Milo B. Fasken, Ph.D.
@milofasken.bsky.social
4K followers
14K following
290 posts
Senior Scientist, Department of Biology, Emory University, Atlanta, GA.
Molecular Biologist. RNA Scientist. Yeast Geneticist 🧬. British🇬🇧. Runner 🏃🏻…. Opinions are my own.
Interests: RNA Decay, RNA Processing, RNA & Disease.
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Reposted by Milo B. Fasken, Ph.D.
Reposted by Milo B. Fasken, Ph.D.
Eugene Valkov
@eugenevalkov.bsky.social
· Jul 13
Intracellular pathogen effector reprograms host gene expression by inhibiting mRNA decay - Nature Communications
Intracellular pathogens hijack host gene expression to subvert cellular processes. Here, the authors show that Legionella pneumophila’s PieF effector inhibits the human CCR4-NOT deadenylation machiner...
www.nature.com
Reposted by Milo B. Fasken, Ph.D.
Nikos Kouvelas
@nickkouvelas.bsky.social
· Jul 13
m6A alters ribosome dynamics to initiate mRNA degradation
m6A is a potent inducer of ribosome stalling and collisions that trigger YTHDF-mediated
mRNA degradation, a process that highlights the ribosome as a critical sensor linking
translation dynamics to m6...
www.cell.com
