LightNews LightNews
mecfsrecluse.bsky.social
@mecfsrecluse.bsky.social
86 followers 160 following 0 posts
Lawyer. ME since Oct 2000. Mostly housebound since 2014. #ME #hEDS #dysautonomia #Citrate synthase deficiency #impaired oxygen extraction #celiac #mitochondrial disease

Interested in ME research and treatment options.
Posts Replies Media Videos
Reposted
bhanlon15.bsky.social
Health Rising: “ME/CFS Autopsy Study Finds a Wrecked HPA Axis: The 2025 IACFS/ME Conference Report #3”

“.. they found almost no CRH producing neurons in the ME/CFS patients. That suggested that a general suppression of the hypothalamus…”

www.healthrising.org/blog/2025/12...
ME/CFS Autopsy Study Finds a Wrecked HPA Axis: The 2025 IACFS/ME Conference Report #3 - Health Rising
A Dutch ME/CFS autopsy report findings multiple severe problems in the HPA axis of ME/CFS patients.
www.healthrising.org
December 5, 2025 at 12:04 AM
Reposted
bhanlon15.bsky.social
'Microscopic Structures Found in Long COVID Blood'

'These methods allowed them to accurately differentiate Long COVID patients from healthy individuals and to pinpoint the most informative biomarker combinations.'

www.miragenews.com/microscopic-...
Microscopic Structures Found in Long COVID Blood
The researchers also incorporated Artificial Intelligence tools, including machine learning, to analyze biomarker patterns. These methods allowed them
www.miragenews.com
November 13, 2025 at 4:14 PM
Reposted
wamesmecfs.bsky.social
Lipkin's team have found evidence that the innate immune system in people with ME/CFS is hyperstimulated with different levels of metabolites & proteins. Drugs that dampen the innate immune response (e.g. interleukin-37, metformin, rapamycin) may reduce fatigue & PEM.
tinyurl.com/mr2a7uyv
Hyperstimulated Innate Immune System Can Drive ME/CFS-Associated Fatigue and Post-Exertional Malaise - Solve ME/CFS Initiative
A new study by Dr. Ian Lipkin describes how a hyperactive innate immune system can drive ME/CFS-associated fatigue and post-exertional malaise.
tinyurl.com
November 10, 2025 at 11:55 AM
Reposted
decodemestudy.bsky.social
Our initial DNA results! DecodeME have discovered that people with an ME/CFS diagnosis have significant genetic differences compared to the general population.
-
Summary of our results: shorturl.at/pgsjk
Check out our full preprint paper: shorturl.at/VwN3s
DecodeME: The Results announcement post. The graphic has a blue background with a DNA helix. In the centre of the graphic it says ‘We have released our initial DNA results! We have discovered that your genes contribute to your chances of developing ME/CFS.’ At the bottom left of the graphic is an image of a research paper.
August 6, 2025 at 6:24 PM
Reposted
jansplanet.bsky.social
Great news, possible treatment options & a better understanding of why women are disproportionately affected by ME/CFS long-COVID. 😷
#COVIDisNotOver
www.montrealgazette.com/news/health/...
July 24, 2025 at 9:52 PM
Reposted
tomkindlon.bsky.social
"An exhausted antiviral immune response is observed in myalgic encephalomyelitis/chronic fatigue syndrome (#MECFS) & long COVID. In this study, potential mechanisms behind this exhaustion were investigated"

www.mdpi.com/1999-4915/17...

Image is from AMMES June 2025 e-newsletter

#CFS
Reactivated EBV, HHV6, HAdV in Sputum from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients: Are autoAbs to IFN-I Impairing Antiviral Immunity? "An exhausted antiviral immune response is observed in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID. In this study, potential mechanisms behind this exhaustion were investigated. First, the viral load of EBV, HAdV, human cytomegalovirus (HCMV), human herpesvirus 6 (HHV6), and SARS-CoV-2 was determined in sputum samples (n=29) derived from ME/CFS patients (n=13), healthy controls (n=10), elderly healthy controls (n=4), and immunosuppressed controls (n=2). Secondly, autoAbs to type I interferon (IFN-I) in sputum were analyzed to possibly explain impaired viral immunity. We found that ME/CFS patients released EBV at a significantly higher level compared to controls (p=0.0256)."
June 7, 2025 at 10:12 PM
Reposted
tomkindlon.bsky.social
"For COVID ‘long haulers,’ glimmers of good news"

Description from Science for ME weekly update

Link:
www.bostonglobe.com/2024/10/02/m...
archive.ph/Vjq0U#select...

#LongCovid #PASC #COVID19 #COVID
Boston Globe For COVID 'long haulers', glimmers of good news On Dr. David Systrom's work at Brigham and Women's Hospital. "A growing body of research suggests that both long COVID and chronic fatigue are post-viral syndromes that result in chronic, low-grade inflammation that can damage healthy tissue and, in some cases, the production of auto-antibodies that can attack it. Systrom and others have begun to catalog the scope of the microscopic carnage caused by the immune system's friendly fire." Article (archived) l Thread
October 6, 2024 at 10:19 PM