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Montse Cols @montse-jexpmed.bsky.social · 13d

Check this out before the deadline and see you in Seattle!

Montse Cols @montse-jexpmed.bsky.social · 13d

For September’s #JEMjc we would like to highlight the recent description of septal macrophages controlling adipocyte tissue plasticity www.science.org/doi/10.1126/...

Septal LYVE1+ macrophages control adipocyte stem cell adipogenic potential

Tissue macrophages reside in anatomically distinct subtissular niches that shape their identity and function. In white adipose tissue (WAT), we identified three macrophage populations with distinct lo...

www.science.org

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Montse Cols @montse-jexpmed.bsky.social · 21d

Back to school, back-to-back #JEMLegacy with this study of neutralization tests for poliomyelitis in newborn infants and mothers…from 1930! tinyurl.com/59nnnuan

IMMUNITY TO POLIOMYELITIS IN MOTHERS AND THE NEWBORN AS SHOWN BY THE NEUTRALIZATION TEST

Neutralization tests for the virus of poliomyelitis on blood serum of urban mothers and their newborn infants showed that immunity was present in ten out o

tinyurl.com

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Montse Cols @montse-jexpmed.bsky.social · 21d

Back to school time of year with this #JEM_Spotlight describing the γδ T cell profiling of pre-term infants as a first line of defense for neonates tinyurl.com/3hz73p2v

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Reposted by Montse Cols

Journal of Experimental Medicine @jem.org · May 6

JEM's Deputy Editor Gaia Trincucci (@gaiajexpmed.bsky.social) and @rupress.org's Ben Short at #AAI2025! Today's our final day -- come by our booth #811 and say hi! Don't forget to pick up our latest Immunology collection 📚 + souvenir 🏝️

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Reposted by Montse Cols

Rod Rahimi @rodrahimi.bsky.social · Nov 29

Friends, it's fun to see the #immunology community continue to grow! I created a 4th Starter Pack to help folks find each other. If you're an immunologist and you don't see yourself on the lists, let me know 🧪

go.bsky.app/PY5tCas

go.bsky.app/FmERUoD

go.bsky.app/6aT6qDS

go.bsky.app/QSEPDoj

Rod Rahimi @rodrahimi.bsky.social · Nov 19

Friends, the second #immunology starter pack filled in 3 days! I started a third to help folks new to BlueSky rebuild their network

Below are the links

If you're an immunologist and I have missed you so far, let me know 🧪

go.bsky.app/PY5tCas

go.bsky.app/FmERUoD

go.bsky.app/6aT6qDS

Rod Rahimi @rodrahimi.bsky.social · Nov 15

Wonderful to see the #immunology community growing here.

The first starter pack is full (they cap at 150), so I created a second one. Let me know if you'd like to be added

go.bsky.app/PY5tCas

go.bsky.app/FmERUoD

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Reposted by Montse Cols

Journal of Experimental Medicine @jem.org · Mar 3

In new study, Simchoni et al. from Anthony Shum's lab (rupress.org/jem/article/...) compared five families and multiple generations to find a gene variant that prevents COPA Syndrome and opens the door to a new gene therapy for the condition. More from UCSF News: www.ucsf.edu/news/2025/02...

1 Gene Variant Is Poised to Cure a Devastating Inherited Disease

COPA syndrome causes lung hemorrhaging starting in childhood. But one in three people with the disease mutation are spared. UCSF scientists have discovered how a separate gene variant protects those r...

www.ucsf.edu

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Montse Cols @montse-jexpmed.bsky.social · Feb 28

#RareDiseaseDay2025 @jem.org where we remain committed to publishing studies that identify inborn errors of immunity, elucidate underlying mechanisms and propose potential treatments for rare diseases. Some recent examples: doi.org/10.1084/jem.20240827 doi.org/10.1084/jem.20240843

HMCN1 variants aggravate epidermolysis bullosa simplex phenotype | Journal of Experimental Medicine | Rockefeller University Press

Mutations in the KRT14 gene cause epidermolysis bullosa simplex (EBS), featuring abnormal basement membrane zone (BMZ) function. We identified deleterious

doi.org

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Reposted by Montse Cols

Journal of Experimental Medicine @jem.org · Feb 27

KLF2 expression in IgG plasma cells at their induction site regulates the migration program, say Wataru Ise, Takuya Koike, Tomohiro Kurosaki @osaka_univ_e and colleagues: buff.ly/41bbKEF

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Reposted by Montse Cols

Eric Topol @erictopol.bsky.social · Feb 27

Tomorrow is #RareDiseaseDay. An exciting discovery today for COPA syndrome, a rare heritable autoimmune disease. Finding a protective allele that has the potential to lead to a cure
rupress.org/jem/article/...

