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micoleermine.bsky.social
MicoleErmine.bsky.social
@micoleermine.bsky.social
Polymath, Artist, Chef, Animal lover
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I got to say hello to @kencougr.bsky.social and @micoleermine.bsky.social, huzzah. It's been a really long time since I've seen them in person, so I was very glad I got the chance. 😊
January 17, 2026 at 1:06 AM
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Today's low-key furry shirt.
December 11, 2025 at 7:18 PM
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that checkpoint inhibitor drugs such as anti-PD-1 therapy -already used in hospitals- work best when they expand these stem-like and metabolically fit T-cells. In contrast, people whose immune reactions were regulated by exhausted cells fared badly. When checkpoint therapy was administered with
December 9, 2025 at 5:07 PM
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“stem-like" T-cells. These cells, characterized by genes TCF1 and LEF1, could self-renew and differentiate into new waves of fighters. If these cells were removed from mouse models, immune attacks collapsed; if they were grown, tumors disappeared and survival increased. Researchers also discovered
December 9, 2025 at 5:06 PM
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chemical messenger that recruits other immune defenses. The studies showed that metabolic flexibility, not target recognition, foretells how long the immune cells will keep fighting. Among the populations of tumor-infiltrating T-cells that were so diverse, one stood out as extraordinary: a subset of
December 9, 2025 at 5:06 PM
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glycolysis, they switched to oxidative phosphorylation and fatty acid metabolism- an energy strategy that enables them to endure the long term. When researchers boosted these channels of energy in mice, the T-cells killed tumor cells better and produced higher levels of interferon-γ, an immune
December 9, 2025 at 5:05 PM
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single-cell resolution, the researchers identified a minor subset of tumor-cytotoxic cells. These cells continue to function even in oxygen-starved, nutrient-poor environments in which other immune cells do not. These hardy T-cells employed a second fuel source. Instead of combusting glucose through
December 9, 2025 at 5:05 PM
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patients, the treatments fail because immune cells become exhausted. Tumors naturally adapt to disable or tire out the same cells meant to kill them. Researchers mapped how CD8⁺ T cells-the body's own killers-are capable of surviving and fighting within solid tumors. By examining the cells at
December 9, 2025 at 5:04 PM
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place. Taken together, the breakthroughs promise a day when the body's own immune system can prevent and fight cancer with greater accuracy and endurance. Cancer immunotherapy transformed the treatment of most cancers by unleashing the potential of the immune system to kill tumors. Yet, in most
December 9, 2025 at 5:04 PM
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In a breakthrough that could potentially rewrite the prevention and treatment of cancer, researchers have discovered how certain immune cells can break through tumors’ defenses. They have also developed a new nanoscale vaccine that shows promise in preventing cancers from occurring in the first
December 9, 2025 at 5:03 PM
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Melanoma, pancreatic cancer, and triple-negative breast cancer (TNBC) are each serious clinical challenges due to how common or aggressive they are and how poorly they often respond to treatment. Which is why researchers are determined to develop an effective treatment for all of them.
December 9, 2025 at 5:03 PM
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Researchers envision their vaccine being used as both a treatment and a preventive, and as an approach to treating multiple cancer types. NOTE: This is PRECLINICAL.
www.umass.edu/news/article...

The study has been published in Cell. YES, it is PEER-REVIEWED.
www.cell.com/cell-reports...

🧪🧵⬇️
December 9, 2025 at 5:02 PM
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GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.
December 9, 2025 at 5:00 PM
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Hit the trail! 🪧

[ #art #designs ]
December 2, 2025 at 9:41 PM
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Snow day! I think this was my most widely-shared piece on the dead bird site. ❄

#art #animals
December 29, 2024 at 5:00 PM
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Butlerian Jihad incoming.
Pope Leo XIV told students not to use artificial intelligence for homework, saying that AI ‘won’t stand in authentic wonder before the beauty of God’s creation.’
Even God Is Worried About ChatGPT
Pope Leo XIV told students not to use artificial intelligence for homework, saying that AI ‘won’t stand in authentic wonder before the beauty of God’s creation.’
www.vulture.com
November 26, 2025 at 9:57 PM
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It's a tradition in Scotland for the road gritters too
November 24, 2025 at 9:15 PM
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They named the snowplows 🥹
November 24, 2025 at 8:51 PM
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Time for another #OldArtMonday

Here is "Topher, the world's cutest otter" -- but giant.

The pencils are from 1988 by @kencougr.bsky.social

The inked image is from 1989 by Topher's creator Deal Whitley.

Ken would have fun drawing people's characters giant with the byline "slightly altered."
November 24, 2025 at 7:08 PM
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It looks like Terrie Smith will need heart surgery for a leaky valve. She could use your support more than ever.

www.furaffinity.net/journal/1125...

She's currently posting colorized Havoc Inc. pages on her Patreon, consider subscribing or sending a donation.

www.patreon.com/TerrieSmith
Get more from Terrie Smith on Patreon
Patreon is empowering a new generation of creators. Support and engage with artists and creators as they live out their passions!
www.patreon.com
November 24, 2025 at 11:04 PM
Patrick Fitzgerald came out of retirement to represent James Comey for free against the actual-whole DOJ and in one month of opening exchanges, he's about to get the Attorney General fired.

He came to get down.
In defending the appointment of Lindsey Halligan, Trump's DOJ says it disagrees with aspects of Judge Aileen Cannon's ruling that disqualified Jack Smith. www.politico.com/news/2025/11...
November 24, 2025 at 10:52 PM
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This dimwitted coward is taking on *Mark Kelly*? Space station commander combat tested Navy aviator Mark Kelly?

🍿🍿🍿🍿🍿🍿🍿
Of course Kegsbreath had to chime in & try to outdo his boss w his own performative outrage, giving what is "an extreme response to a video that was very tame, measured, and rooted in the military’s own words."

What's that they say about 'he who doth protest too much' ???
Hegseth Helps Trump Take Revenge on Democrats for Message to Troops
The revenge crusade is beginning with Mark Kelly.
newrepublic.com
November 24, 2025 at 10:30 PM
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November 5, 2025 at 1:08 PM
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November 7, 2025 at 12:40 PM
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November 24, 2025 at 1:16 PM