than 50 days.

abcnews.go.com

Mohamady El-Gaby @melgaby.bsky.social · Apr 25

That’s great news! Congratulations Mari!

Mohamady El-Gaby @melgaby.bsky.social · Apr 19

*Me for the next 2 years*

youtu.be/yO4AvYzJZ20?...

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Mohamady El-Gaby @melgaby.bsky.social · Apr 19

The students were impressive to say the least. And yes re 2027! If at least to give @rhythmicspikes.bsky.social a chance to settle the scores ⚽️

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