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Reposted by Montse Cols

Journal of Experimental Medicine @jem.org · Feb 21

Tejedor Vaquero, Neuman et al. @gmagrilab.bsky.social demonstrate immunomolecular and reactivity landscapes of gut IgA subclasses in homeostasis and inflammatory bowel disease. https://buff.ly/4jVJYV5

📘 In Host–Microbe Interactions 2025 👉 https://buff.ly/40XMv8r

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Reposted by Montse Cols

Journal of Experimental Medicine @jem.org · Feb 19

Kellog, @reboldilab.bsky.social, Vanni et al. reveal that #microbiome-driven tuft cells’ hyperplasia in the colon helps defend against Clostridioides difficile infection. https://buff.ly/3CRIPNy

📘 In Host–Microbe Interactions 2025 👉 https://buff.ly/40XMv8r

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Reposted by Montse Cols

Richard Sever @richardsever.bsky.social · Feb 14

Mike Lauer follows Lawrence Tabak out the door at NIH www.statnews.com/2025/02/13/n...

Second top NIH official, who oversaw awarding of research grants, departs abruptly

Michael Lauer, deputy director of the National Institutes of Health’s extramural research, will leave the agency at the end of the week.

www.statnews.com

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Reposted by Montse Cols

Journal of Experimental Medicine @jem.org · Feb 7

Suin Jo, Kenneth Murphy et al. @washumedicine.bsky.social utilize several genetic models to distinguish roles of cDC1 and cDC2 in presentation of different forms of antigens to CD4⁺ and CD8⁺ T cells in vivo. https://buff.ly/42LUFDr

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Reposted by Montse Cols

Casanova Lab @casanovalab.bsky.social · Feb 6

1/ Spots are still open for the 2025 Henry Kunkel Society Meeting on Genes & Immunity!
Join us in Belgrade from April 10-12, 2025.
www.henrykunkelsociety.org/meetings/
#HKS2025 #Immunology 🧬🔬

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Reposted by Montse Cols

Elisabeth Bik - Perpetrator 5, a fraudulent microbiologist @elisabethbik.bsky.social · Feb 8

NIH plans to slash support for indirect research costs, sending shockwaves through science
Capping these payments would ‘just grind our scientific complex to a halt,’ one researcher said
@statnews.com

www.statnews.com/2025/02/07/n...

NIH plans to slash support for indirect research costs, sending shockwaves through science

The NIH said Friday night that it would slash support for indirect costs on all existing and future grants to 15%

www.statnews.com

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Reposted by Montse Cols

Journal of Experimental Medicine @jem.org · Feb 5

Insights from Cadena & Blumenthal: Bernaleau et al. @rebsamenlab.bsky.social (https://buff.ly/3ZrE70d) show that CCDC134 located in the ER is required for TLR biogenesis by controlling the N-glycosylation, folding, and stabilization of the ER chaperone Gp96. https://buff.ly/4gwjt5N

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Montse Cols @montse-jexpmed.bsky.social · Feb 2

Looking forward to this one. Come and say hi! 👋

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Reposted by Montse Cols

Nature @nature.com · Jan 29

“It will be much easier to destroy the world’s greatest scientific ecosystem than it will be to try to rebuild it”

Scientists are worried about the long-term effects of the Trump administration’s actions

https://go.nature.com/3PUKeGc

Chaos erupts in US science as Trump’s team declares freeze on federal grants

The freeze’s effect on research is still unclear, but scientists fear ‘incalculable’ damage.

go.nature.com

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Reposted by Montse Cols

Rockefeller University Press @rupress.org · Jan 16

We’re thrilled to announce our partnership with the International Alliance for Primary Immunodeficiency Societies (#IAPIDS) to launch the Journal of Human Immunity (JHI) @jhumimmunity.org (https://buff.ly/3PAEMrK)! Groundbreaking, #OpenAccess research on #HumanImmunity 👉 https://buff.ly/4ajqm8W

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Montse Cols @montse-jexpmed.bsky.social · Jan 17

Exciting news at RUP! Many congratulations @casanova and colleagues

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Journal of Experimental Medicine @jem.org · Jan 6

Our January Issue is here ✨ https://buff.ly/3W45Raw
The image shows CD206+ #macrophage population marked by Venus expression (yellow) in B78chOVA tumor slices with transferred OT-I T cells marked by CD2dsRed (red). From Arja Ray, @maxkrummel.bsky.social et al. (https://buff.ly/3DHWwPl)

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Journal of Experimental Medicine @jem.org · Dec 11

Our annual "Best of JEM" series highlights some of the most exciting studies from the last 12 months. We present you with research in basic #immunology, #immunotherapy and tumor immunology, inborn errors of immunity, #neurodegeneration, & #inflammation: https://buff.ly/4iwWcCJ

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Reposted by Montse Cols

Science Magazine @science.org · Dec 17

Breaking news: A 2020 paper that sparked widespread enthusiasm for hydroxychloroquine as a #COVID19 treatment has been retracted, following campaigning by scientists who alleged the research contained major scientific flaws and may have breached ethics regulations. scim.ag/4iR9bQ6

Infamous paper that popularized unproven COVID-19 treatment finally retracted

Study on hydroxychloroquine by Didier Raoult and colleagues gets pulled on ethical and scientific grounds

scim.ag

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