Michele Acconcia
@mich-acconcia.bsky.social
PhD student in the @gozziale.bsky.social Functional Neuroimaging Lab
Reposted by Michele Acconcia
New Perspective from myself, Sarah Heilbronner and @myoo.bsky.social . “Rethinking the centrality of brain areas in understanding functional organization” in Nature Neuroscience. 🧵
rdcu.be/eVZ1A
rdcu.be/eVZ1A
Rethinking the centrality of brain areas in understanding functional organization
Nature Neuroscience - Parcellation of the cortex into functionally modular brain areas is foundational to neuroscience. Here, Hayden, Heilbronner and Yoo question the central status of brain areas...
rdcu.be
December 23, 2025 at 1:02 PM
New Perspective from myself, Sarah Heilbronner and @myoo.bsky.social . “Rethinking the centrality of brain areas in understanding functional organization” in Nature Neuroscience. 🧵
rdcu.be/eVZ1A
rdcu.be/eVZ1A
Reposted by Michele Acconcia
Wrapping up 2025 with the lab.
Proud moments (including some I once thought impossible) and so many failures, living side by side, as science does. We stuck with it together. Grateful for the shared effort, trust, and fun that shaped this year.
Wishing everyone a peaceful holiday break!
Proud moments (including some I once thought impossible) and so many failures, living side by side, as science does. We stuck with it together. Grateful for the shared effort, trust, and fun that shaped this year.
Wishing everyone a peaceful holiday break!
December 19, 2025 at 2:48 PM
Wrapping up 2025 with the lab.
Proud moments (including some I once thought impossible) and so many failures, living side by side, as science does. We stuck with it together. Grateful for the shared effort, trust, and fun that shaped this year.
Wishing everyone a peaceful holiday break!
Proud moments (including some I once thought impossible) and so many failures, living side by side, as science does. We stuck with it together. Grateful for the shared effort, trust, and fun that shaped this year.
Wishing everyone a peaceful holiday break!
Reposted by Michele Acconcia
How distributed is the brain-wide network that is recruited for cognition? A Perspective by Matthew C. Rosen & David J. Freedman
#neuroscience #neuroskyence
www.nature.com/articles/s41...
#neuroscience #neuroskyence
www.nature.com/articles/s41...
How distributed is the brain-wide network that is recruited for cognition? - Nature Reviews Neuroscience
Both localized and distributed views on the functional organization of the brain have been put forward. In this Perspective, Rosen and Freedman examine the degree to which these two views account for ...
www.nature.com
December 4, 2025 at 9:30 AM
How distributed is the brain-wide network that is recruited for cognition? A Perspective by Matthew C. Rosen & David J. Freedman
#neuroscience #neuroskyence
www.nature.com/articles/s41...
#neuroscience #neuroskyence
www.nature.com/articles/s41...
Reposted by Michele Acconcia
Reposted by Michele Acconcia
very nice talk by Joe McCaffrey on functional localization— it’s an easy listen with tons of great information about the debate.
m.youtube.com/watch?v=eRmD...
m.youtube.com/watch?v=eRmD...
Lunchtime Talk - Joe McCaffrey 11/7/25
YouTube video by Center for Philosophy of Science
m.youtube.com
November 9, 2025 at 9:54 PM
very nice talk by Joe McCaffrey on functional localization— it’s an easy listen with tons of great information about the debate.
m.youtube.com/watch?v=eRmD...
m.youtube.com/watch?v=eRmD...
Reposted by Michele Acconcia
🚨 New paper alert! 🚨(1/6)
Excited to share our work, out now in Science Advances
We show that a rapid norepinephrine surge along a brainstem pathway (LC→PRN) is a key driver of sound-evoked awakenings
www.science.org/doi/10.1126/...
Excited to share our work, out now in Science Advances
We show that a rapid norepinephrine surge along a brainstem pathway (LC→PRN) is a key driver of sound-evoked awakenings
www.science.org/doi/10.1126/...
An early surge of norepinephrine along brainstem pathways drives sensory-evoked awakening
The locus coeruleus has a specialized pathway to the brainstem that controls sound-evoked awakening from sleep.
www.science.org
September 10, 2025 at 6:30 PM
🚨 New paper alert! 🚨(1/6)
Excited to share our work, out now in Science Advances
We show that a rapid norepinephrine surge along a brainstem pathway (LC→PRN) is a key driver of sound-evoked awakenings
www.science.org/doi/10.1126/...
Excited to share our work, out now in Science Advances
We show that a rapid norepinephrine surge along a brainstem pathway (LC→PRN) is a key driver of sound-evoked awakenings
www.science.org/doi/10.1126/...
Reposted by Michele Acconcia
Working link to the preprint 👇
www.biorxiv.org/content/10.1...
See thread below for a looong explainer
www.biorxiv.org/content/10.1...
See thread below for a looong explainer
September 10, 2025 at 5:48 PM
Working link to the preprint 👇
www.biorxiv.org/content/10.1...
See thread below for a looong explainer
www.biorxiv.org/content/10.1...
See thread below for a looong explainer
Reposted by Michele Acconcia
Too often, I see people talk about a replication as if the first study has established something, and the replication study is a double-check. What people often fail to understand is that we do not do replication studies to *check* a finding, but to *establish* a finding. 1/x
August 17, 2025 at 6:36 AM
Too often, I see people talk about a replication as if the first study has established something, and the replication study is a double-check. What people often fail to understand is that we do not do replication studies to *check* a finding, but to *establish* a finding. 1/x
Reposted by Michele Acconcia
Thinking about writing a pop science book about the brain (“Your Brain on Everything”) where the big reveal is that all the brain names were randomized and I was actually talking about psychology the whole time.
July 13, 2025 at 8:21 PM
Thinking about writing a pop science book about the brain (“Your Brain on Everything”) where the big reveal is that all the brain names were randomized and I was actually talking about psychology the whole time.
Reposted by Michele Acconcia
Our new paper is out in Science.
We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change.
Congrats to Bin for the great thesis, and the team!
www.science.org/doi/10.1126/...
We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change.
Congrats to Bin for the great thesis, and the team!
www.science.org/doi/10.1126/...
Cholinergic feedback for modality- and context-specific modulation of sensory representations
The brain’s ability to prioritize sensory information is crucial for adaptive behavior, yet its mechanisms remain unclear. We investigated basal forebrain cholinergic neurons modulating olfactory bulb...
www.science.org
June 20, 2025 at 3:32 PM
Our new paper is out in Science.
We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change.
Congrats to Bin for the great thesis, and the team!
www.science.org/doi/10.1126/...
We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change.
Congrats to Bin for the great thesis, and the team!
www.science.org/doi/10.1126/...
Reposted by Michele Acconcia
Advances in neuroscience have yielded massive, rich datasets from various analysis techniques and modalities. 🧠📈
In a @natureneuro.bsky.social perspective, researchers underscore the importance of an integrative approach to render a more complete picture of the brain.
In a @natureneuro.bsky.social perspective, researchers underscore the importance of an integrative approach to render a more complete picture of the brain.
Integrating multimodal data to understand cortical circuit architecture and function - Nature Neuroscience
This paper discusses how experimental and computational studies integrating multimodal data, such as RNA expression, connectivity and neural activity, are advancing our understanding of the architectu...
www.nature.com
March 25, 2025 at 6:59 PM
Advances in neuroscience have yielded massive, rich datasets from various analysis techniques and modalities. 🧠📈
In a @natureneuro.bsky.social perspective, researchers underscore the importance of an integrative approach to render a more complete picture of the brain.
In a @natureneuro.bsky.social perspective, researchers underscore the importance of an integrative approach to render a more complete picture of the brain.
Reposted by Michele Acconcia
Beyond Mechanism—Extending Our Concepts of Causation in Neuroscience onlinelibrary.wiley.com/doi/10.1111/... - really pleased that this paper with Henry Potter is now published in the European Journal of Neuroscience 😊
Beyond Mechanism—Extending Our Concepts of Causation in Neuroscience
The search for neural mechanisms of behaviour often relies on a synchronic, driving view of causation, where neural activity drives more neural activity, which eventually drives behaviour. The real c...
onlinelibrary.wiley.com
March 14, 2025 at 10:25 AM
Beyond Mechanism—Extending Our Concepts of Causation in Neuroscience onlinelibrary.wiley.com/doi/10.1111/... - really pleased that this paper with Henry Potter is now published in the European Journal of Neuroscience 😊